Simon Cleary

Work

King's College London

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Lecturer

United Kingdom of Great Britain and Northern Ireland

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University of California San Francisco

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Postdoctoral Scholar

US

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Babraham Institute

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Postdoctoral Research Scientist

United Kingdom of Great Britain and Northern Ireland

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Education

King's College London

United Kingdom of Great Britain and Northern Ireland
→
PhD

King's College London

United Kingdom of Great Britain and Northern Ireland
→
Physiology & Pharmacology BSc

Publications

In Vivo Measurement of Granzyme Proteolysis from Activated Immune Cells with PET

ACS Central Science

journal-article

Impact of chronic hyperglycaemia on the coronary microcirculation - benefits of targeting IL-36 and diet reversal

Basic Research in Cardiology

journal-article

Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche

preprint

Collecting lymphatics unzip to drain injured lungs

Nature Cardiovascular Research

journal-article

Collecting lymphatics unzip to drain injured lungs

Nature Cardiovascular Research

journal-article

Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer

Journal of Experimental Medicine

journal-article

Decoding functional hematopoietic progenitor cells in the adult human lung

Blood

journal-article

Imaging lung lymphatics in action in metastatic cancer

Nature Reviews Cancer

journal-article

Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer

bioRxiv : the preprint server for biology

working-paper

CD94 + natural killer cells potentiate pulmonary ischaemia-reperfusion injury

European Respiratory Journal

journal-article

CD94+natural killer cells potentiate pulmonary ischaemia–reperfusion injury

European Respiratory Journal

journal-article

Reply: The importance of disrupting complement activation in acute lung injury

Journal of Clinical Investigation

journal-article

Reply: The importance of disrupting complement activation in acute lung injury

Journal of Clinical Investigation

journal-article

Imaging the Granzyme Mediated Host Immune Response to Viral and Bacterial Pathogens In Vivo Using Positron Emission Tomography

ACS Infectious Diseases

journal-article

G6b-B antibody-based cis-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics

preprint

IgG hexamers initiate complement-dependent acute lung injury

Journal of Clinical Investigation

journal-article

Loss of neutrophil Shp1 produces hemorrhagic and lethal acute lung injury

bioRxiv

working-paper

IgG hexamers initiate acute lung injury

preprint

Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in the lung and kidney of sickle cell mice

preprint

Decoding functional hematopoietic progenitor cells in the adult human lung

preprint

TNIK: A redox sensor in endothelial cell permeability

Science Advances

journal-article

Tnik

Science Advances

journal-article

Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury

Journal of Clinical Investigation

journal-article

Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury

The Journal of clinical investigation

journal-article

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

preprint

Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer

preprint

Optimizing anesthesia and delivery approaches for dosing into lungs of mice

preprint

Investigating and imaging platelets in inflammation

International Journal of Biochemistry and Cell Biology

journal-article

Imaging inflammation

Progress in Inflammation Research

book

Optimizing anesthesia and delivery approaches for dosing into lungs of mice

American Journal of Physiology-Lung Cellular and Molecular Physiology

journal-article

CCR5 drives NK cell–associated airway damage in pulmonary ischemia-reperfusion injury

JCI Insight

journal-article

ADAM8 signaling drives neutrophil migration and ARDS severity

JCI Insight

journal-article

Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression

Journal of Clinical Investigation

journal-article

Lung megakaryocytes are immune modulatory cells

Journal of Clinical Investigation

journal-article

The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection

Blood Advances

journal-article

Red Blood Cells Elicit Platelet-Dependent Neutrophil Recruitment Into Lung Airspaces

Shock

journal-article

Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3

American Journal of Respiratory Cell and Molecular Biology

journal-article

β2M Signals Monocytes Through Non-Canonical TGFβ Receptor Signal Transduction

Circulation Research

journal-article

Chewing the fat on TRALI

Blood

journal-article

Natural killer cells activated through NKG2D mediate lung ischemia-reperfusion injury

Journal of Clinical Investigation

journal-article

Global absence and targeting of protective immune states in severe COVID-19

Nature

journal-article

Global absence and targeting of protective immune states in severe COVID-19

Nature

journal-article

Global absence and targeting of protective immune states in severe COVID-19

Nature

journal-article

Animal models of mechanisms of SARS‐CoV‐2 infection and COVID‐19 pathology

British Journal of Pharmacology

journal-article

Global Absence and Targeting of Protective Immune States in Severe COVID-19

bioRxiv : the preprint server for biology

working-paper

Global absence and targeting of protective immune states in severe COVID-19.

bioRxiv

other

Update on animal models for COVID‐19 research

British Journal of Pharmacology

journal-article

Global Absence and Targeting of Protective Immune States in Severe COVID-19.

preprint

Complement activation on endothelium initiates antibody-mediated acute lung injury

Journal of Clinical Investigation

journal-article

Complement activation on endothelium initiates antibody-mediated acute lung injury

Journal of Clinical Investigation

journal-article

Radiolabelling and immunohistochemistry reveal platelet recruitment into lungs and platelet migration into airspaces following LPS inhalation in mice

Journal of Pharmacological and Toxicological Methods

journal-article

Radiolabelling and immunohistochemistry reveal platelet recruitment into lungs and platelet migration into airspaces following LPS inhalation in mice

Journal of Pharmacological and Toxicological Methods

journal-article

Pharmacological strategies for targeting platelet activation in asthma

Current Opinion in Pharmacology

journal-article

Mitochondrial DNA Stimulates TLR9-Dependent NET Formation in Primary Graft Dysfunction

American Journal of Respiratory Cell and Molecular Biology

journal-article

LPS-Induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-selectin.

American journal of respiratory cell and molecular biology

journal-article

LPS-induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-Selectin

American Journal of Respiratory Cell and Molecular Biology

journal-article

Sensory nerves mediate spontaneous behaviors in addition to inflammation in a murine model of psoriasis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

journal-article

Platelet Depletion Impairs Host Defense to Pulmonary Infection with Pseudomonas aeruginosa in Mice

American Journal of Respiratory Cell and Molecular Biology

journal-article

Platelets Play a Central Role in Sensitization to Allergen.

American Journal of Respiratory Cell and Molecular Biology

journal-article

Gustav Born: pioneer in imaging platelet and leukocyte biology

Platelets

journal-article

Lipopolysaccharide (LPS) induced pulmonary neutrophil recruitment and platelet activation is mediated via the P2Y 1 and P2Y 14 receptors in mice

Pulmonary Pharmacology & Therapeutics

journal-article

The application of local hypobaric pressure - A novel means to enhance macromolecule entry into the skin.

Journal of Controlled Release

journal-article

The application of local hypobaric pressure - A novel means to enhance macromolecule entry into the skin.

journal-article

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation

Blood

journal-article

Exploring dual PDE3/4 inhibition in the treatment of airway diseases

Drugs of the Future

journal-article

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.

journal-article

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.

Blood

journal-article