Taichi Isobe

Work

Kyushu University
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Assistant Professor

Japan

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Kyushu University Hospital

Japan

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Kyushu University
|

Assistant Professor

Japan

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Stanford University

US

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Education

Kyushu University
Japan

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Ph.D.

Oita University
Japan

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M.D.

Publications

Efficacy of pembrolizumab in microsatellite-stable, tumor mutational burden-high metastatic colorectal cancer: genomic signatures and clinical outcomes

Published by

ESMO Open

Summary

journal-article

Development of iPSC-derived T cells targeting EGFR neoantigens in non-small cell lung cancer.

Published by

Molecular therapy. Methods & clinical development

Summary

journal-article

A molecular cell atlas of mouse lemur, an emerging model primate.

Published by

Nature

Summary

journal-article

Mouse lemur cell atlas informs primate genes, physiology and disease.

Published by

Nature

Summary

journal-article

Metastatic urachal carcinoma treated with trifluridine/tipiracil and bevacizumab: a case report

Published by

International Cancer Conference Journal

Summary

journal-article

The E2F4 transcriptional repressor is a key mechanistic regulator of colon cancer resistance to irinotecan(CPT-11)

Summary

preprint

Efficacy of pembrolizumab in microsatellite-stable, tumor mutational burden-high metastatic colorectal cancer: genomic signatures and clinical outcomes

Published by

ESMO Open

Summary

journal-article

Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2–Positive Advanced Gastric Cancer

Published by

JCO Precision Oncology

Summary

journal-article

Spatial dynamics of CD39<sup>+</sup>CD8<sup>+</sup> exhausted T cell reveal tertiary lymphoid structures-mediated response to PD-1 blockade in esophageal cancer

Published by

Nature Communications

Summary

journal-article

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome.

Published by

Nature communications

Summary

journal-article

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome

Published by

Nature Communications

Summary

journal-article

Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2–Positive Advanced Gastric Cancer

Published by

JCO Precision Oncology

Summary

journal-article

Preferential B cell differentiation by combined immune checkpoint blockade for renal cell carcinoma is associated with clinical response and autoimmune reactions

Published by

Cancer Immunology, Immunotherapy

Summary

journal-article

RHAMM marks proliferative subpopulation of human colorectal cancer stem cells

Published by

Cancer Science

Summary

journal-article

Survival outcomes including salvage therapy of adult head and neck para-meningeal rhabdomyosarcoma: a multicenter retrospective study from Japan

Published by

BMC Cancer

Summary

journal-article

Adult head and neck para-meningeal rhabdomyosarcoma: survival outcomes including salvage therapy

Published by

Research Square

Summary

other

RHAMM marks proliferative subpopulation of human colorectal cancer stem cells

Published by

Cancer Science

Summary

journal-article

Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions.

Published by

Cancer letters

Summary

journal-article

Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model

Published by

Gastric Cancer

Summary

journal-article

Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model

Published by

Gastric Cancer

Summary

journal-article

Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203) during terminal differentiation of colon epithelial cells

Published by

Journal of Gastroenterology

Summary

journal-article

Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203) during terminal differentiation of colon epithelial cells

Published by

Journal of Gastroenterology

Summary

journal-article

Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Published by

Nature

Summary

journal-article

Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Published by

Nature

Summary

journal-article

Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets

Published by

Nature Computational Science

Summary

journal-article

Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets

Published by

Nature Computational Science

Summary

journal-article

IMPROVE bleeding score predicts major bleeding in advanced gastrointestinal cancer patients with venous thromboembolism

Published by

Japanese journal of clinical oncology

Summary

journal-article

IMPROVE bleeding score predicts major bleeding in advanced gastrointestinal cancer patients with venous thromboembolism

Published by

Japanese Journal of Clinical Oncology

Summary

journal-article

Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer

Published by

Cancer Science

Summary

journal-article

Inhibition of insulin‐like growth factor‐1 receptor enhances eribulin‐induced DNA damage in colorectal cancer

Published by

Cancer Science

Summary

journal-article

Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions

Published by

Cancer Letters

Summary

journal-article

Mouse lemur transcriptomic atlas informs primate genes, mutations, physiology, and disease

Published by

bioRxiv

Summary

other

Prominent PD-L1-positive M2 macrophage infiltration in gastric cancer with hyper-progression after anti-PD-1 therapy: A case report

Published by

Medicine (United States)

Summary

journal-article

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome

Published by

bioRxiv

Summary

other

Tabula Microcebus: A transcriptomic cell atlas of mouse lemur, an emerging primate model organism

Published by

bioRxiv

Summary

other

Does the use of peripheral immune‐related markers indicate whether to administer pazopanib, trabectedin, or eribulin to advanced soft tissue sarcoma patients?

Published by

Journal of Clinical Medicine

Summary

journal-article

Does the Use of Peripheral Immune-Related Markers Indicate Whether to Administer Pazopanib, Trabectedin, or Eribulin to Advanced Soft Tissue Sarcoma Patients?

Published by

Journal of Clinical Medicine

Summary

journal-article

Predictive impact of C-reactive protein to albumin ratio for recurrent or metastatic head and neck squamous cell carcinoma receiving nivolumab

Published by

Scientific Reports

Summary

journal-article

Predictive impact of C-reactive protein to albumin ratio for recurrent or metastatic head and neck squamous cell carcinoma receiving nivolumab

Published by

Scientific Reports

Summary

journal-article

Prominent PD-L1-positive M2 macrophage infiltration in gastric cancer with hyper-progression after anti-PD-1 therapy A case report

Published by

Medicine

Summary

journal-article

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

Published by

Nature

Summary

journal-article

Eribulin as a first-line treatment for soft tissue sarcoma patients with contraindications for doxorubicin

Published by

Scientific Reports

Summary

journal-article

Eribulin as a first-line treatment for soft tissue sarcoma patients with contraindications for doxorubicin

Published by

Scientific Reports

Summary

journal-article

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

Published by

Nature

Summary

journal-article

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

Published by

Nature

Summary

journal-article

Ageing hallmarks exhibit organ-specific temporal signatures

Published by

Nature

Summary

journal-article

Ageing hallmarks exhibit organ-specific temporal signatures

Published by

Nature

Summary

journal-article

Ageing hallmarks exhibit organ-specific temporal signatures

Published by

Nature

Summary

journal-article

Molecular hallmarks of heterochronic parabiosis at single cell resolution

Published by

bioRxiv

Summary

other

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein–Barr virus-associated gastric cancer

Published by

FEBS Open Bio

Summary

journal-article

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein-Barr virus-associated gastric cancer

Published by

FEBS Open Bio

Summary

journal-article

Organoid culture of human cancer stem cells

Published by

Methods in Molecular Biology

Summary

book-chapter

Methylation of drug resistance‐related genes in chemotherapy‐sensitive Epstein–Barr virus‐associated gastric cancer

Published by

FEBS Open Bio

Summary

journal-article

miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells

Published by

Cancer Research

Summary

journal-article

A single cell transcriptomic atlas characterizes aging tissues in the mouse

Published by

bioRxiv

Summary

other

Organoid Culture of Human Cancer Stem Cells

Published by

Methods in Molecular Biology

Summary

journal-article

miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells

Published by

Cancer Research

Summary

journal-article

MiR-221 targets QKI to enhance the tumorigenic capacity of human colorectal cancer stem cells

Published by

Cancer Research

Summary

journal-article

Single-cell transcriptomics of 20 mouse organs creates a <i>Tabula Muris</i>

Published by

Nature

Summary

journal-article

E-cadherin regulates proliferation of colorectal cancer stem cells through NANOG

Published by

Oncology Reports

Summary

journal-article

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

Published by

Nature

Summary

journal-article

E-cadherin regulates proliferation of colorectal cancer stem cells through NANOG

Published by

Oncology Reports

Summary

journal-article

Organoid Culture of Human Cancer Stem Cells

Published by

Methods in Molecular Biology

Summary

book-chapter

Amrubicin monotherapy for patients with extrapulmonary neuroendocrine carcinoma after platinum-based chemotherapy

Published by

Cancer Chemotherapy and Pharmacology

Summary

journal-article

Amrubicin monotherapy for patients with extrapulmonary neuroendocrine carcinoma after platinum-based chemotherapy

Published by

Cancer Chemotherapy and Pharmacology

Summary

journal-article

miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway

Published by

eLife

Summary

journal-article

Analysis of adverse events of bevacizumab-containing systemic chemotherapy for metastatic colorectal cancer in Japan

Published by

Anticancer Research

Summary

journal-article

Analysis of Adverse Events of Bevacizumab-containing Systemic Chemotherapy for Metastatic Colorectal Cancer in Japan

Published by

Anticancer Research

Summary

journal-article

Analysis of adverse events of bevacizumab-containing systemic chemotherapy for metastatic colorectal cancer in Japan

Published by

Anticancer Research

Summary

journal-article

miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway

Published by

eLife

Summary

journal-article

Systemic chemotherapy for metastatic non-mucinous appendiceal adenocarcinoma: a case report and literature review

Published by

International Cancer Conference Journal

Summary

journal-article

Systemic chemotherapy for metastatic non-mucinous appendiceal adenocarcinoma: a case report and literature review

Published by

International Cancer Conference Journal

Summary

journal-article

Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells

Published by

Experimental Cell Research

Summary

journal-article

Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells

Published by

Experimental Cell Research

Summary

journal-article

Improvement of quality of life and survival using self-expandable metal stent placement for severe malignant stenosis of the gastric body: A case report

Published by

Journal of Medical Case Reports

Summary

journal-article

Improvement of quality of life and survival using self-expandable metal stent placement for severe malignant stenosis of the gastric body: a case report

Published by

Journal of Medical Case Reports

Summary

journal-article

Human STEAP3 maintains tumor growth under hypoferric condition

Published by

Experimental Cell Research

Summary

journal-article

Human STEAP3 maintains tumor growth under hypoferric condition

Published by

Experimental Cell Research

Summary

journal-article

Irinotecan-based combination chemotherapy for metastatic small intestinal adenocarcinoma

Published by

Oncology Letters

Summary

journal-article

Irinotecan-based combination chemotherapy for metastatic small intestinal adenocarcinoma

Published by

Oncology Letters

Summary

journal-article

Schedule-dependent synergistic interaction between gemcitabine and oxaliplatin in human gallbladder adenocarcinoma cell lines

Published by

Anti-Cancer Drugs

Summary

journal-article

Schedule-dependent synergistic interaction between gemcitabine and oxaliplatin in human gallbladder adenocarcinoma cell lines

Published by

Anti-Cancer Drugs

Summary

journal-article

Effective Monotherapy with Amrubicin for a Refractory Extrapulmonary Small-Cell Carcinoma of the Liver

Published by

Case Reports in Medicine

Summary

journal-article

Effective Monotherapy with Amrubicin for a Refractory Extrapulmonary Small-Cell Carcinoma of the Liver

Published by

Case Reports in Medicine

Summary

journal-article

B cell activation regulates exosomal HLA production

Published by

European Journal of Immunology

Summary

journal-article

B cell activation regulates exosomal HLA production

Published by

European Journal of Immunology

Summary

journal-article

Autoimmune thrombocytopenia with clonal expansion of CD8-positive T cells after autologous peripheral blood stem cell transplantation for diffuse large B-cell lymphoma

Published by

Bone Marrow Transplantation

Summary

journal-article

Autoimmune thrombocytopenia with clonal expansion of CD8-positive T cells after autologous peripheral blood stem cell transplantation for diffuse larg B-cell lymphoma [1]

Published by

Bone Marrow Transplantation

Summary

journal-article