The pro-inflammatory cytokines IFN-α and TNF-α inhibit organoid-derived extravillous trophoblast invasion
Summary
preprint
Ans van Pelt
Work
University of Amsterdam
|Full faculty member Amsterdam UMC in University Research advisory committee UvA
Netherlands
→
University of Amsterdam
|Alternate faculty member Amsterdam UMC in University Research advisory committee UvA
Netherlands
→
AMC Centrum voor Voortplantingsgeneeskunde
|Head Reproductive Biology Laboratory
Netherlands
→
University of Amsterdam
|Full Professor
Netherlands
→
AMC Centrum voor Voortplantingsgeneeskunde
|Associate Professor
Netherlands
→
AMC Centrum voor Voortplantingsgeneeskunde
|Assistant Professor
Netherlands
→
Universiteit Utrecht
|Assistant Professor
Netherlands
→
Universiteit Utrecht
|Post Doc
Netherlands
→
Education
Universiteit Utrecht
Netherlands
→
PhD
Publications
Stem cell-derived gametes: what to expect when expecting their clinical introduction
Published by
Human Reproduction
Summary
journal-article
Building a human pluripotent stem cell-based gonadal niche: improving in vitro systems with in vivo insights
Published by
Human Reproduction Update
Summary
journal-article
Impacts of cancer therapy on male fertility: Past and present
Published by
Molecular Aspects of Medicine
Summary
journal-article
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells
Published by
Cell Death & Disease
Summary
journal-article
EP300 facilitates human trophoblast stem cell differentiation
Published by
Proceedings of the National Academy of Sciences
Summary
journal-article
How germline genes promote malignancy in cancer cells
Published by
BioEssays
Summary
journal-article
Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis: a retrospective study of a male fertility preservation cohort
Summary
other
The risk of hypogonadism after testicular sperm extraction in men with various types of azoospermia: a prospective cohort study
Published by
Reproductive BioMedicine Online
Summary
journal-article
Fathering a child after childhood cancer treatments
Published by
Tijdschrift voor Urologie
Summary
journal-article
Transcriptional comparison of testicular adrenal rest tumors with fetal and adult tissues
Published by
European Journal of Endocrinology
Summary
journal-article
Spermatogonial Stem Cell-Based Therapies: Taking Preclinical Research to the Next Level
Published by
Frontiers in Endocrinology
Summary
journal-article
Impact of restoring male fertility with transplantation of in vitro propagated spermatogonial stem cells on the health of their offspring throughout life
Published by
Clinical and Translational Medicine
Summary
journal-article
Fertility preservation for male patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group
Published by
The Lancet Oncology
Summary
journal-article
Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group
Published by
The Lancet Oncology
Summary
journal-article
Bi-allelic variants in DNA mismatch repair proteins MutS Homolog <i>MSH4</i> and <i>MSH5</i> cause infertility in both sexes
Published by
Human Reproduction
Summary
journal-article
Histological study on the influence of puberty suppression and hormonal treatment on developing germ cells in transgender women
Published by
Human Reproduction
Summary
journal-article
Meiotic Chromosome Synapsis and XY-Body Formation In Vitro
Published by
Frontiers in Endocrinology
Summary
journal-article
Tumors widely express hundreds of embryonic germline genes
Summary
preprint
In Vitro Meiosis of Male Germline Stem Cells
Published by
Stem Cell Reports
Summary
journal-article
Tumors Widely Express Hundreds of Embryonic Germline Genes
Published by
Cancers
Summary
journal-article
ITGA6+ Human Testicular Cell Populations Acquire a Mesenchymal Rather than Germ Cell Transcriptional Signature during Long-Term Culture
Published by
International Journal of Molecular Sciences
Summary
journal-article
A comparative analysis of human adult testicular cells expressing stem Leydig cell markers in the interstitium, vasculature, and peritubular layer
Published by
Andrology
Summary
journal-article
The initial maturation status of marmoset testicular tissues has an impact on germ cell maintenance and somatic cell response in tissue fragment culture
Published by
Molecular Human Reproduction
Summary
journal-article
Infertility-Causing Haploinsufficiency Reveals TRIM28/KAP1 Requirement in Spermatogonia
Published by
Stem Cell Reports
Summary
journal-article
Comparison of DNA methylation patterns of parentally imprinted genes in placenta derived from IVF conceptions in two different culture media
Published by
Human Reproduction
Summary
journal-article
Comparing genome-scale DNA methylation and CNV marks between adult human cultured ITGA6+ testicular cells and seminomas to assess in vitro genomic stability
Published by
PLOS ONE
Summary
journal-article
Fertility preservation in boys: recent developments and new insights †
Published by
Human Reproduction Open
Summary
journal-article
Human Testis Phosphoproteome Reveals Kinases as Potential Targets in Spermatogenesis and Testicular Cancer
Published by
Molecular & Cellular Proteomics
Summary
journal-article
Simultaneous Purification of Round and Elongated Spermatids from Testis Tissue Using a FACS‐Based DNA Ploidy Assay
Published by
Cytometry Part A
Summary
journal-article
TorsinA Is Functionally Associated with Spermatogenesis
Published by
Microscopy and Microanalysis
Summary
journal-article
Assessment of fresh and cryopreserved testicular tissues from (pre)pubertal boys during organ culture as a strategy for in vitro spermatogenesis
Published by
Human Reproduction
Summary
journal-article
Primary human testicular PDGFRα+ cells are multipotent and can be differentiated into cells with Leydig cell characteristics in vitro
Published by
Human Reproduction
Summary
journal-article
Strains matter: Success of murine in vitro spermatogenesis is dependent on genetic background
Published by
Developmental Biology
Summary
journal-article
Characterization and population dynamics of germ cells in adult macaque testicular cultures
Published by
PLOS ONE
Summary
journal-article
Preantral follicular atresia occurs mainly through autophagy, while antral follicles degenerate mostly through apoptosis
Published by
Biology of Reproduction
Summary
journal-article
A practical blueprint to systematically study life-long health consequences of novel medically assisted reproductive treatments.
Published by
Human reproduction (Oxford, England)
Summary
journal-article
What is the best protocol to cryopreserve immature mouse testicular cell suspensions?
Published by
Reproductive BioMedicine Online
Summary
journal-article
Distinct prophase arrest mechanisms in human male meiosis.
Published by
Development (Cambridge, England)
Summary
journal-article
Characterization of Human Mesenchymal Stem Cells Isolated from the Testis
Published by
Stem Cells International
Summary
journal-article
The risk of TESE-induced hypogonadism: a systematic review and meta-analysis
Published by
Human Reproduction Update
Summary
journal-article
Long-term health in recipients of transplanted in vitro propagated spermatogonial stem cells.
Published by
Human reproduction (Oxford, England)
Summary
journal-article
What is the best protocol to cryopreserve immature mouse testicular cell suspensions?
Published by
Reproductive biomedicine online
Summary
journal-article
Descriptive analysis of lap1 distribution and that of associated proteins throughout spermatogenesis
Published by
Membranes
Summary
journal-article
Development of the testis in pre-pubertal boys with cancer after biopsy for fertility preservation
Published by
Human Reproduction
Summary
journal-article
Distinct prophase arrest mechanisms in human male meiosis
Summary
other
Fertility preservation in pre-pubertal and young males
Published by
Endocrine Abstracts
Summary
journal-article
Decreased spermatogonial quantity in prepubertal boys with leukaemia treated with alkylating agents
Published by
Leukemia
Summary
journal-article
Unraveling transcriptome dynamics in human spermatogenesis
Published by
Development
Summary
journal-article
Doxorubicin and vincristine affect undifferentiated rat spermatogonia
Published by
Reproduction
Summary
journal-article
Emi2 Is Essential for Mouse Spermatogenesis
Published by
Cell Reports
Summary
journal-article
Establishing reference values for age-related spermatogonial quantity in prepubertal human testes: a systematic review and meta-analysis
Published by
Fertility and Sterility
Summary
journal-article
Spermatogonial stem cell autotransplantation and germline genomic editing: A future cure for spermatogenic failure and prevention of transmission of genomic diseases
Published by
Human Reproduction Update
Summary
journal-article
Prenatal undernutrition and leukocyte telomere length in late adulthood: The Dutch famine birth cohort study<sup>1</sup>
Published by
American Journal of Clinical Nutrition
Summary
journal-article
A European perspective on testicular tissue cryopreservation for fertility preservation in prepubertal and adolescent boys
Published by
Human Reproduction
Summary
journal-article
AZFc deletions do not affect the function of human spermatogonia in vitro
Published by
Molecular Human Reproduction
Summary
journal-article
Artificial gametes: A systematic review of biological progress towards clinical application
Published by
Human Reproduction Update
Summary
journal-article
Cryopreservation of testicular tissue before long-term testicular cell culture does not alter in vitro cell dynamics
Published by
Fertility and Sterility
Summary
journal-article
Spatial and temporal expression of immunoglobulin superfamily member 1 in the rat
Published by
Journal of Endocrinology
Summary
journal-article
Stem cells in reproductive medicine: Ready for the patient?
Published by
Human Reproduction
Summary
journal-article
Genetic and epigenetic stability of human spermatogonial stem cells during long-term culture
Published by
Fertility and Sterility
Summary
journal-article
Enrichment of spermatogonial stem cells from long-term cultured human testicular cells
Summary
journal-article
Eliminating acute lymphoblastic leukemia cells from human testicular cell cultures: A pilot study
Summary
journal-article
Transgenic overexpression of regucalcin leads to suppression of thapsigargin- and actinomycin D-induced apoptosis in the testis by modulation of apoptotic pathways
Summary
journal-article
Mesenchymal origin of multipotent human testis-derived stem cells in human testicular cell cultures
Summary
journal-article
Restoring fertility in sterile childhood cancer survivors by autotransplanting spermatogonial stem cells: Are we there yet?
Summary
journal-article
Assuring safety without animal testing: The case for the human testis in vitro
Summary
journal-article
Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis
Summary
journal-article
Studying nonobstructive azoospermia in cystinosis: Histologic examination of testes and epididymis and sperm analysis in a Ctns -/- mouse model
Summary
journal-article
Molecular control of rodent spermatogenesis
Summary
journal-article
Human testis-derived embryonic stem cell-like cells are not pluripotent, but possess potential of mesenchymal progenitors
Summary
journal-article
Correction: Spermatogonial stem cell sensitivity to capsaicin: An in vitro study
Summary
journal-article
Gene copy number reduction in the azoospermia factor c (AZFc) region and its effect on total motile sperm count
Summary
journal-article
In vitro propagation of human prepubertal spermatogonial stem cells
Summary
journal-article
A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis
Summary
journal-article
BMP4-induced differentiation of a rat spermatogonial stem cell line causes changes in its cell adhesion properties
Summary
journal-article
Embryonic stem cell-like cells derived from adult human testis
Summary
journal-article
Embryonic stem cell-like cells derived from adult human testis
Summary
journal-article
Y chromosome TSPY copy numbers and semen quality
Summary
journal-article
Propagation of human spermatogonial stem cells in vitro
Summary
journal-article
Proliferative activity in vitro and DNA repair indicate that adult mouse and human sertoli cells are not terminally differentiated, quiescent cells
Summary
journal-article
Expression of the pluripotency marker UTF1 is restricted to a subpopulation of early A spermatogonia in rat testis
Summary
journal-article
Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice
Summary
journal-article
Spermatogonial stem cell sensitivity to capsaicin: An in vitro study
Summary
journal-article
Role for Adhesion Molecules in the Spermatogonial Stem Cell Niche
Summary
journal-article
Mutations in the testis-specific NALP14 gene in men suffering from spermatogenic failure
Summary
journal-article
Gain-of-function amino acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia
Summary
journal-article
Spermatogonial stem cells: Characteristics and experimental possibilities
Summary
journal-article
LY6A/E (SCA-1) expression in the mouse testis
Summary
journal-article
Spermatogonial Stem Cell Biology
Summary
journal-article
Expression of the scaffolding subunit A of protein phosphatase 2A during rat testicular development
Summary
journal-article
Transplantation of germ cells from glial cell line-derived neurotrophic factor-overexpressing mice to host testes depleted of endogenous spermatogenesis by fractionated irradiation
Summary
journal-article
Establishment of cell lines with rat spermatogonial stem cell characteristics
Summary
journal-article
Maintenance of adult mouse type A spermatogonia in vitro: Influence of serum and growth factors and comparison with prepubertal spermatogonial cell culture
Summary
journal-article
Identification of candidate genes involved in gonocyte development
Summary
journal-article
Spermatogonial stem cell transplantation
Summary
journal-article
Spermatogonial stem cell transplantation
Published by
Molecular and Cellular Endocrinology
Summary
journal-article
Ontogeny of estrogen receptor-β expression in rat testis
Summary
journal-article
Differential expression of c-kit in mouse undifferentiated and differentiating type A spermatogonia
Summary
journal-article
Isolation and characterization of all-trans-retinoic acid-responsive genes in the rat testis
Summary
journal-article
Differential expression pattern of retinoid X receptors in adult murine testicular cells implies varying roles for these receptors in spermatogenesis
Summary
journal-article
The effect of 9-cis-retinoic acid on proliferation and differentiation of A spermatogonia and retinoid receptor gene expression in the vitamin A- deficient mouse testis
Summary
journal-article
Effect of retinoid status on the messenger ribonucleic acid expression of nuclear retinoid receptors α, β, and γ, and retinoid X receptors α, β, and γ in the mouse testis
Summary
journal-article
Immunomagnetic isolation of fetal rat gonocytes
Summary
journal-article
Isolation of the synchronized A spermatogonia from adult vitamin A- deficient rat testes
Summary
journal-article
Effect of vitamin A supplementation for 3 days on iron metabolism, liver function indicator enzymes and differential cell counts in bone marrow of rats with severe vitamin A deficiency
Summary
journal-article
Role of retinoids in differentiation and proliferation of spermatogenic cells
Summary
journal-article
All-trans-4-oxo-retinoic acid: A potent inducer of in vivo proliferation of growth-arrested a spermatogonia in the vitamin A-deficient mouse testis
Summary
journal-article
Characteristics of a spermatogonia and preleptotene spermatocytes in the vitamin A-deficient rat testis
Summary
journal-article
Expression of inhibin subunit mRNAs and inhibin levels in the testes of rats with stage-synchronized spermatogenesis
Summary
journal-article
Changes in retinoic acid receptor messenger ribonucleic acid levels in the vitamin A-deficient rat testis after administration of retinoids
Summary
journal-article
Characterization of the testicular cell types present in the rat by in vivo 31P magnetic resonance spectroscopy
Summary
journal-article
Retinoic acid is able to reinitiate spermatogenesis in vitamin A-deficient rats and high replicate doses support the full development of spermatogenic cells
Summary
journal-article
Synchronization of the seminiferous epithelium after vitamin A replacement in vitamin A-deficient mice
Summary
journal-article
A rapid immunogold-silver staining for detection of bromodeoxyuridine in large numbers of plastic sections, using microwave irradiation
Summary
journal-article
The origin of the synchronization of the seminiferous epithelium in vitamin A-deficient rats after vitamin A replacement
Summary
journal-article
Regulation of spermatogonial proliferation
Summary
journal-article
Isolation of gonadotrops from the pituitary of the African catfish, Clarias lazera - Morphological and physiological characterization of the purified cells
Summary
journal-article
Immunocytochemical labelling of isolated catfish pituitary gonadotrops with the protein A-gold method on epon sections
Summary
journal-article