Ameen Ali Abu-Hashem Mostafa El-Fakey

Professor of Organic Chemistry
National Research Centre, Giza, Egypt., 12622, Dokki, Giza, Egypt., Giza, EG.

About

Highly distinguished Professor of Organic Chemistry with over 30 years of experience in advanced research, synthetic methodologies, and drug development. Recognized as a top 2% global scientist by Stanford University and awarded 'Best Researcher' for two consecutive years (2022-2023) by the Global Science Father Foundation. Authored over 90 scientific papers (h-index 33, 3200+ citations) and supervised numerous theses, driving innovation in medicinal and heterocyclic chemistry.

Work

National Research Centre (NRC)
|

Professor of Organic Chemistry

Giza, Giza, Egypt

Summary

Leads advanced research in organic and medicinal chemistry, focusing on synthetic methodologies and biological activities of heterocyclic compounds, while mentoring scientific theses and contributing to global scientific advancements.

Highlights

Spearheaded extensive scientific research, resulting in over 90 published papers in international scientific journals and numerous supervised scientific theses.

Recognized as a top 2% distinguished scientist globally by Stanford University for five consecutive years (2021-2025).

Awarded 'Best Researcher' for two consecutive years (2022-2023) in organic and medicinal chemistry by the Global Science Father Foundation.

Contributed to the development of synthetic methodologies for biologically active heterocyclic compounds, advancing pharmaceutical research.

Maintained a high scientific impact with an h-index of 33, i10-index of 63, and over 3212 citations as of January 2026.

Jazan University
|

Associate Professor of Organic Chemistry

Jazan, Jazan, Saudi Arabia

Summary

Teaches organic chemistry courses and conducts significant research within the Chemistry Department, contributing to academic excellence and scientific innovation.

Highlights

Delivered comprehensive organic chemistry courses to college students, enhancing their understanding of complex chemical principles.

Participated actively in scientific projects and social societies, fostering collaborative research and community engagement.

Presented research at numerous international scientific conferences, contributing to the global scientific discourse.

Awarded 'Excellence in Research' and 'Honourable Achievement in Innovative Research' by the International Research Awards on Science, Health and Engineering in 2023.

Served as an Editorial Board Member for the 14th International Conference on Science, Health and Engineering in 2023, demonstrating leadership in academic publishing.

National Research Centre (NRC)
|

Assistant Professor of Organic Chemistry

Giza, Giza, Egypt

Summary

Conducted advanced research in photochemistry and organic chemistry, contributing to novel compound synthesis and chemical industrial applications.

Highlights

Led research initiatives focused on the synthesis of new organic compounds with potential biological activities.

Mentored junior researchers and contributed to the scientific output of the Photochemistry Department.

Collaborated on projects to develop chemical industrial applications based on organic chemistry principles.

National Research Centre (NRC)
|

Researcher, Department of Photochemistry, Organic Chemistry, Chemical Industrial Institute

Giza, Giza, Egypt

Summary

Engaged in specialized research within the Department of Photochemistry and Organic Chemistry, focusing on chemical industrial applications.

Highlights

Executed complex organic synthesis experiments, contributing to the development of new chemical entities.

Analyzed research data and prepared reports on findings for internal and external dissemination.

Supported departmental objectives through dedicated research efforts and technical contributions.

National Research Centre (NRC)
|

Assistant Researcher, Department of Photochemistry, Organic Chemistry, Chemical Industrial Institute

Giza, Giza, Egypt

Summary

Assisted senior researchers in photochemistry and organic chemistry projects, developing foundational research skills and contributing to experimental design and execution.

Highlights

Supported the design and implementation of experiments for synthesizing organic compounds.

Contributed to data collection and preliminary analysis for various research projects.

Developed proficiency in laboratory techniques and research methodologies under expert guidance.

Environmental System of Egypt
|

Researcher of Environmental Issues

Egypt

Summary

Conducted research on environmental issues, specifically focusing on preserving natural reserves from pollution and developing sustainable solutions.

Highlights

Investigated methods for pollution prevention and environmental protection within natural reserves.

Developed research proposals and reports on ecological impact assessments.

Contributed to strategies aimed at maintaining biodiversity and ecosystem integrity.

Sekam Company
|

Researcher, Department of Quality Control and Pharmacology

Cairo, Cairo, Egypt

Summary

Performed research in quality control and pharmacology, ensuring the efficacy and safety of pharmaceutical products.

Highlights

Conducted quality control analyses on pharmaceutical drugs, ensuring compliance with industry standards.

Participated in pharmacological studies to evaluate drug properties and effects.

Contributed to product development by applying expertise in drug synthesis and coating technologies.

Education

Cairo University
Cairo, Cairo, Egypt

PhD

Organic Chemistry

Courses

Applied Chemistry

Heterocyclic Chemistry

Aromatic and Aliphatic Chemistry and Reaction Mechanism

Spectroscopy (IR, ¹H-NMR, ¹³C-NMR)

General Chemistry

Natural products

Biochemistry (Carbohydrates, Lipids and Proteins)

Medicinal chemistry

Stereochemistry

Physical Organic Chemistry

El-Mansoura University
Egypt

M.Sc.

Organic Chemistry

Zagazig University
Zagazig, Zagazig, Egypt

B.Sc.

Chemistry

Awards

Editorial Board Member

Awarded By

International Conference on Science, Health and Engineering

Appointed as an Editorial Board Member for contribution and honorable achievement in innovative research during the 14th Edition of International Conference on Science, Health and Engineering.

Excellence in Research Award

Awarded By

International Research Awards on Science, Health and Engineering

Awarded for excellence in research and honorable achievement during the 13th Edition of International Research Awards on Science, Health and Engineering.

Best Researcher Award for Innovative Research

Awarded By

International Research Awards on Science, Health and Engineering

Awarded for significant contributions and honorable achievement in innovative research during the 13th Edition of International Research Awards on Science, Health and Engineering.

Best Researcher Award

Awarded By

Global Science Father Foundation

Recognized as 'Best Researcher' at the world level in organic and medicinal chemistry and its applications for two consecutive years (2022-2023).

Distinguished Scientist (Top 2%)

Awarded By

Stanford University

Selected among the best-distinguished scientists globally within a top 2% list, according to the classification of Stanford University, for five consecutive years (2021-2025).

Publications

Synthesis and Antimicrobial Evaluation of Novel Triazole, Tetrazole, and Spiropyrimidine-Thiadiazole Derivatives.

Published by

Polycyclic Aromatic Compounds

Summary

Explored the synthesis and antimicrobial activity of novel triazole, tetrazole, and spiropyrimidine-thiadiazole derivatives, contributing to the development of new antimicrobial agents.

Synthesis and Antimicrobial Activity of Novel 1, 2, 4-Triazolopyrimidofuro-quinazolinones from Natural Furochromones (Visnagenone and Khellinone).

Published by

Medicinal Chemistry

Summary

Investigated the synthesis and antimicrobial activity of novel triazolopyrimidofuro-quinazolinones derived from natural furochromones, including visnaginone and khellinone.

Synthesis of Novel Benzodifuranyl, 1, 3, 5-Triazines, 1, 3, 5-Oxadiazepines, and Thiazolopyrimidines Derived from Visnaginone and Khellinone as Anti-Inflammatory and Analgesic Agents.

Published by

Molecules

Summary

Synthesized and evaluated novel benzodifuranyl, triazines, oxadiazepines, and thiazolopyrimidines derived from visnaginone and khellinone for their anti-inflammatory and analgesic properties.

Design, Synthesis, and Anticancer Potential of the Enzyme (PARP-1) Inhibitor with Computational Studies of New Triazole, Thiazolidinone, -Thieno [2, 3-d] Pyrimidinones.

Published by

Letters in Drug Design & Discovery

Summary

Designed, synthesized, and computationally studied new triazole, thiazolidinone, and thieno pyrimidinones as potential PARP-1 enzyme inhibitors for anticancer applications.

Recent Development in the Chemistry of Bicyclic 6+5 Systems, Part II: Chemistry of Triazolopyrimidine Derivatives.

Published by

Letters in Organic Chemistry

Summary

Reviewed recent advancements in the chemistry of bicyclic 6+5 systems, focusing specifically on triazolopyrimidine derivatives.

Languages

Arabic
English

Certificates

Applications of Nanotechnology in Industry Workshop

Issued By

The Islamic Development Bank - National Research Centre

LOCAL TOEFL.ITP-English

Issued By

Cairo University

I.C.D.L. (Computer) Skills

Issued By

Cairo University

Proton Magnetic Resonance (H¹-NMR, Systems)

Issued By

National Research Centre, Egypt

Spectroscopic Analysis & SPSS Program

Issued By

National Research Centre, Egypt

Natural Product Extraction

Issued By

Sekam Pharmaceutical Company

Pharmaceutical Drug Synthesis & Tablet Coating

Issued By

Memphis Pharmaceutical Company

Skills

Organic Chemistry

Heterocyclic Chemistry, Aromatic and Aliphatic Chemistry, Reaction Mechanisms, Stereochemistry, Physical Organic Chemistry, Pyrimidine Derivatives, Quinoline Derivatives, Thiazole Derivatives, Drug Building Blocks, Organocatalysts, Green Chemistry, Synthetic Methodologies.

Analytical Techniques

Spectroscopy (IR, ¹H-NMR, ¹³C-NMR, Mass, GC-Mass), Proton Magnetic Resonance (H¹-NMR, Systems).

Pharmaceutical Research

Drug Synthesis, Medicinal Chemistry, Natural Product Extraction, Tablet Coating, Anti-inflammatory Agents, Analgesic Agents, Antimicrobial Agents, Antiviral Agents, Antioxidant Agents, Anticancer Agents, Pharmacological Activities.

Research & Development

Scientific Research, Project Management, Thesis Supervision, Experimental Design, Data Analysis (SPSS), Scientific Writing, Peer Review, Molecular Docking, ADMET Analysis.

Environmental Science

Environmental Issues, Pollution Preservation, Natural Reserves, Antifouling Polymers, Wastewater Treatment.

Computing & Languages

I.C.D.L. (Computer Skills), English (TOEFL.ITP), Arabic.

Projects

Synthesis and Design of Drug Building Blocks and New Organocatalysts from Active Chiral Amine Derivatives

Summary

Explored the synthesis and design of drug building blocks and organocatalysts from active chiral amine derivatives.

The better development of drugs and food supplements found in natural products by using green and synthetic chemistry

Summary

Focused on enhancing drug and food supplement development from natural products via green and synthetic chemistry approaches.

Synthesis: Design new quinoline derivative drugs by investigating their antimicrobial, antiviral, antioxidant, and anti-cancer properties and their ability to protect DNA

Summary

Designed novel quinoline derivatives, evaluating their antimicrobial, antiviral, antioxidant, and anti-cancer properties and DNA protection capabilities.

Developing and Synthesizing Eco-Friendly New Drugs from Natural Products and Heterocyclic Organic Compounds While Studying Their Biological and Ecological Activities as Antiviral, Antiproliferative, Antimicrobial, and Anti-fouling Agents

Summary

Engaged in the development and synthesis of eco-friendly new drugs from natural products and heterocyclic organic compounds, studying their biological and ecological activities.

Removal of hazardous organic pollutants from wastewater by bentonite clay grafted with AMPS by radiation-induced graft polymerisation

Summary

Researched the removal of hazardous organic pollutants from wastewater using modified bentonite clay.

Synthesis of antifouling polymers and testing their biological and ecological activities

Summary

Developed and tested antifouling polymers for biological and ecological applications.

Synthesis, reactions of 1, 3, 7-trimethyl-3,7-dihydro-purine-2,6-dione and study the side effects of caffeine on humans

Summary

Investigated synthesis and reactions of purine derivatives and their effects, specifically caffeine, on humans.

Efficient Chiral Amine Synthesis - Pharmaceutical Building Blocks and New Organocatalysts

Summary

Focused on efficient synthesis of chiral amines for pharmaceutical building blocks and novel organocatalysts.

Novel Synthesis of pyrimidine derivatives and nucleoside analogues

Summary

Developed new pyrimidine derivatives and nucleoside analogues with expected biological activities (anti-inflammatory, analgesic, antiviral, antioxidant).