Laura Martinez Gili

About

Postdoctoral Research Fellow, Imperial College London

Work

Imperial College London
|

Research Fellow

United Kingdom of Great Britain and Northern Ireland

Imperial College London
|

Postdoctoral Research Associate

United Kingdom of Great Britain and Northern Ireland

Publications

Author Correction: Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Published by

Nature Medicine

Summary

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Disruption of gut barrier integrity and host-microbiome interactions underlie MASLD severity in patients with type-2 diabetes mellitus.

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Gut microbes

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Diet shapes the metabolite profile in the intact human ileum, which affects PYY release.

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Science translational medicine

Summary

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Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Published by

Nature Medicine

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Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide.

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Nature communications

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Potential therapeutic implications of histidine catabolism by the gut microbiota in NAFLD patients with morbid obesity.

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Cell reports. Medicine

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Bacterial and metabolic phenotypes associated with inadequate response to ursodeoxycholic acid treatment in primary biliary cholangitis

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Gut Microbes

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Editorial: the acid test-can bile acids predict recurrence of Clostridioides difficile infection? Authors' reply.

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Alimentary pharmacology & therapeutics

Summary

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Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality

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JACC: Heart Failure

Summary

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Fecal bile acid profiles predict recurrence in patients with primary Clostridioides difficile infection

Summary

preprint

Assessing the clinical value of faecal bile acid profiling to predict recurrence in primary Clostridioides difficile infection

Published by

Alimentary Pharmacology & Therapeutics

Summary

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Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.

Published by

Gut

Summary

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The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota.

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Microbiome

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An integrated workflow for enhanced taxonomic and functional coverage of the mouse fecal metaproteome

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Gut Microbes

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Combinatorial, additive and dose-dependent drug-microbiome associations.

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Nature

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Accuracy of citrulline, I-FABP and D-lactate in the diagnosis of acute mesenteric ischemia.

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Scientific reports

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Modulation of the Gut Microbiota by Olive Oil Phenolic Compounds: Implications for Lipid Metabolism, Immune System, and Obesity

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Nutrients

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Understanding the mechanisms of efficacy of fecal microbiota transplant in treating recurrent Clostridioides difficile infection and beyond: the contribution of gut microbial-derived metabolites

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Gut Microbes

Summary

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An Integrated Workflow for Enhanced Taxonomic and Functional Coverage of the Mouse Faecal Metaproteome

Summary

preprint

Diet-induced metabolic changes of the human gut microbiome: importance of short-chain fatty acids, methylamines and indoles.

Published by

Acta diabetologica

Summary

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The translational regulator FMRP controls lipid and glucose metabolism in mice and humans.

Published by

Molecular metabolism

Summary

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Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Published by

Nature medicine

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Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control

Summary

preprint

Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Published by

Nature medicine

Summary

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Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.

Summary

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The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading.

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Redox biology

Summary

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Fatty Liver Disease: A Crosstalk Between Lipid Species

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European Medical Journal

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Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells.

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Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer.

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Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy.

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Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis.

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Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking.

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ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.

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ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.

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Caffeine stimulates hepatic lipid metabolism via autophagy-lysosomal pathway.

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APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease.

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Targeting cholesterol at different levels in the mevalonate pathway protects fatty liver against ischemia-reperfusion injury.

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Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.

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