Selim Ait-Aissa

Work

Institut National de l'Environnement Industriel et des Risques

France

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Publications

Inter-laboratory validation study of an in vitro glucocorticoid receptor transactivation assay for testing potential endocrine disrupting chemicals

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Toxicology in Vitro

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In vitro assessment of aryl hydrocarbon, estrogen, and androgen receptor-mediated activities of secondary organic aerosols formed from the oxidation of polycyclic aromatic hydrocarbons and furans

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Environmental Research

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New insights into the regulation of cyp3a65 expression in transgenic tg(cyp3a65:GFP) zebrafish embryos

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Aquatic Toxicology

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Metabolic disrupting chemicals in the intestine: the need for biologically relevant models

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FEBS Open Bio

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Insights into secondary organic aerosol formation from the day- and nighttime oxidation of polycyclic aromatic hydrocarbons and furans in an oxidation flow reactor

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Atmospheric Chemistry and Physics

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Interlaboratory prevalidation of a new in vitro transcriptional activation assay for the screening of (anti-)androgenic activity of chemicals using the UALH-hAR cell line

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Toxicology in Vitro

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Biological effect and chemical monitoring of Watch List substances in European surface waters: Steroidal estrogens and diclofenac - Effect-based methods for monitoring frameworks.

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Environment international

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Estrogenicity of chemical mixtures revealed by a panel of bioassays.

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The Science of the total environment

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Human and Zebrafish Nuclear Progesterone Receptors Are Differently Activated by Manifold Progestins

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Environmental Science & Technology

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Estrogenic activity of surface waters using zebrafish- and human-based in vitro assays: The Danube as a case-study

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Environmental Toxicology and Pharmacology

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Estrogenic activity of surface waters using zebrafish- and human-based in vitro assays: The Danube as a case-study

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Environmental Toxicology and Pharmacology

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Chronic simultaneous exposure of common carp (Cyprinus carpio) from embryonic to juvenile stage to drospirenone and gestodene at low ng/L level caused intersex

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Ecotoxicology and Environmental Safety

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Let us empower the WFD to prevent risks of chemical pollution in European rivers and lakes

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Environmental Sciences Europe

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Strengthen the European collaborative environmental research to meet European policy goals for achieving a sustainable, non-toxic environment

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Environmental Sciences Europe

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Differential activity of BPA, BPAF and BPC on zebrafish estrogen receptors in vitro and in vivo

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Toxicology and Applied Pharmacology

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Monitoring estrogenic activities of waste and surface waters using a novel in vivo zebrafish embryonic (EASZY) assay: Comparison with in vitro cell-based assays and determination of effect-based trigger values

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Environment International

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Combined effects of environmental xeno-estrogens within multi-component mixtures: Comparison of in vitro human- and zebrafish-based estrogenicity bioassays

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Chemosphere

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Effect-based methods are key. The European Collaborative Project SOLUTIONS recommends integrating effect-based methods for diagnosis and monitoring of water quality

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Environmental Sciences Europe

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Future water quality monitoring: improving the balance between exposure and toxicity assessments of real-world pollutant mixtures

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Environmental Sciences Europe

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An integrative approach combining passive sampling, bioassays, and effect-directed analysis to assess the impact of wastewater effluent

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Environmental Toxicology and Chemistry

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Effect-based and chemical analytical methods to monitor estrogens under the European Water Framework Directive

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Trac-Trends in Analytical Chemistry

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Effect-based monitoring of the Danube River using mobile passive sampling

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Science of the Total Environment

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Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive

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Science of the Total Environment

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European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters (vol 601, pg 1849, 2017)

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Science of the Total Environment

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Liver histopathology and biochemical biomarkers in Gobius niger and Zosterisessor ophiocephalus from polluted and non-polluted Tunisian lagoons (Southern Mediterranean Sea)

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Marine Pollution Bulletin

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Mixture Concentration-Response Modeling Reveals Antagonistic Effects of Estradiol and Genistein in Combination on Brain Aromatase Gene (cyp19a1b) in Zebrafish

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International Journal of Molecular Sciences

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Mixture effects in samples of multiple contaminants - An inter-laboratory study with manifold bioassays

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Environment International

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Photodegradation of novel oral anticoagulants under sunlight irradiation in aqueous matrices

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Chemosphere

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Screening and risk management solutions for steroidal estrogens in surface and wastewater

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Trac-Trends in Analytical Chemistry

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Solid-phase extraction as sample preparation of water samples for cell-based and other in vitro bioassays

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Environmental Science-Processes & Impacts

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Triclosan Lacks (Anti-) Estrogenic Effects in Zebrafish Cells but Modulates Estrogen Response in Zebrafish Embryos

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International Journal of Molecular Sciences

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Assessment of a novel device for onsite integrative large-volume solid phase extraction of water samples to enable a comprehensive chemical and effect-based analysis

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Science of the Total Environment

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Comparison of the In Vivo Biotransformation of Two Emerging Estrogenic Contaminants, BP2 and BPS, in Zebrafish Embryos and Adults

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International Journal of Molecular Sciences

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Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their Contribution to effects in surface water

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Water Research

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Effect-based tools for monitoring estrogenic mixtures: Evaluation of five in vitro bioassays

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Water Research

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European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters

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Science of the Total Environment

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In vitro and in vivo estrogenic activity of BPA, BPF and BPS in zebrafish-specific assays

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Ecotoxicology and Environmental Safety

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Integrating chemical analysis and bioanalysis to evaluate the contribution of wastewater effluent on the micropollutant burden in small streams

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Science of the Total Environment

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Seasonal rhythm of physiological indexes, liver protein level, and biotransformation biomarkers in Zosterisessor ophiocephalus and Gobius niger from a low contaminated lagoon (Ghar El Melh lagoon, Tunisia)

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Biological Rhythm Research

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Additive effects of levonorgestrel and ethinylestradiol on brain aromatase (cyp19a1b) in zebrafish specific in vitro and in vivo bioassays

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Toxicology and Applied Pharmacology

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Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring

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Water Research

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Effect-directed analysis supporting monitoring of aquatic environments - An in-depth overview

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Science of the Total Environment

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Evaluation of an extraction method for a mixture of endocrine disrupters in sediment using chemical and in vitro biological analyses

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Environmental Science and Pollution Research

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Photodegradation of fluorene in aqueous solution: Identification and biological activity testing of degradation products

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Journal of Chromatography a

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Proposal to optimize ecotoxicological evaluation of wastewater treated by conventional biological and ozonation processes

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Environmental Science and Pollution Research

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Spatial and temporal variation of biochemical biomarkers in Gobius niger (Gobiidae) from a southern Mediterranean lagoon (Bizerta lagoon, Tunisia): Influence of biotic and abiotic factors

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Marine Pollution Bulletin

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Zebrafish-based reporter gene assays reveal different estrogenic activities in river waters compared to a conventional human-derived assay

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Science of the Total Environment

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BFCOD activity in fish cell lines and zebrafish embryos and its modulation by chemical ligands of human aryl hydrocarbon and nuclear receptors

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Environmental Science and Pollution Research

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Cell-Specific Biotransformation of Benzophenone-2 and Bisphenol-S in Zebrafish and Human in Vitro Models Used for Toxicity and Estrogenicity Screening

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Environmental Science & Technology

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Future water quality monitoring - Adapting tools to deal with mixtures of pollutants in water resource management

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Science of the Total Environment

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Linking in Vitro Effects and Detected Organic Micropollutants in Surface Water Using Mixture-Toxicity Modeling

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Environmental Science & Technology

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Affinity Purification Using Recombinant PXR as a Tool to Characterize Environmental Ligands

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Environmental Toxicology

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Identification of Synthetic Steroids in River Water Downstream from Pharmaceutical Manufacture Discharges Based on a Bioanalytical Approach and Passive Sampling

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Environmental Science & Technology

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Mixtures of Chemical Pollutants at European Legislation Safety Concentrations: How Safe Are They?

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Toxicological Sciences

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Photolysis of estrone generates estrogenic photoproducts with higher activity than the parent compound

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Environmental Science and Pollution Research

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Selectivity of natural, synthetic and environmental estrogens for zebrafish estrogen receptors

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Toxicology and Applied Pharmacology

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Characterization of endocrine disruptors from a complex matrix using estrogen receptor affinity columns and high performance liquid chromatography-high resolution mass spectrometry

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Environmental Science and Pollution Research

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Distribution of steroid- and dioxin-like activities between sediments, POCIS and SPMD in a French river subject to mixed pressures

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Environmental Science and Pollution Research

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Effect-directed analysis of endocrine-disrupting compounds in multi-contaminated sediment: identification of novel ligands of estrogen and pregnane X receptors

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Analytical and Bioanalytical Chemistry

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Estrogenic Potency of Benzophenone UV Filters in Breast Cancer Cells: Proliferative and Transcriptional Activity Substantiated by Docking Analysis

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Plos One

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Using mass spectrometry to highlight structures of degradation compounds obtained by photolysis of chloroacetamides: Case of acetochlor

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Journal of Chromatography a

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In vitro biomonitoring of contamination by estrogenic compounds in coastal environments: Comments on the use of M. galloprovincialis

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Environmental Toxicology

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Occurrence of androgens in sewage treatment plants influents is associated with antagonist activities on other steroid receptors

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Water Research

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Selective Activation of Zebrafish Estrogen Receptor Subtypes by Chemicals by Using Stable Reporter Gene Assay Developed in a Zebrafish Liver Cell Line

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Toxicological Sciences

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Adverse effects in wild fish living downstream from pharmaceutical manufacture discharges

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Environment International

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Androgen receptor binding affinity: a QSAR evaluation

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Sar and Qsar in Environmental Research

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Characterization of testicular expression of P450 17 alpha-hydroxylase, 17,20-lyase in zebrafish and its perturbation by the pharmaceutical fungicide clotrimazole

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General and Comparative Endocrinology

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New challenges in environmental analytical chemistry: Identification of toxic compounds in complex mixtures

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Comptes Rendus Chimie

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Passive samplers for chemical substance monitoring and associated toxicity assessment in water

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Water Science and Technology

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Anti-androgenic activities of environmental pesticides in the MDA-kb2 reporter cell line

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Toxicology in Vitro

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Bioanalytical characterisation of multiple endocrine- and dioxin-like activities in sediments from reference and impacted small rivers

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Environmental Pollution

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Endocrine disruption in wild populations of chub (Leuciscus cephalus) in contaminated French streams

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Science of the Total Environment

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Evaluation of an hPXR reporter gene assay for the detection of aquatic emerging pollutants: screening of chemicals and application to water samples

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Analytical and Bioanalytical Chemistry

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Impact of Urban Wastewater Discharges on the Sediments of a Small Mediterranean River and Associated Coastal Environment: Assessment of Estrogenic and Dioxin-like Activities

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Archives of Environmental Contamination and Toxicology

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Monitoring organic contaminants in small French coastal lagoons: comparison of levels in mussel, passive sampler and sediment

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Journal of Environmental Monitoring

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A stable fish reporter cell line to study estrogen receptor transactivation by environmental (xeno)estrogens

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Toxicology in Vitro

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Brain and gonadal aromatases as molecular and biochemical targets of endocrine disrupters in a model species, the zebralish (Danio rerio)

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Cybium

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Effect of (xeno)-estrogens on zebrafish P450c17 (C17,17 alpha-hydroxylase/17,20-lyase) mRNA and protein expression in gonadal tissue

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Cybium

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Extraction and purification procedures for simultaneous quantification of phenolic xenoestrogens and steroid estrogens in river sediment by gas chromatography/ion trap mass spectrometry

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Rapid Communications in Mass Spectrometry

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Monitoring of dioxin-like, estrogenic and anti-androgenic activities in sediments of the Bizerta lagoon (Tunisia) by means of in vitro cell-based bioassays: Contribution of low concentrations of polynuclear aromatic hydrocarbons (PAHs)

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Science of the Total Environment

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Profiling of benzophenone derivatives using fish and human estrogen receptor-specific in vitro bioassays

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Toxicology and Applied Pharmacology

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Study of the chemical derivatization of zearalenone and its metabolites for gas chromatography-mass spectrometry analysis of environmental samples

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Journal of Chromatography a

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Preliminary investigation of multi-biomarker responses in three-spined stickleback (Gasterosteus aculeatus L.) sampled in contaminated streams

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Ecotoxicology

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Biochemical effects of nonylphenol polyethoxylate adjuvant, Diquat herbicide and their mixture on the three-spined stickleback (Gasterosteus aculeatus L.)

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Marine Environmental Research

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Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line

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Toxicology

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Binding of estrogenic compounds to recombinant estrogen receptor-alpha: Application to environmental analysis

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Environmental Health Perspectives

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Copper-induced oxidative stress in three-spined stickleback: relationship with hepatic metal levels

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Environmental Toxicology and Pharmacology

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Assessment of estrogen (ER) and aryl hydrocarbon receptor (AhR) mediated activities in organic sediment extracts of the Detroit River, using in vitro bioassays based on human MELN and teleost PLHC-1 cell lines

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Journal of Great Lakes Research

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Effects of human pharmaceuticals on cytotoxicity, EROD activity and ROS production in fish hepatocytes

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Toxicology

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Biomarker responses in juvenile rainbow trout (Oncorhynchus mykiss) after single and combined exposure to low doses of cadmium, zinc, PCB77 and 17 beta-oestradiol

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Biomarkers

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Evaluation of an in vitro hsp70 induction test for toxicity assessment of complex mixtures: comparison with chemical analyses and ecotoxicity tests

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Ecotoxicology and Environmental Safety

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Biotransformation of phenylurea herbicides by a soil bacterial strain, Arthrobacter sp N2: structure, ecotoxicity and fate of diuron metabolite with soil fungi

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Chemosphere

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Isolation, characterization and diuron transformation capacities of a bacterial strain Arthrobacter sp N2

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Chemosphere

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Activation of the hsp70 promoter by environmental inorganic and organic chemicals: relationships with cytotoxicity and lipophilicity

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Toxicology

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Induction of the hsp70 gene promoter by various anticancer drugs

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Toxicology in Vitro

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Use of the CaCo-2 model in the screening of polluting substance toxicity

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Toxicology in Vitro

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Use of transepithelial electrical resistance in the study of pentachlorophenol toxicity

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Toxicology in Vitro

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