Shaurya Prakash

Ph.D. Candidate & Research Scientist in Molecular and Fungal Biology
Mahendragarh, IN.

About

A highly accomplished Ph.D. candidate and research scientist with expertise in Molecular Biology, Fungal Biology, and Computational Biology, leveraging advanced techniques in microbial characterization, assay development, and machine learning. Proven ability to drive significant research outcomes, evidenced by 22 publications (cumulative IF 45.8), successful mentorship of 10 Master's and Ph.D. scholars, and recognition as "Best Student Researcher 2024." Seeking to apply advanced scientific inquiry and analytical skills to impactful R&D roles in biotechnology or pharmaceutical research.

Work

Central University of Haryana
|

Ph.D. Researcher

Mahendragarh, Haryana, India

Summary

Led comprehensive Ph.D. research focusing on the molecular characterization of Echinocandin B synthesis in Aspergillus nidulans, contributing to advanced understanding of fungal biology and secondary metabolites.

Highlights

Conducted in-depth molecular characterization of Echinocandin B synthesis in *Aspergillus nidulans*, utilizing advanced genomic and proteomic techniques to identify key genetic pathways.

Published 22 research outputs (10 articles, 4 reviews, 8 book chapters) with a cumulative impact factor of 45.8, demonstrating significant contributions to the scientific community.

Mentored 10 Master's and new Ph.D. scholars in molecular biology and cell culture research, fostering academic growth and contributing to institutional research capacity.

Awarded "Best Student Researcher 2024" by Central University of Haryana for outstanding publication record and research impact.

Developed and optimized experimental protocols for fungal cultivation, gene expression analysis, and metabolite extraction, enhancing research efficiency and data quality.

Central University of South Bihar
|

Master's Researcher

Gaya, Bihar, India

Summary

Performed master's dissertation research on the characterization of *Vibrio cholerae O139* serogroup, focusing on biofilm formation and antibiotic resistance mechanisms.

Highlights

Characterized *Vibrio cholerae O139* serogroup, investigating biofilm formation and antibiotic resistance patterns to inform public health strategies.

Applied advanced microbiological techniques to analyze bacterial growth kinetics, biofilm architecture, and susceptibility to various antimicrobial agents.

Contributed to understanding critical virulence factors and potential therapeutic targets for *Vibrio cholerae* infections.

Jawaharlal Nehru University
|

Summer Intern

New Delhi, Delhi, India

Summary

Conducted research on the cytotoxic effects of streptozotocin on mice pancreatic beta cell lines, contributing to diabetes research.

Highlights

Investigated the cytotoxic effects of streptozotocin on mice pancreatic beta cell lines, providing insights into diabetes pathogenesis and potential therapeutic interventions.

Utilized cell culture techniques, viability assays, and microscopic analysis to assess cellular responses and quantify damage.

Collaborated effectively with senior researchers to design experiments, execute protocols, and interpret complex biological data.

Mahavir Cancer Sansthan
|

Research Trainee

Patna, Bihar, India

Summary

Gained practical experience in biochemical assays and bio-instrumentation, supporting cancer research initiatives.

Highlights

Executed various biochemical assays, including enzyme kinetics and protein quantification, to support ongoing cancer research projects.

Operated and maintained advanced bio-instrumentation, ensuring accurate data collection and experimental reliability.

Acquired foundational skills in laboratory safety protocols, quality control measures, and data documentation within a research setting.

Education

Central University of Haryana
Mahendragarh, Haryana, India

Ph.D.

Biochemistry

Courses

Molecular Biology

Fungal Biology

Fermentation Biology

Secondary Metabolites

Machine Learning

Computational Biology

Systems Pharmacology

Central University of South Bihar
Gaya, Bihar, India

M.Sc.

Biotechnology

Grade: 8.65 CGPA

Courses

Microbiology

Molecular Biology

Biochemical Techniques

Genetic Engineering

Bioinformatics

College of Commerce, Arts, and Science
Patna, Bihar, India

B.Sc.

Biotechnology

Grade: 73.25%

Courses

General Biology

Chemistry

Physics

Biostatistics

Environmental Science

Awards

Best Student Researcher

Awarded By

Central University of Haryana

Recognized for an outstanding publication record of 22 research outputs with a cumulative impact factor of 45.8, demonstrating significant contributions to scientific literature.

Publications

In-silico and functional characterization of EcdLp, an ABC transporter of Aspergillus nidulans NRRL11440.

Published by

Current Microbiology

Summary

Prakash, S., Kumar, A., Kumari, H., Sinha, M., Kumar, V., & Kumar, A. (2026). In-silico and functional characterization of EcdLp, an ABC transporter of Aspergillus nidulans NRRL11440. Current Microbiology (I.F. 2.6)

Development of CuO-enhanced soybean protein isolate biofilms with antioxidant, photocatalytic, and antimicrobial properties for food packaging applications.

Published by

Next Materials

Summary

Dhayal, A., Kumar, H., Kumar, G., Prakash, S., Yadav, A., & Brahma, M. (2025). Development of CuO-enhanced soybean protein isolate biofilms with antioxidant, photocatalytic, and antimicrobial properties for food packaging applications. Next Materials, 8, 100616. 10.1016/j.nxmate.2025.100616 (I.F. NA)

Design, synthesis, characterization, and exploration of biological potential of new thiazole-pyrazolone hybrids.

Published by

Journal of Molecular Structure

Summary

Kumar, A., Kumar, M., Brahma, M., Prakash, S., Kumar, A., Maruthi, M., Ansari, A., Singh, S., Kataria, R., & Kumar, V. (2025). Design, synthesis, characterization, and exploration of biological potential of new thiazole-pyrazolone hybrids. Journal of Molecular Structure, 1348 (1), 143296. 10.1016/j.molstruc.2025.143296 (I.F. 4.7)

Silver nanoparticles synthesis from Bacillus subtilis and its ROS-mediated staphylocidal activity against methicillin-resistant Staphylococcus aureus.

Published by

Journal of Basic Microbiology

Summary

Sinha, M., Kumari, H., Prakash, S., Kumari, N., Maruthi, M., Arora, K., & Kumar, A. (2025). Silver nanoparticles synthesis from Bacillus subtilis and its ROS-mediated staphylocidal activity against methicillin-resistant Staphylococcus aureus. Journal of Basic Microbiology. 10.1002/jobm.70091 (I.F. 2.7)

Unveiling Gelation and Antimicrobial Potentials of α-Acyloxy Carboxamides: Findings from Experimental and Theoretical Approach.

Published by

ChemMedChem

Summary

Sebastian, S., Kumar, M., Hussain, F., Rathore, S., Rohila, Y., Meenakshi, Prakash, S., Kumar, A., Bhardwaj, P., & Maruthi, M. (2025). Unveiling Gelation and Antimicrobial Potentials of α-Acyloxy Carboxamides: Findings from Experimental and Theoretical Approach. ChemMedChem, 20(8), e202400774. 10.1002/cmdc.202400774 (I.F. 3.4)

Alchemy of Fungi and AI: Response surface methodology and Artificial neural network-based optimization of Echinocandin B production in Aspergillus nidulans.

Published by

Biotechnology and Applied Biochemistry

Summary

Prakash, S., Sahu, N., Choudhary, A., Kumari, H., Sinha, M., Mahanty, B., & Kumar, A. (2025). Alchemy of Fungi and AI: Response surface methodology and Artificial neural network-based optimization of Echinocandin B production in Aspergillus nidulans. Biotechnology and Applied Biochemistry, 1–42. 10.1002/bab.2787 (I.F. 2.8)

Unravelling the potential of 2-(Bromo/polybromophenylamino) substituted-4-arylthiazoles: Synthesis, characterization, anticancer, antimicrobial, molecular docking and ADMET studies.

Published by

Journal of Molecular Structure

Summary

Kumar, A., Brahma, M., Prakash, S., Kumar, A., Maruthi, M., Kumar, M., Ansari, A., Kataria, R., & Kumar, V. (2025). Unravelling the potential of 2-(Bromo/polybromophenylamino) substituted-4-arylthiazoles: Synthesis, characterization, anticancer, antimicrobial, molecular docking and ADMET studies. Journal of Molecular Structure, 1351(2), 144301. 10.1016/j.molstruc.2025.144301 (I.F. 4.7)

Regulation and Induction of Fungal Secondary Metabolites: A Comprehensive Review.

Published by

Archives of Microbiology

Summary

Prakash, S., Kumari, H., Minakshi, & Kumar, A. (2025). Regulation and Induction of Fungal Secondary Metabolites: A Comprehensive Review. Archives of Microbiology, 207(189). 10.1007/s00203-025-04386-0 (I.F. 2.6)

Therapeutic outcome of secondary metabolites against contagious and noncontagious human diseases.

Published by

Academic Press (Elsevier)

Summary

Sinha, M., Kumari, H., Prakash, S., & Kumar, A. (2025). Therapeutic outcome of secondary metabolites against contagious and noncontagious human diseases. In Secondary Metabolites in Stress and Disease Management (pp.519), Academic Press (Elsevier). 10.1016/B978-0-443-33959-2.00007-1

Starch/Whey protein isolate/TiO2 bio-nanocomposite based film: Sustainable alternative to non-biodegradable plastic.

Published by

Next Materials

Summary

Dhayal, A., Kumar, H., Sharma, R., Kumari, R., Kumar, G., Saloni, Yadav, A., Yadav, A., Prakash, S., & Kumar, A. Starch/Whey protein isolate/TiO2 bio-nanocomposite - based film: Sustainable alternative to non-biodegradable plastic. Next Materials (Revision Submitted).

Micellplex mediated site-specific RNAi delivery: An insight to plausible therapeutic intervention against COVID-19.

Published by

Coronaviruses

Summary

Prakash, S., Minakshi, Kumari, H., Ajay, A.K., & Kumar, A. (2024). Micellplex mediated site-specific RNAi delivery: An insight to plausible therapeutic intervention against COVID-19, Coronaviruses; 6(3). 10.2174/0126667975314555240805115442 (I.F. NA)

Atom-economical synthesis, antimicrobial assessment, and molecular dynamics of indole-derived peptidomimetics for improved therapeutic insights.

Published by

Journal of Molecular Structure

Summary

Sebastian, S., Rohila, Y., Meenakshi, Prakash, S., Kumar, A., Sengupta, S., Kumar, D., Ansari, A., & Gupta, M. K. (2024). Atom-economical synthesis, antimicrobial assessment, and molecular dynamics of indole-derived peptidomimetics for improved therapeutic insights. Journal of Molecular Structure, 1318 (P2), 139211. 10.1016/j.molstruc.2024.139211 (I.F. 4.7)

Development of starch/whey protein isolate biofilm incorporated with silver oxide nanoparticles: A multifunctional antioxidant, antibacterial, photocatalytic, and anticancer agent.

Published by

Inorganic Chemistry Communications

Summary

Dhayal, A., Kumar, H., Prakash, S., Kumar, A., Brahma, M., & Maruthi, M. (2024). Development of starch/whey protein isolate biofilm incorporated with silver oxide nanoparticles: A multifunctional antioxidant, antibacterial, photocatalytic, and anticancer agent. Inorganic Chemistry Communications, 171, 113661. 10.1016/j.inoche.2024.113661 (I.F. 5.4)

Environmentally benign self-assembled biopolymer-peptoid nanosilver composite hybrid gel beads via ion-crosslinking for antimicrobial and catalytic applications.

Published by

Applied Materials Today

Summary

Sebastian, S., Rohila, Y., Ansari, A., Prakash, S., Kumar, A., & Gupta, M. K. (2024). Environmentally benign self-assembled biopolymer-peptoid nanosilver composite hybrid gel beads via ion-crosslinking for antimicrobial and catalytic applications. Applied Materials Today, 41, 102512. 10.1016/j.apmt.2024.102512 (I.F. 6.9)

Dysbiosis and Regulation of Gut Microbiota in Type 2 Diabetes Mellitus.

Published by

Current Pharmaceutical Biotechnology

Summary

Minakshi, Kumari, H., Prakash, S., & Kumar, A. (2024). Dysbiosis and Regulation of Gut Microbiota in Type 2 Diabetes Mellitus. Current Pharmaceutical Biotechnology; 26(14), 2288-2309. 10.2174/0113892010318580240910061534 (I.F. 2.6)

Dual Role of 2-Deoxy-D-Glucose in Seizure Modulation.

Published by

Bentham Science

Summary

Prakash, S., Singh, K., & Kumar, A. (2024). Dual Role of 2-Deoxy-D-Glucose in Seizure Modulation. In 2-Deoxy-D-Glucose: Chemistry and Biology (pp. 232). Bentham Science. 10.2174/9789815305159124010014

Farnesol-mediated activation of ecd gene cluster elevates Echinocandin B synthesis in Aspergillus nidulans.

Published by

Antonie Van Leeuwenhoek

Summary

Prakash, S., Choudhary, A., Kumari, H., Sinha, M., Kumar, V., & Kumar, A. Farnesol-mediated activation of ecd gene cluster elevates Echinocandin B synthesis in Aspergillus nidulans. Antonie Van Leeuwenhoek (Revision Submitted).

The Evolution of Next-Generation Lateral Flow Assays for Bacterial and Fungal Diagnostics.

Published by

Microchimica Acta

Summary

Prakash, S., Mishra, C., Sinha, M., Kumari, H., & Kumar, A. The Evolution of Next-Generation Lateral Flow Assays for Bacterial and Fungal Diagnostics. Microchimica Acta (Under Review).

Epigenetic Regulation of Fungal Secondary Metabolites for the Enhancement of Therapeutically Active Compounds.

Published by

Springer, Singapore

Summary

Prakash, S., Kumari, H., Minakshi, & Kumar, A. (2024). Epigenetic Regulation of Fungal Secondary Metabolites for the Enhancement of Therapeutically Active Compounds. In Fungi Bioactive Metabolites: Integration of Pharmaceutical Applications (pp. 605). Springer, Singapore. 10.1007/978-981-99-5696-8_19

Unraveling the Intricacies of Carbon Catabolic Repression and Glucose in Fungal Pathogenesis.

Published by

CRC Press

Summary

Prakash, S., Kumari, H., Minakshi, Pasrija, R., & Kumar, A. (2024). Unraveling the Intricacies of Carbon Catabolic Repression and Glucose in Fungal Pathogenesis. Human Fungal Diseases (pp. 169), CRC Press. 10.1201/9781032642864-13

Antiviral Potential of 2-DG Used in Different Viral Infections.

Published by

Bentham Science

Summary

Prakash, S., Minakshi, Kumari, H., & Kumar, A. (2024). Antiviral Potential of 2-DG Used in Different Viral Infections. In 2-Deoxy-D-Glucose: Chemistry and Biology (pp.70), Bentham Science. 10.2174/9789815305159124010008

Strategies for Enhancing the Production of Echinocandin.

Published by

Springer, Singapore

Summary

Kumari, H.*, Prakash, S.*, Minakshi, & Kumar, A. (2024). Strategies for Enhancing the Production of Echinocandin. In Fungi Bioactive Metabolites: Integration of Pharmaceutical Applications (pp. 633). Springer, Singapore. 10.1007/978-981-99-5696-8_20

Nanotechnology: An Advanced Approach toward the Treatment of Fungal Infections.

Published by

CRC Press

Summary

Kumari, H., Prakash, S., Pasrija, R., & Kumar, A. (2024). Nanotechnology: An Advanced Approach toward the Treatment of Fungal Infections. In Human Fungal Diseases (pp. 155). CRC Press. 10.1201/9781032642864-12

Natural Bioactive Products from Marine Fungi Against Bacterial Infection.

Published by

Springer, Singapore

Summary

Minakshi, Prakash, S., Kumari, H., & Kumar, A. (2024). Natural Bioactive Products from Marine Fungi Against Bacterial Infection. In Fungi Bioactive Metabolites: Integration of Pharmaceutical Applications (pp. 241). Springer, Singapore. 10.1007/978-981-99-5696-8_8

Long chain α-acyloxy carboxamides as potential antimicrobial agents.

Published by

Indian Patent Office

Summary

Gupta, M.K., Sebastian, S., Rohila, Y., Kumar, V., Ansari, A., Prakash, S., Kumar, A. Long chain α-acyloxy carboxamides as potential antimicrobial agents. Indian Patent, Filed on 19.10.2023 (Application No.: IN 202311071514), Published on 24.02.2023.

Mucormycosis threats: A systemic review.

Published by

Journal of Basic Microbiology

Summary

Prakash, S., & Kumar, A. (2023). Mucormycosis threats: A systemic review. Journal of Basic Microbiology, 63(2), 119–127. 10.1002/jobm.202200334 (I.F. 2.7)

Skills

Technical Skills

Microbial isolation, Microbial culture, Microbial characterization, Antimicrobial evaluation, Assay development, Molecular biology, Machine learning, Structural biology, Fungal Biology, Fermentation Biology, Secondary Metabolites, Computational Biology, Systems Pharmacology, Genomic Analysis, Proteomic Techniques, Cell Culture, Bio-instrumentation.

Soft Skills

Communication, Problem solving, Mentorship, Team collaboration, Research Training, Scientific Writing, Experimental Design, Data Analysis, Critical Thinking.

References

Prof. Antresh Kumar

Professor, Central University of Haryana, Haryana, India. Phone: +91-7766932922; Email: antreshkumar@gamil.com, antreshkumar@cuh.ac.in

Prof. Rajendra Prasad

Dean and Director, Amity Institute of Biotechnology, Amity University, Panchgaon, Manesar, Haryana, India. Phone: +91-9810974443; Email: rp47jnu@gmail.com

Dr. Biswanath Mahanty

Associate Professor, Division of Biotechnology, Karunya Institute of Technology & Sciences, Coimbatore, Tamil Nadu, India. Phone: +91-8016747093; Email: bmahanty@karunya.edu

Dr. Mulaka Maruthi

Assistant Professor, Central University of Haryana, Haryana, India. Phone: +91-6305763257; Email: mulaka@cuh.ac.in