In Vivo Measurement of Granzyme Proteolysis from Activated Immune Cells with PET
Published by
ACS Central Science
Summary
journal-article
Work
King's College London
|Lecturer
United Kingdom of Great Britain and Northern Ireland
→
University of California San Francisco
|Postdoctoral Scholar
US
→
Babraham Institute
|Postdoctoral Research Scientist
United Kingdom of Great Britain and Northern Ireland
→
Education
King's College London
United Kingdom of Great Britain and Northern Ireland
→
PhD
King's College London
United Kingdom of Great Britain and Northern Ireland
→
Physiology & Pharmacology BSc
Publications
Impact of chronic hyperglycaemia on the coronary microcirculation - benefits of targeting IL-36 and diet reversal
Published by
Basic Research in Cardiology
Summary
journal-article
Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
Summary
preprint
Collecting lymphatics unzip to drain injured lungs
Published by
Nature Cardiovascular Research
Summary
journal-article
Collecting lymphatics unzip to drain injured lungs
Published by
Nature Cardiovascular Research
Summary
journal-article
Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer
Published by
Journal of Experimental Medicine
Summary
journal-article
Decoding functional hematopoietic progenitor cells in the adult human lung
Published by
Blood
Summary
journal-article
Imaging lung lymphatics in action in metastatic cancer
Published by
Nature Reviews Cancer
Summary
journal-article
Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer
Published by
bioRxiv : the preprint server for biology
Summary
working-paper
CD94 + natural killer cells potentiate pulmonary ischaemia-reperfusion injury
Published by
European Respiratory Journal
Summary
journal-article
CD94+natural killer cells potentiate pulmonary ischaemia–reperfusion injury
Published by
European Respiratory Journal
Summary
journal-article
Reply: The importance of disrupting complement activation in acute lung injury
Published by
Journal of Clinical Investigation
Summary
journal-article
Reply: The importance of disrupting complement activation in acute lung injury
Published by
Journal of Clinical Investigation
Summary
journal-article
Imaging the Granzyme Mediated Host Immune Response to Viral and Bacterial Pathogens In Vivo Using Positron Emission Tomography
Published by
ACS Infectious Diseases
Summary
journal-article
G6b-B antibody-based <em>cis</em>-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics
Summary
preprint
IgG hexamers initiate complement-dependent acute lung injury
Published by
Journal of Clinical Investigation
Summary
journal-article
Loss of neutrophil Shp1 produces hemorrhagic and lethal acute lung injury
Published by
bioRxiv
Summary
working-paper
IgG hexamers initiate acute lung injury
Summary
preprint
Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in the lung and kidney of sickle cell mice
Summary
preprint
Decoding functional hematopoietic progenitor cells in the adult human lung
Summary
preprint
TNIK: A redox sensor in endothelial cell permeability
Published by
Science Advances
Summary
journal-article
Tnik
Published by
Science Advances
Summary
journal-article
Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury
Published by
Journal of Clinical Investigation
Summary
journal-article
Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury
Published by
The Journal of clinical investigation
Summary
journal-article
Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer
Summary
preprint
Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer
Summary
preprint
Optimizing anesthesia and delivery approaches for dosing into lungs of mice
Summary
preprint
Investigating and imaging platelets in inflammation
Published by
International Journal of Biochemistry and Cell Biology
Summary
journal-article
Imaging inflammation
Published by
Progress in Inflammation Research
Summary
book
Optimizing anesthesia and delivery approaches for dosing into lungs of mice
Published by
American Journal of Physiology-Lung Cellular and Molecular Physiology
Summary
journal-article
CCR5 drives NK cell–associated airway damage in pulmonary ischemia-reperfusion injury
Published by
JCI Insight
Summary
journal-article
ADAM8 signaling drives neutrophil migration and ARDS severity
Published by
JCI Insight
Summary
journal-article
Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression
Published by
Journal of Clinical Investigation
Summary
journal-article
Lung megakaryocytes are immune modulatory cells
Published by
Journal of Clinical Investigation
Summary
journal-article
The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection
Published by
Blood Advances
Summary
journal-article
Red Blood Cells Elicit Platelet-Dependent Neutrophil Recruitment Into Lung Airspaces
Published by
Shock
Summary
journal-article
Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3
Published by
American Journal of Respiratory Cell and Molecular Biology
Summary
journal-article
β2M Signals Monocytes Through Non-Canonical TGFβ Receptor Signal Transduction
Published by
Circulation Research
Summary
journal-article
Chewing the fat on TRALI
Published by
Blood
Summary
journal-article
Natural killer cells activated through NKG2D mediate lung ischemia-reperfusion injury
Published by
Journal of Clinical Investigation
Summary
journal-article
Global absence and targeting of protective immune states in severe COVID-19
Published by
Nature
Summary
journal-article
Global absence and targeting of protective immune states in severe COVID-19
Published by
Nature
Summary
journal-article
Global absence and targeting of protective immune states in severe COVID-19
Published by
Nature
Summary
journal-article
Animal models of mechanisms of SARS‐CoV‐2 infection and COVID‐19 pathology
Published by
British Journal of Pharmacology
Summary
journal-article
Global Absence and Targeting of Protective Immune States in Severe COVID-19
Published by
bioRxiv : the preprint server for biology
Summary
working-paper
Global absence and targeting of protective immune states in severe COVID-19.
Published by
bioRxiv
Summary
other
Update on animal models for COVID‐19 research
Published by
British Journal of Pharmacology
Summary
journal-article
Global Absence and Targeting of Protective Immune States in Severe COVID-19.
Summary
preprint
Complement activation on endothelium initiates antibody-mediated acute lung injury
Published by
Journal of Clinical Investigation
Summary
journal-article
Complement activation on endothelium initiates antibody-mediated acute lung injury
Published by
Journal of Clinical Investigation
Summary
journal-article
Radiolabelling and immunohistochemistry reveal platelet recruitment into lungs and platelet migration into airspaces following LPS inhalation in mice
Published by
Journal of Pharmacological and Toxicological Methods
Summary
journal-article
Radiolabelling and immunohistochemistry reveal platelet recruitment into lungs and platelet migration into airspaces following LPS inhalation in mice
Published by
Journal of Pharmacological and Toxicological Methods
Summary
journal-article
Pharmacological strategies for targeting platelet activation in asthma
Published by
Current Opinion in Pharmacology
Summary
journal-article
Mitochondrial DNA Stimulates TLR9-Dependent NET Formation in Primary Graft Dysfunction
Published by
American Journal of Respiratory Cell and Molecular Biology
Summary
journal-article
LPS-Induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-selectin.
Published by
American journal of respiratory cell and molecular biology
Summary
journal-article
LPS-induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-Selectin
Published by
American Journal of Respiratory Cell and Molecular Biology
Summary
journal-article
Sensory nerves mediate spontaneous behaviors in addition to inflammation in a murine model of psoriasis.
Published by
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Summary
journal-article
Platelet Depletion Impairs Host Defense to Pulmonary Infection with Pseudomonas aeruginosa in Mice
Published by
American Journal of Respiratory Cell and Molecular Biology
Summary
journal-article
Platelets Play a Central Role in Sensitization to Allergen.
Published by
American Journal of Respiratory Cell and Molecular Biology
Summary
journal-article
Gustav Born: pioneer in imaging platelet and leukocyte biology
Published by
Platelets
Summary
journal-article
Lipopolysaccharide (LPS) induced pulmonary neutrophil recruitment and platelet activation is mediated via the P2Y 1 and P2Y 14 receptors in mice
Published by
Pulmonary Pharmacology & Therapeutics
Summary
journal-article
The application of local hypobaric pressure - A novel means to enhance macromolecule entry into the skin.
Published by
Journal of Controlled Release
Summary
journal-article
The application of local hypobaric pressure - A novel means to enhance macromolecule entry into the skin.
Summary
journal-article
P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation
Published by
Blood
Summary
journal-article
Exploring dual PDE3/4 inhibition in the treatment of airway diseases
Published by
Drugs of the Future
Summary
journal-article
P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.
Summary
journal-article
P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.
Published by
Blood
Summary
journal-article