Longitudinal paired liver biopsies and transcriptome profiling in alcohol-associated hepatitis reveal dynamic changes in cellular senescence
Published by
Gut
Summary
journal-article
Sofia Ferreira-Gonzalez
Work
University of Edinburgh
|Principal Investigator/Chancellor's fellow
United Kingdom of Great Britain and Northern Ireland
→
University of Edinburgh
|Postdoctoral research associate
United Kingdom of Great Britain and Northern Ireland
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University of Edinburgh
|PhD student
United Kingdom of Great Britain and Northern Ireland
→
Education
University of Edinburgh
United Kingdom of Great Britain and Northern Ireland
→
PhD
University of Navarra
Spain
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MSc Biomedical Research
University of Salamanca
Spain
→
BS Biotechnology (5 years program)
Publications
Host hepatocyte senescence determines the success of hepatocyte transplantation in a mouse model of liver injury
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Journal of Hepatology
Summary
journal-article
Current trends in electrochemical approaches for liver biomarker detection: a mini-review.
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The Analyst
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journal-article
Combining human liver ECM with topographically featured electrospun scaffolds for engineering hepatic microenvironment
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Scientific Reports
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journal-article
Tumor organoids for primary liver cancers: A systematic review of current applications in diagnostics, disease modeling, and drug screening.
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JHEP reports : innovation in hepatology
Summary
journal-article
Closing the computational biology ‘knowledge gap’: Spanish Wikipedia as a case study
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Bioinformatics
Summary
journal-article
Primary cilia as a targetable node between biliary injury, senescence and regeneration in liver transplantation.
Published by
Journal of hepatology
Summary
journal-article
Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage
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Science Translational Medicine
Summary
journal-article
Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage
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Science Translational Medicine
Summary
journal-article
Combination of G-CSF and a TLR4 inhibitor reduce inflammation and promote regeneration in a mouse model of ACLF.
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Journal of hepatology
Summary
journal-article
Combination of G-CSF and a TLR4 inhibitor reduce inflammation and promote regeneration in a mouse model of ACLF
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Journal of Hepatology
Summary
journal-article
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease.
Published by
Cell stem cell
Summary
journal-article
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease
Published by
Cell Stem Cell
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journal-article
Deletion of kif3a in CK19 positive cells leads to primary cilia loss, biliary cell proliferation and cystic liver lesions in TAA-treated mice.
Published by
Biochimica et biophysica acta. Molecular basis of disease
Summary
journal-article
Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation.
Published by
Science signaling
Summary
journal-article
Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation
Published by
Science Signaling
Summary
journal-article
Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure.
Published by
iScience
Summary
journal-article
Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure
Published by
iScience
Summary
journal-article
Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair.
Published by
Science translational medicine
Summary
journal-article
Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair
Published by
Science Translational Medicine
Summary
journal-article
Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.
Published by
Journal of hepatology
Summary
journal-article
Fibroblast growth factor 7 releasing particles enhance islet engraftment and improve metabolic control following islet transplantation in mice with diabetes.
Published by
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Summary
journal-article
Cellular Senescence in Liver Disease and Regeneration.
Published by
Seminars in liver disease
Summary
review
TWEAK/Fn14 signalling promotes cholangiocarcinoma niche formation and progression.
Published by
Journal of hepatology
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journal-article
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.
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Science translational medicine
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journal-article
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration.
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Nature communications
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journal-article
The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury.
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Journal of immunology (Baltimore, Md. : 1950)
Summary
journal-article
Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.
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Nature
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journal-article
Notch3 drives development and progression of cholangiocarcinoma.
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Proceedings of the National Academy of Sciences of the United States of America
Summary
journal-article
Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis.
Published by
Immunity
Summary
journal-article