Polycomb repressive complex 2 is critical for mouse cortical glutamatergic neuron development.
Published by
Cerebral cortex (New York, N.Y. : 1991)
Summary
journal-article
Rodrigo Suárez
About
I am a biologist interested in the general question of how changes in developmental processes can lead to evolutionary variation and origin of complex traits (such as neural circuits). I study development and evolution of the brain of mammals. My doctoral thesis studied brain regions involved in olfactory and pheromonal communication in mammals. I discovered several events of parallel co-variation of sensory pathways in distantly related species sharing similar ecological niches, as cases of ontogenetic and phylogenetic plasticity. Currently, I study development and evolution of neocortical circuits by following two main lines of research: one aims to determine how early neuronal activity affects development of cortical circuits, and the other one aims to understand what developmental processes led to the evolution of the mammalian brain, including the origin of the corpus callosum exclusively in Eutherians, but not in monotreme or marsupial mammals, and the evolution of the neocortex in mammals but not in other vertebrates. My research combines molecular development (electroporation, CRISPR), transcriptomics, sensory manipulations, neuroanatomy mapping (MRI, stereotaxic tracer injections, confocal and image analysis), optogenetics, and in vivo calcium imaging in rodent pups and marsupial joeys.
Work
The University of Queensland
|Associate Professor
Australia
→
The University of Queensland
|Senior Lecturer
Australia
→
The University of Queensland
|UQ Amplify Research Fellow
Australia
→
The University of Queensland
|ARC DECRA Research Fellow
Australia
→
The University of Queensland
|Postdoctoral Research Fellow
Australia
→
Education
University of Chile
Chile
→
PhD in Biomedical Sciences
University of Chile
Chile
→
Bachelor in Science m/ Biology
Publications
Brain plasticity following corpus callosum agenesis or loss: a review of the Probst bundles
Published by
Frontiers in Neuroanatomy
Summary
journal-article
Non-uniform temporal scaling of developmental processes in the mammalian cortex
Published by
Nature Communications
Summary
journal-article
Clade-specific forebrain cytoarchitectures of the extinct Tasmanian tiger
Published by
Proceedings of the National Academy of Sciences
Summary
journal-article
Cortical activity emerges in region-specific patterns during early brain development
Published by
Proceedings of the National Academy of Sciences
Summary
journal-article
Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes
Published by
Development
Summary
journal-article
Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes.
Published by
Development (Cambridge, England)
Summary
journal-article
Evolution of Developmental Timing as a Driving Force of Brain Diversity
Published by
Brain, Behavior and Evolution
Summary
journal-article
DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation.
Published by
eLife
Summary
journal-article
The evolution, formation and connectivity of the anterior commissure.
Published by
Seminars in cell & developmental biology
Summary
journal-article
DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation
Published by
eLife
Summary
journal-article
DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation.
Published by
eLife
Summary
journal-article
Bilateral visual projections exist in non-teleost bony fish and predate the emergence of tetrapods
Published by
Science
Summary
journal-article
Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution
Published by
Proceedings of the National Academy of Sciences
Summary
journal-article
In Search Of Common Developmental And Evolutionary Origin Of The Claustrum And Subplate.
Published by
The Journal of Comparative Neurology
Summary
journal-article
Shared and differential features of Robo3 expression pattern in amniotes
Published by
Journal of Comparative Neurology
Summary
journal-article
A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum
Published by
Proceedings of the National Academy of Sciences
Summary
journal-article
Multiple events of gene manipulation via in pouch electroporation in a marsupial model of mammalian forebrain development
Published by
Journal of Neuroscience Methods
Summary
journal-article
Transcriptional control of long-range cortical projections
Published by
Current Opinion in Neurobiology
Summary
journal-article
Development of body, head and brain features in the Australian fat-tailed dunnart (Sminthopsis crassicaudata; Marsupialia: Dasyuridae); A postnatal model of forebrain formation
Published by
PLOS ONE
Summary
journal-article
Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals
Published by
Neural Development
Summary
journal-article
The anatomy, organisation and development of contralateral callosal projections of the mouse somatosensory cortex
Published by
Brain and Neuroscience Advances
Summary
journal-article
Evolution of Telencephalic Commissures: Conservation and Change of Developmental Systems in the Origin of Brain Wiring Novelties
Published by
Evolution of Nervous Systems
Summary
other
Evolution of telencephalic commissures: Conservation and change of developmental systems in the origin of brain wiring novelties
Published by
Evolution of Nervous Systems
Summary
book-chapter
Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum
Published by
Cell Reports
Summary
journal-article
Astroglial-mediated remodeling of the interhemispheric midline is required for the formation of the corpus callosum
Published by
Cell Reports
Summary
journal-article
Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum
Published by
Neuron
Summary
journal-article
Cognitive ecology in hummingbirds: The role of sexual dimorphism and its anatomical correlates on memory
Published by
PLoS ONE
Summary
journal-article
Evolution and development of interhemispheric connections in the vertebrate forebrain
Published by
Frontiers in Human Neuroscience
Summary
journal-article
Thalamic afferents and neocortical arealization: An ongoing journey
Published by
Journal of Neuroscience
Summary
journal-article
Mutual influences between the main olfactory and vomeronasal systems in development and evolution
Published by
Frontiers in Neuroanatomy
Summary
journal-article
Mutual influences between the main olfactory and vomeronasal systems in development and evolution
Published by
Frontiers in Neuroanatomy
Summary
journal-article
Deterioration of the Gαo vomeronasal pathway in sexually dimorphic mammals
Published by
PLoS ONE
Summary
journal-article
Molecular switches in the development and fate specification of vomeronasal neurons
Published by
Journal of Neuroscience
Summary
journal-article
Shared and differential traits in the accessory olfactory bulb of caviomorph rodents with particular reference to the semiaquatic capybara
Published by
Journal of Anatomy
Summary
journal-article
Heterogeneities of size and sexual dimorphism between the subdomains of the lateral-innervated accessory olfactory bulb (AOB) of Octodon degus (Rodentia: Hystricognathi)
Published by
Behavioural Brain Research
Summary
journal-article
Transposition and intermingling of Gαi2 and Gαo afferences into single vomeronasal glomeruli in the Madagascan lesser tenrec Echinops telfairi
Published by
PLoS ONE
Summary
journal-article
Undergraduate teaching of evolution in chile: more than natural selection
Published by
Revista chilena de historia natural
Summary
journal-article
Undergraduate teaching of evolution in Chile: More than natural selection
Published by
Revista Chilena de Historia Natural
Summary
journal-article