Developed a comprehensive Python toolkit, "Galen-Kit," integrating modules for ETL, EDA, ML, and reporting, streamlining genomic workflows and data analysis.
Engineered and deployed "Galen-CLI," a command-line interface, significantly enhancing the efficiency of bioinformatic pipeline execution for research teams.
Analyzed large-scale transcriptomic and clinical datasets (TCGA, CGGA, Exsegen) using differential expression, PCA, and pathway enrichment to classify Oligodendroglioma subgroups.
Built and validated machine learning models that accurately predict unknown sample subgroups, advancing precision in cancer classification and diagnostic capabilities.
Processed 763 clinical samples and over 18,000 methylation probes to identify four distinct Medulloblastoma molecular subtypes, facilitating targeted therapeutic strategies.
Constructed robust ML models utilizing methylation profiles, ensuring high performance and reliability through rigorous validation techniques for molecular variant identification.