ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer.
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About
Research Fellow at Newcastle University Centre for Cancer. Interests: stem cell models, prostate cancer biology, organogenesis and genome editing. š¬
Work
Newcastle University
|Prostate Cancer UK Fellow
United Kingdom of Great Britain and Northern Ireland
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Publications
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer
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Communications Biology
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Engineering prostate cancer in vitro: what does it take?
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Oncogene
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Human prostate organoid generation and the identification of prostate development drivers using inductive rodent tissues
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Development
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ST6GAL1āmediated aberrant sialylation promotes prostate cancer progression
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The Journal of Pathology
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Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patientāinduced pluripotent stem cellāderived retinal pigment epithelium cells
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Clinical and Translational Medicine
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A Review of Prostate Organogenesis and a Role for iPSC-Derived Prostate Organoids to Study Prostate Development and Disease
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International Journal of Molecular Sciences
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Modified CRISPR/Cas9 mediated generation of two MKK7 knockout human embryonic stem cell lines.
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Stem cell research
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A Review of Prostate Organogenesis and a Role for iPSC-Derived Prostate Organoids to Study Prostate Development and Disease
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International Journal of Molecular Sciences
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Engineering Prostate Cancer from Induced Pluripotent Stem CellsāNew Opportunities to Develop Preclinical Tools in Prostate and Prostate Cancer Studies
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International Journal of Molecular Sciences
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Propagation of human prostate tissue from induced pluripotent stem cells
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Stem Cells Translational Medicine
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AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/ā iPSC-Derived RPE Cells
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Molecular Therapy - Methods & Clinical Development
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Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
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Nature Communications
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Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243Aā>āG mitochondrial DNA mutation
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Scientific Reports
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An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure
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STEM CELLS
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CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cells
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Cell Death & Disease
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An X-chromosome pentaplex in two linkage groups: Haplotype data in Alagoas and Rio de Janeiro populations from Brazil
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Forensic Science International: Genetics
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Mitochondrial DNA Control Region Polymorphism in the Population of Alagoas State, North-Eastern Brazil
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Journal of Forensic Sciences
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