Exploring the Conformational Changes and Dynamics of Mucins in Their Free State and in Complex with Mucin-Binding Proteins Using NMR
Summary
book-chapter
Francisco Corzana
Work
Universidad de La Rioja
|Full Professor
Spain
Education
Universidad de La Rioja
Spain
PhD in Chemistry
Universidad de La Rioja
Spain
Bachelor in Chemistry
Publications
Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies
Published by
Chemistry – A European Journal
Summary
journal-article
An organometallic approach to sub-2 nm thiolate-protected Au nanoclusters with enhanced catalytic and therapeutic properties
Published by
Nanoscale Advances
Summary
journal-article
Non‐Natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity
Published by
Angewandte Chemie International Edition
Summary
journal-article
Opposed Aromatic Surfaces Behave as Independent Binding Sites for Carbohydrate Stacking: Analysis of Sandwich-like CH/π/CH Complexes
Published by
JACS Au
Summary
journal-article
Detection of Tumor‐Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes
Published by
Angewandte Chemie
Summary
journal-article
Detection of Tumor‐Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes
Published by
Angewandte Chemie International Edition
Summary
journal-article
Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/π Complexes with Dynamic Covalent Glyco-Balances
Published by
JACS Au
Summary
journal-article
A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases
Published by
Nature Catalysis
Summary
journal-article
Author Correction: Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase
Published by
Nature Communications
Summary
journal-article
Exploring Photoredox Catalytic Reactions as an Entry to Glycosyl-α-amino Acids
Published by
ACS Omega
Summary
journal-article
Non‐Natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity
Published by
Angewandte Chemie
Summary
journal-article
Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase
Published by
Nature Communications
Summary
journal-article
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b
Published by
Nature Communications
Summary
journal-article
Turning universal O into rare Bombay type blood
Published by
Nature Communications
Summary
journal-article
Molecular Recognition of GalNAc in Mucin-Type O-Glycosylation
Published by
Accounts of Chemical Research
Summary
journal-article
Lipoyl-Based Antagonists of Transient Receptor Potential Cation A (TRPA1) Downregulate Osteosarcoma Cell Migration and Expression of Pro-Inflammatory Cytokines
Published by
ACS Pharmacology & Translational Science
Summary
journal-article
Towards Enantiomerically Pure Unnatural α-Amino Acids via Photoredox Catalytic 1,4-Additions to a Chiral Dehydroalanine
Published by
The Journal of Organic Chemistry
Summary
journal-article
Binding-driven reactivity attenuation enables NMR identification of selective drug candidates for nucleic acid targets
Published by
Communications Chemistry
Summary
journal-article
Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut
Published by
Nature Communications
Summary
journal-article
Synthesis of β2,2-Amino Acids by Stereoselective Alkylation of Isoserine Derivatives Followed by Nucleophilic Ring Opening of Quaternary Sulfamidates
Published by
The Journal of Organic Chemistry
Summary
journal-article
Structural basis for the synthesis of the core 1 structure by C1GalT1
Published by
Nature Communications
Summary
journal-article
Structure-based Design of Anti-cancer Vaccines: The Significance of Antigen Presentation to Boost the Immune Response
Published by
Current Medicinal Chemistry
Summary
journal-article
Toward Enantiomerically Pure β-Seleno-α-amino Acids via Stereoselective Se-Michael Additions to Chiral Dehydroalanines
Published by
Organic Letters
Summary
journal-article
Accelerating Reaction Rates of Biomolecules by Using Shear Stress in Artificial Capillary Systems
Published by
Journal of the American Chemical Society
Summary
journal-article
Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions
Published by
Bioconjugate Chemistry
Summary
journal-article
Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen
Published by
Biochemistry
Summary
journal-article
Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen
Published by
Biochemistry
Summary
journal-article
Efficient Amino‐Sulfhydryl Stapling on Peptides and Proteins Using Bifunctional NHS‐Activated Acrylamides
Published by
Angewandte Chemie
Summary
journal-article
Efficient Amino‐Sulfhydryl Stapling on Peptides and Proteins Using Bifunctional NHS‐Activated Acrylamides
Published by
Angewandte Chemie International Edition
Summary
journal-article
Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium
Published by
The Journal of Physical Chemistry Letters
Summary
journal-article
Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium
Published by
The Journal of Physical Chemistry Letters
Summary
journal-article
Fucosyltransferase-specific inhibition via next generation of fucose mimetics
Published by
Chemical Communications
Summary
journal-article
Fucosyltransferase-specific inhibition via next generation of fucose mimetics
Published by
Chemical Communications
Summary
journal-article
Dissecting the Essential Role of Anomeric β-Triflates in Glycosylation Reactions
Published by
Journal of the American Chemical Society
Summary
journal-article
Dissecting the Essential Role of Anomeric ß-Triflates in Glycosylation Reactions
Published by
Journal of the American Chemical Society
Summary
journal-article
Unveiling the activation dynamics of a fold-switch bacterial glycosyltransferase by 19F NMR
Published by
Journal of Biological Chemistry
Summary
journal-article
Unveiling the activation dynamics of a fold-switch bacterial glycosyltransferase by 19F NMR
Published by
Journal of Biological Chemistry
Summary
journal-article
Toward Enantiomerically Pure ß-Seleno-a-amino Acids via Stereoselective Se-Michael Additions to Chiral Dehydroalanines
Published by
Organic Letters
Summary
journal-article
Stable Pyrrole‐Linked Bioconjugates through Tetrazine‐Triggered Azanorbornadiene Fragmentation
Published by
Angewandte Chemie International Edition
Summary
journal-article
Stable Pyrrole‐Linked Bioconjugates through Tetrazine‐Triggered Azanorbornadiene Fragmentation
Published by
Angewandte Chemie
Summary
journal-article
Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation
Published by
Angewandte Chemie International Edition
Summary
journal-article
Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation
Published by
Angewandte Chemie
Summary
journal-article
Synthesis of Nβ-Substituted α,β-Diamino Acids via Stereoselective N-Michael Additions to a Chiral Bicyclic Dehydroalanine
Published by
The Journal of Organic Chemistry
Summary
journal-article
Synthesis of Nß-Substituted a,ß-Diamino Acids via Stereoselective N-Michael Additions to a Chiral Bicyclic Dehydroalanine
Published by
The Journal of Organic Chemistry
Summary
journal-article
Observation of the Unbiased Conformers of Putative DNA-Scaffold Ribosugars
Published by
ACS Central Science
Summary
journal-article
Observation of the Unbiased Conformers of Putative DNA-Scaffold Ribosugars
Published by
ACS Central Science
Summary
journal-article
Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase
Published by
Nature Communications
Summary
journal-article
Structural basis for substrate specificity and catalysis of a1,6-fucosyltransferase
Published by
Nature Communications
Summary
journal-article
Exploiting structure–activity relationships of QS-21 in the design and synthesis of streamlined saponin vaccine adjuvants
Published by
Chemical Communications
Summary
journal-article
Exploiting structureactivity relationships of QS-21 in the design and synthesis of streamlined saponin vaccine adjuvants
Published by
Chemical Communications
Summary
journal-article
Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands
Published by
Journal of Biological Chemistry
Summary
journal-article
Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Published by
Journal of the American Chemical Society
Summary
journal-article
Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/π and Cation/π Interactions for the Stabilization of Glycosyl-Oxocarbenium Ions
Published by
Journal of the American Chemical Society
Summary
journal-article
Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/p and Cation/p Interactions for the Stabilization of Glycosyl-Oxocarbenium Ions
Published by
Journal of the American Chemical Society
Summary
journal-article
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
Published by
Nature Protocols
Summary
journal-article
Efficient and irreversible antibodycysteine bioconjugation using carbonylacrylic reagents
Published by
Nature Protocols
Summary
journal-article
Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands
Published by
Journal of Biological Chemistry
Summary
journal-article
Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Published by
Journal of the American Chemical Society
Summary
journal-article
Tn Antigen Mimics by Ring-Opening of Chiral Cyclic Sulfamidates with Carbohydrate C1-S- and C1-O-Nucleophiles
Published by
The Journal of Organic Chemistry
Summary
journal-article
Cell‐Penetrating Peptides Containing Fluorescent d‐Cysteines
Published by
Chemistry – A European Journal
Summary
journal-article
Cell-Penetrating Peptides Containing Fluorescent d -Cysteines
Published by
Chemistry - A European Journal
Summary
journal-article
Tn Antigen Mimics by Ring-Opening of Chiral Cyclic Sulfamidates with Carbohydrate C1-S- and C1-O-Nucleophiles
Published by
The Journal of Organic Chemistry
Summary
journal-article
Enhanced Permeability and Binding Activity of Isobutylene‐Grafted Peptides
Published by
ChemBioChem
Summary
journal-article
Enhanced Permeability and Binding Activity of Isobutylene-Grafted Peptides
Published by
ChemBioChem
Summary
journal-article
Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor
Published by
Chemical Science
Summary
journal-article
Machine intelligence decrypts ß-lapachone as an allosteric 5-lipoxygenase inhibitor
Published by
Chemical Science
Summary
journal-article
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition
Published by
Journal of the American Chemical Society
Summary
journal-article
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition
Published by
Journal of the American Chemical Society
Summary
journal-article
Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation
Published by
Journal of the American Chemical Society
Summary
journal-article
Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation
Published by
Journal of the American Chemical Society
Summary
journal-article
The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences
Published by
Nature Communications
Summary
journal-article
The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences
Published by
Nature Communications
Summary
journal-article
Frontispiece: Site‐Selective Modification of Proteins with Oxetanes
Published by
Chemistry – A European Journal
Summary
journal-article
Frontispiece: Site-Selective Modification of Proteins with Oxetanes
Published by
Chemistry - A European Journal
Summary
journal-article
Site‐Selective Modification of Proteins with Oxetanes
Published by
Chemistry – A European Journal
Summary
journal-article
Site-Selective Modification of Proteins with Oxetanes
Published by
Chemistry - A European Journal
Summary
journal-article
Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides
Published by
Chemical Society Reviews
Summary
journal-article
Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides
Published by
Chemical Society Reviews
Summary
journal-article
The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
Published by
Journal of the American Chemical Society
Summary
journal-article
The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
Published by
Journal of the American Chemical Society
Summary
journal-article
Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
Published by
Nature Communications
Summary
journal-article
Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
Published by
Nature Communications
Summary
journal-article
A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2
Published by
Nature Chemical Biology
Summary
journal-article
A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2
Published by
Nature Chemical Biology
Summary
journal-article
A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2
Published by
Nature Chemical Biology
Summary
journal-article
Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S-Michael Addition
Published by
Organic Letters
Summary
journal-article
Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S-Michael Addition
Published by
Organic Letters
Summary
journal-article
Chondroitin Sulfate Tetrasaccharides: Synthesis, Three-Dimensional Structure and Interaction with Midkine
Published by
Chemistry (Weinheim an der Bergstrasse, Germany)
Summary
journal-article
Chondroitin Sulfate Tetrasaccharides: Synthesis, Three-Dimensional Structure and Interaction with Midkine
Published by
Chemistry (Weinheim an der Bergstrasse, Germany)
Summary
journal-article
Conformationally-locked C-glycosides: Tuning aglycone interactions for optimal chaperone behaviour in Gaucher fibroblasts
Published by
Organic and Biomolecular Chemistry
Summary
journal-article
Conformationally-locked C-glycosides: Tuning aglycone interactions for optimal chaperone behaviour in Gaucher fibroblasts
Published by
Organic and Biomolecular Chemistry
Summary
journal-article
Design of α-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety
Published by
Journal of Organic Chemistry
Summary
journal-article
Design of a-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety
Published by
Journal of Organic Chemistry
Summary
journal-article
Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders
Published by
Journal of the American Chemical Society
Summary
journal-article
Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders
Published by
Journal of the American Chemical Society
Summary
journal-article
Mucin architecture behind the immune response: design, evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment
Published by
Chemical Science
Summary
journal-article
Mucin architecture behind the immune response: Design, evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment
Published by
Chemical Science
Summary
journal-article
Mucin architecture behind the immune response: design, evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment
Published by
Chemical Science
Summary
journal-article
Quillaja saponin variants with central glycosidic linkage modifications exhibit distinct conformations and adjuvant activities
Published by
Chemical Science
Summary
journal-article
Quillaja saponin variants with central glycosidic linkage modifications exhibit distinct conformations and adjuvant activities
Published by
Chemical Science
Summary
journal-article
Tn Antigen Mimics Based on sp<sup>2</sup>-Iminosugars with Affinity for an anti-MUC1 Antibody
Published by
Organic Letters
Summary
journal-article
Tn Antigen Mimics Based on sp<sup>2</sup>-Iminosugars with Affinity for an anti-MUC1 Antibody
Published by
Organic Letters
Summary
journal-article
Unraveling the Conformational Landscape of Ligand Binding to Glucose/Galactose-Binding Protein by Paramagnetic NMR and MD Simulations
Published by
ACS Chemical Biology
Summary
journal-article
Unraveling the Conformational Landscape of Ligand Binding to Glucose/Galactose-Binding Protein by Paramagnetic NMR and MD Simulations
Published by
ACS Chemical Biology
Summary
journal-article
A thorough experimental study of CH/π interactions in water: quantitative structure-stability relationships for carbohydrate/aromatic complexes
Published by
Chemical Science
Summary
journal-article
A thorough experimental study of CH/π interactions in water: quantitative structure–stability relationships for carbohydrate/aromatic complexes
Published by
Chemical Science
Summary
journal-article
A thorough experimental study of CH/p interactions in water: quantitative structure-stability relationships for carbohydrate/aromatic complexes
Published by
Chemical Science
Summary
journal-article
A thorough experimental study of CH/p interactions in water: quantitative structurestability relationships for carbohydrate/aromatic complexes
Published by
Chemical Science
Summary
journal-article
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
Published by
Angewandte Chemie - International Edition
Summary
journal-article
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
Published by
Angewandte Chemie - International Edition
Summary
journal-article
Detection of tumor-associated glycopeptides by Lectins: The peptide context modulates carbohydrate recognition
Published by
ACS Chemical Biology
Summary
journal-article
Detection of tumor-associated glycopeptides by Lectins: The peptide context modulates carbohydrate recognition
Published by
ACS Chemical Biology
Summary
journal-article
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation
Published by
Nature Communications
Summary
journal-article
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation
Published by
Nature Communications
Summary
journal-article
Modulating Weak Interactions for Molecular Recognition: A Dynamic Combinatorial Analysis for Assessing the Contribution of Electrostatics to the Stability of CH-π Bonds in Water
Published by
Angewandte Chemie - International Edition
Summary
journal-article
Modulating Weak Interactions for Molecular Recognition: A Dynamic Combinatorial Analysis for Assessing the Contribution of Electrostatics to the Stability of CH-p Bonds in Water
Published by
Angewandte Chemie - International Edition
Summary
journal-article
New Insights into Molecular Recognition of Epitopes Related to MUC1 Human Mucin by Lectins [Tesis doctoral dirigida]
Summary
dissertation-thesis
Synthesis and conformational analysis of hybrid α/β-dipeptides incorporating S-glycosyl-β<sup>2,2</sup>-amino acids
Published by
Chemistry - A European Journal
Summary
journal-article
Synthesis of Mixed a/ß<sup>2,2</sup>-Peptides by Site-Selective Ring-Opening of Cyclic Quaternary Sulfamidates
Published by
Organic Letters
Summary
journal-article
Synthesis and conformational analysis of hybrid a/ß-dipeptides incorporating S-glycosyl-ß<sup>2,2</sup>-amino acids
Published by
Chemistry - A European Journal
Summary
journal-article
Synthesis of Mixed α/β<sup>2,2</sup>-Peptides by Site-Selective Ring-Opening of Cyclic Quaternary Sulfamidates
Published by
Organic Letters
Summary
journal-article
Conformational preferences of Chiral acyclic homooligomeric β2,2-Peptides
Published by
Current Topics in Medicinal Chemistry
Summary
journal-article
Conformational analysis of peptides and glycopeptides derived from the consensus sequence for β-O-glucosylation
Published by
Current Topics in Medicinal Chemistry
Summary
journal-article
Conformational analysis of peptides and glycopeptides derived from the consensus sequence for ß-O-glucosylation
Published by
Current Topics in Medicinal Chemistry
Summary
journal-article
Conformational preferences of Chiral acyclic homooligomeric ß2,2-Peptides
Published by
Current Topics in Medicinal Chemistry
Summary
journal-article
S-Michael additions to chiral dehydroalanines as an entry to glycosylated cysteines and a sulfa-tn antigen mimic
Published by
Journal of the American Chemical Society
Summary
journal-article
S-Michael additions to chiral dehydroalanines as an entry to glycosylated cysteines and a sulfa-tn antigen mimic
Published by
Journal of the American Chemical Society
Summary
journal-article
Serine versus threonine glycosylation with α-o-GalNac: Unexpected selectivity in their molecular recognition with lectins
Published by
Chemistry - A European Journal
Summary
journal-article
Serine versus threonine glycosylation with a-o-GalNac: Unexpected selectivity in their molecular recognition with lectins
Published by
Chemistry - A European Journal
Summary
journal-article
Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase 2
Published by
Angewandte Chemie - International Edition
Summary
journal-article
Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase 2
Published by
Angewandte Chemie - International Edition
Summary
journal-article
Síntesis y análisis conformacional de glicopéptidos que incorporan B-glucosa y a-N-acetylgalactosamina [Tesis doctoral dirigida]
Summary
dissertation-thesis
Synthesis and conformational analysis of neoglycoconjugates derived from O- and S-glucose
Published by
Carbohydrate Research
Summary
journal-article
Synthesis and conformational analysis of neoglycoconjugates derived from O- and S-glucose
Published by
Carbohydrate Research
Summary
journal-article
A double diastereoselective michael-type addition as an entry to conformationally restricted Tn antigen mimics
Published by
Journal of Organic Chemistry
Summary
journal-article
A dynamic combinatorial approach for the analysis of weak carbohydrate/aromatic complexes: Dissecting facial selectivity in CH/π stacking interactions
Published by
Journal of the American Chemical Society
Summary
journal-article
A double diastereoselective michael-type addition as an entry to conformationally restricted Tn antigen mimics
Published by
Journal of Organic Chemistry
Summary
journal-article
A dynamic combinatorial approach for the analysis of weak carbohydrate/aromatic complexes: Dissecting facial selectivity in CH/p stacking interactions
Published by
Journal of the American Chemical Society
Summary
journal-article
Chemical interrogation of drug/RNA complexes: From chemical reactivity to drug design
Published by
Angewandte Chemie - International Edition
Summary
journal-article
Chemical interrogation of drug/RNA complexes: From chemical reactivity to drug design
Published by
Angewandte Chemie - International Edition
Summary
journal-article
Conformations of the iduronate ring in short heparin fragments described by time-averaged distance restrained molecular dynamics
Published by
Glycobiology
Summary
journal-article
Conformations of the iduronate ring in short heparin fragments described by time-averaged distance restrained molecular dynamics
Published by
Glycobiology
Summary
journal-article
Diseño racional de derivados de mucina como candidatos a vacunas contra el cáncer [Tesis doctoral dirigida]
Summary
dissertation-thesis
Experimentando con las redes sociales en la enseñanza universitaria en ciencias
Published by
Revista Eureka sobre enseñanza y divulgación de las ciencias
Summary
journal-article
Size and shape assessment of organometallic gold(I) metallodendrimers through PGSE-NMR and molecular dynamics simulations
Published by
Inorganica Chimica Acta
Summary
journal-article
Cyclohexane ring as a tool to select the presentation of the carbohydrate moiety in glycosyl amino acids
Published by
Chemistry - A European Journal
Summary
journal-article
Cyclohexane ring as a tool to select the presentation of the carbohydrate moiety in glycosyl amino acids
Published by
Chemistry - A European Journal
Summary
journal-article
Multiple keys for a single lock: The unusual structural plasticity of the nucleotidyltransferase (4′)/kanamycin complex
Published by
Chemistry - A European Journal
Summary
journal-article
Multiple keys for a single lock: The unusual structural plasticity of the nucleotidyltransferase (4')/kanamycin complex
Published by
Chemistry - A European Journal
Summary
journal-article
On the study of the structure and dynamics of a carbohydrate of great biological importance: heparin
Published by
FEBS Journal
Summary
journal-article
Quaternary chiral β2,2-amino acids with pyridinium and imidazolium substituents
Published by
Chemistry - A European Journal
Summary
journal-article
Quaternary chiral ß2,2-amino acids with pyridinium and imidazolium substituents
Published by
Chemistry - A European Journal
Summary
journal-article
Size and shape assessment of organometallic gold(I) metallodendrimers through PGSE-NMR and molecular dynamics simulations
Published by
Inorganica Chimica Acta
Summary
journal-article
Molecular recognition of ß-O-GlcNAc glycopeptides by a lectin-like receptor: Binding modulation by the underlying ser or thr amino acids
Published by
ChemBioChem
Summary
journal-article
Accurate calculation of chemical shifts in highly dynamic H <inf>2</inf>@C<inf>60</inf> through an integrated quantum mechanics/molecular dynamics scheme
Published by
Organic Letters
Summary
journal-article
Accurate calculation of chemical shifts in highly dynamic H <inf>2</inf>@C<inf>60</inf> through an integrated quantum mechanics/molecular dynamics scheme
Published by
Organic Letters
Summary
journal-article
Engineering O-glycosylation points in non-extended peptides: Implications for the molecular recognition of short tumor-associated glycopeptides
Published by
Chemistry - A European Journal
Summary
journal-article
Engineering O-glycosylation points in non-extended peptides: Implications for the molecular recognition of short tumor-associated glycopeptides
Published by
Chemistry - A European Journal
Summary
journal-article
Molecular recognition of β-O-GlcNAc glycopeptides by a lectin-like receptor: Binding modulation by the underlying ser or thr amino acids
Published by
ChemBioChem
Summary
journal-article
Rational design of a Tn antigen mimic
Published by
Chemical Communications
Summary
journal-article
Rational design of a Tn antigen mimic
Published by
Chemical Communications
Summary
journal-article
The use of time-averaged 3JHH Restrained molecular dynamics (tar-MD) simulations for the conformational analysis of five-membered ring systems: Methodology and applications
Published by
Journal of Computational Chemistry
Summary
journal-article
The use of time-averaged 3JHH Restrained molecular dynamics (tar-MD) simulations for the conformational analysis of five-membered ring systems: Methodology and applications
Published by
Journal of Computational Chemistry
Summary
journal-article
Antimicrobial Peptides and Their Superior Fluorinated Analogues: Structure-Activity Relationships as Revealed by NMR Spectroscopy and MD Calculations
Published by
ChemBioChem
Summary
journal-article
Cyclobutane amino acid analogues of furanomycin obtained by a formal [2 + 2] cycloaddition strategy promoted by methylaluminoxane
Published by
Journal of Organic Chemistry
Summary
journal-article
Cyclobutane amino acid analogues of furanomycin obtained by a formal [2 + 2] cycloaddition strategy promoted by methylaluminoxane
Published by
Journal of Organic Chemistry
Summary
journal-article
Dynamics and hydration properties of small antifreeze-like glycopeptides containing non-natural amino acids
Published by
European Journal of Organic Chemistry
Summary
journal-article
Dynamics and hydration properties of small antifreeze-like glycopeptides containing non-natural amino acids
Published by
European Journal of Organic Chemistry
Summary
journal-article
Role of aromatic rings in the molecular recognition of aminoglycoside antibiotics: Implications for drug design
Published by
Journal of the American Chemical Society
Summary
journal-article
Role of aromatic rings in the molecular recognition of aminoglycoside antibiotics: Implications for drug design
Published by
Journal of the American Chemical Society
Summary
journal-article
Structure-based design of highly crowded ribostamycin/kanamycin hybrids as a new family of antibiotics
Published by
Chemistry - A European Journal
Summary
journal-article
Structure-based design of highly crowded ribostamycin/kanamycin hybrids as a new family of antibiotics
Published by
Chemistry - A European Journal
Summary
journal-article
Antimicrobial Peptides and Their Superior Fluorinated Analogues: Structure-Activity Relationships as Revealed by NMR Spectroscopy and MD Calculations
Published by
ChemBioChem
Summary
journal-article
The unusual nucleotide recognition properties of the resistance enzyme ANT(4′): Inorganic Tri/polyphosphate as a substrate for aminoglycoside inactivation
Published by
Chemistry - A European Journal
Summary
journal-article
The unusual nucleotide recognition properties of the resistance enzyme ANT(4'): Inorganic Tri/polyphosphate as a substrate for aminoglycoside inactivation
Published by
Chemistry - A European Journal
Summary
journal-article
Stabilizing unusual conformations in small peptides and glucopeptides using a hydroxylated cyclobutane amino acid
Published by
Organic and Biomolecular Chemistry
Summary
journal-article
The nature and sequence of the amino acid aglycone strongly modulates the conformation and dynamics effects of Tn antigen's clusters
Published by
Chemistry - A European Journal
Summary
journal-article
Beta-O-Glicosilación de péptidos que incorporan aminoácidos no naturales. [Tesis doctoral dirigida]
Summary
dissertation-thesis
Conformational effects of the non-natural α-methylserine on small peptides and glycopeptides
Published by
Journal of Organic Chemistry
Summary
journal-article
Conformational effects of the non-natural a-methylserine on small peptides and glycopeptides
Published by
Journal of Organic Chemistry
Summary
journal-article
Insights into the geometrical features underlying β-O-GIcNAc glycosylation: Water pockets drastically modulate the interactions between the carbohydrate and the peptide backbone
Published by
Chemistry - A European Journal
Summary
journal-article
Insights into the geometrical features underlying ß-O-GIcNAc glycosylation: Water pockets drastically modulate the interactions between the carbohydrate and the peptide backbone
Published by
Chemistry - A European Journal
Summary
journal-article
Role of conserved salt bridges in homeodomain stability and DNA binding
Published by
Journal of Biological Chemistry
Summary
journal-article
Role of conserved salt bridges in homeodomain stability and DNA binding
Published by
Journal of Biological Chemistry
Summary
journal-article
The nature and sequence of the amino acid aglycone strongly modulates the conformation and dynamics effects of Tn antigen's clusters
Published by
Chemistry - A European Journal
Summary
journal-article
Stabilizing unusual conformations in small peptides and glucopeptides using a hydroxylated cyclobutane amino acid
Published by
Organic and Biomolecular Chemistry
Summary
journal-article
NMR-based analysis of aminoglycoside recognition by the resistance enzyme ANT(4′): The pattern of OH/NH3+ substitution determines the preferred antibiotic binding mode and is critical for drug inactivation
Published by
Journal of the American Chemical Society
Summary
journal-article
Glicopéptidos Modelo que incorporan el antígeno Tn. Síntesis y análisis conformacional [Tesis doctoral dirigida]
Summary
dissertation-thesis
NMR-based analysis of aminoglycoside recognition by the resistance enzyme ANT(4'): The pattern of OH/NH3+ substitution determines the preferred antibiotic binding mode and is critical for drug inactivation
Published by
Journal of the American Chemical Society
Summary
journal-article
Non-natural amino acids as modulating agents of the conformational space of model glycopeptides.
Published by
Chemistry (Weinheim an der Bergstrasse, Germany)
Summary
journal-article
Non-natural amino acids as modulating agents of the conformational space of model glycopeptides.
Published by
Chemistry (Weinheim an der Bergstrasse, Germany)
Summary
journal-article
Nuevas aportaciones al estudio estructural de glicopéptidos
Published by
Anales Real Sociedad Española de Química
Summary
journal-article
Solution structures of chemoenzymatically synthesized heparin and its precursors
Published by
Journal of the American Chemical Society
Summary
journal-article
Solution structures of chemoenzymatically synthesized heparin and its precursors
Published by
Journal of the American Chemical Society
Summary
journal-article
The pattern of distribution of amino groups modulates the structure and dynamics of natural aminoglycosides: Implications for RNA recognition
Published by
Journal of the American Chemical Society
Summary
journal-article
A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition: Dramatic alterations in the neomycin-B protonation state upon binding to a 23-mer RNA aptamer
Published by
Chemical Communications
Summary
journal-article
A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition: Dramatic alterations in the neomycin-B protonation state upon binding to a 23-mer RNA aptamer
Published by
Chemical Communications
Summary
journal-article
Serine versus threonine glycosylation: The methyl group causes a drastic alteration on the carbohydrate orientation and on the surrounding water shell
Published by
Journal of the American Chemical Society
Summary
journal-article
Serine versus threonine glycosylation: The methyl group causes a drastic alteration on the carbohydrate orientation and on the surrounding water shell
Published by
Journal of the American Chemical Society
Summary
journal-article
The pattern of distribution of amino groups modulates the structure and dynamics of natural aminoglycosides: Implications for RNA recognition
Published by
Journal of the American Chemical Society
Summary
journal-article
Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance
Published by
Journal of the American Chemical Society
Summary
journal-article
New insights into α-GalNAc-Ser motif: Influence of hydrogen bonding versus solvent interactions on the preferred conformation
Published by
Journal of the American Chemical Society
Summary
journal-article
Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance
Published by
Journal of the American Chemical Society
Summary
journal-article
New insights into a-GalNAc-Ser motif: Influence of hydrogen bonding versus solvent interactions on the preferred conformation
Published by
Journal of the American Chemical Society
Summary
journal-article
Effect of ß-O-glucosylation on L-Ser and L-Thr diamides: A bias toward a-helical conformations
Published by
Chemistry - A European Journal
Summary
journal-article
Conformational analysis of 2-substituted cyclobutane-α-amino acid derivatives. A synergistic experimental and computational study
Published by
Journal of Organic Chemistry
Summary
journal-article
Conformational analysis of 2-substituted cyclobutane-a-amino acid derivatives. A synergistic experimental and computational study
Published by
Journal of Organic Chemistry
Summary
journal-article
Effect of β-O-glucosylation on L-Ser and L-Thr diamides: A bias toward α-helical conformations
Published by
Chemistry - A European Journal
Summary
journal-article
Molecular recognition of aminoglycoside antibiotics by bacterial defence proteins: NMR study of the structural and conformational features of streptomycin inactivation by Bacillus subtilis aminoglycoside-6-adenyl transferase
Published by
Chemistry - A European Journal
Summary
journal-article
SN2 vs E2 on quaternary centers: An easy approach to chiral ß2,2-amino acids from cyclic sulfamidates
Published by
Phosphorus, Sulfur and Silicon and the Related Elements
Summary
journal-article
A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4
Published by
Journal of the American Chemical Society
Summary
journal-article
A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4
Published by
Journal of the American Chemical Society
Summary
journal-article
Diastereoselective synthesis of (S)- and (R)-α-phenylserine by a sulfinimine-mediated strecker reaction
Published by
Synthesis
Summary
journal-article
Diastereoselective synthesis of (S)- and (R)-a-phenylserine by a sulfinimine-mediated strecker reaction
Published by
Synthesis
Summary
journal-article
Limited flexibility of lactose detected from residual dipolar couplings using molecular dynamics simulations and steric alignment methods
Published by
Journal of the American Chemical Society
Summary
journal-article
Limited flexibility of lactose detected from residual dipolar couplings using molecular dynamics simulations and steric alignment methods
Published by
Journal of the American Chemical Society
Summary
journal-article
Molecular recognition of aminoglycoside antibiotics by bacterial defence proteins: NMR study of the structural and conformational features of streptomycin inactivation by Bacillus subtilis aminoglycoside-6-adenyl transferase
Published by
Chemistry - A European Journal
Summary
journal-article
SN2 vs E2 on quaternary centers: An easy approach to chiral β2,2-amino acids from cyclic sulfamidates
Published by
Phosphorus, Sulfur and Silicon and the Related Elements
Summary
journal-article
SN2 vs. E2 on quaternary centres: An application to the synthesis of enantiopure ß2,2-amino acids
Published by
Chemical Communications
Summary
journal-article
A Hydration Study of (1→4) and (1→6) Linked α-Glucans by Comparative 10 ns Molecular Dynamics Simulations and 500-MHz NMR
Published by
Journal of Computational Chemistry
Summary
journal-article
A Hydration Study of (1¿4) and (1¿6) Linked a-Glucans by Comparative 10 ns Molecular Dynamics Simulations and 500-MHz NMR
Published by
Journal of Computational Chemistry
Summary
journal-article
Hydration of the amylopectin branch point. Evidence of restricted conformational diversity of the α-(1→6) linkage
Published by
Journal of the American Chemical Society
Summary
journal-article
Hydration of the amylopectin branch point. Evidence of restricted conformational diversity of the a-(1¿6) linkage
Published by
Journal of the American Chemical Society
Summary
journal-article
New syntheses of enantiopure 2-methyl isoserines
Published by
Tetrahedron Asymmetry
Summary
journal-article
New syntheses of enantiopure 2-methyl isoserines
Published by
Tetrahedron Asymmetry
Summary
journal-article
SN2 vs. E2 on quaternary centres: An application to the synthesis of enantiopure β2,2-amino acids
Published by
Chemical Communications
Summary
journal-article
α-Methylserinals as an access to α-methyl-β-hydroxyamino acids: Application in the synthesis of all stereoisomers of α- methylthreonine
Published by
Tetrahedron Asymmetry
Summary
journal-article
a-Methylserinals as an access to a-methyl-ß-hydroxyamino acids: Application in the synthesis of all stereoisomers of a- methylthreonine
Published by
Tetrahedron Asymmetry
Summary
journal-article
Understanding the unusual regioselectivity in the nucleophilic ring-opening reactions of gem-disubstituted cyclic sulfates. Experimental and theoretical studies
Published by
Journal of Organic Chemistry
Summary
journal-article
Conformational analysis of N-Boc-N,O-isopropylidene-a-serinals. A combined DFT and NMR study
Published by
Tetrahedron
Summary
journal-article
Conformational analysis of N-Boc-N,O-isopropylidene-α-serinals. A combined DFT and NMR study
Published by
Tetrahedron
Summary
journal-article
Diastereoselective synthesis of protected 4-epi-vancosamine from (S)-N-Boc-N,O-isopropylidene-α-methylserinal
Published by
Tetrahedron Asymmetry
Summary
journal-article
Diastereoselective synthesis of protected 4-epi-vancosamine from (S)-N-Boc-N,O-isopropylidene-a-methylserinal
Published by
Tetrahedron Asymmetry
Summary
journal-article
Understanding the unusual regioselectivity in the nucleophilic ring-opening reactions of gem-disubstituted cyclic sulfates. Experimental and theoretical studies
Published by
Journal of Organic Chemistry
Summary
journal-article
(S)- and (R)-N-Boc-N,O-isopropylidene-alfa-methylserinals. Preparation and synthetic applications
Published by
Acros Organics Acta
Summary
journal-article
Solution structure of two xenoantigens: aGal-LacNAc and aGal-Lewis X
Published by
Glycobiology
Summary
journal-article
Asymmetric hetero Diels-Alder as an access to carbacephams
Published by
Journal of Organic Chemistry
Summary
journal-article
Asymmetric hetero Diels-Alder as an access to carbacephams
Published by
Journal of Organic Chemistry
Summary
journal-article
Preparation and Synthetic Applications of (S)- and (R)-N-Boc-N,O-Isopropylidene-alfa-methylserinals
Published by
Targets in Heterocyclic Systems
Summary
book-chapter
Solution structure of two xenoantigens: αGal-LacNAc and αGal-Lewis X
Published by
Glycobiology
Summary
journal-article
Preparación y aplicaciones sintéticas de N-Boc-N,O-isopropilidenserinales enantioméricamente puros [Tesis doctoral]
Summary
dissertation-thesis
Enantioselective synthesis of (S)- and (R)-α-methylserines: Application to the synthesis of (S)- and (R)-N-Boc-N,O-isopropylidene-α-methylserinals
Published by
Tetrahedron Asymmetry
Summary
journal-article
Enantioselective synthesis of (S)- and (R)-a-methylserines: Application to the synthesis of (S)- and (R)-N-Boc-N,O-isopropylidene-a-methylserinals
Published by
Tetrahedron Asymmetry
Summary
journal-article
Asymmetric synthesis of all isomers of α-methyl-β-phenylserine
Published by
Tetrahedron Asymmetry
Summary
journal-article
Asymmetric synthesis of all isomers of a-methyl-ß-phenylserine
Published by
Tetrahedron Asymmetry
Summary
journal-article
Preparation and synthetic applications of (S)- and (R)-N-boc-N, O- isopropylidene-a-methylserinals: Asymmetric synthesis of (S)- and (R)-2- amino-2-methylbutanoic acids (Iva)
Published by
Journal of Organic Chemistry
Summary
journal-article
Preparation and synthetic applications of (S)- and (R)-N-boc-N, O- isopropylidene-α-methylserinals: Asymmetric synthesis of (S)- and (R)-2- amino-2-methylbutanoic acids (Iva)
Published by
Journal of Organic Chemistry
Summary
journal-article
Convenient procedures for the synthesis of N-BOC-D-serinal acetonide from L-serine
Published by
Synthesis
Summary
journal-article
Convenient procedures for the synthesis of N-BOC-D-serinal acetonide from L-serine
Published by
Synthesis
Summary
journal-article