Tobias Fuhrer

High-Throughput Metabolomics and Diabetic Kidney Disease Progression: Evidence from the Chronic Renal Insufficiency (CRIC) Study

American Journal of Nephrology

Jan 2022

journal-article

Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

Molecular Systems Biology

Jan 2022

journal-article

Distinct N and C Cross-Feeding Networks in a Synthetic Mouse Gut Consortium

mSystems

Jan 2022

journal-article

Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

Molecular Systems Biology

Jan 2022

journal-article

Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

Molecular Systems Biology

Jan 2022

journal-article

Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism

Nucleic Acids Research

Jan 2022

journal-article

Bifunctional Malic/Malolactic Enzyme Provides a Novel Mechanism for NADPH-Balancing in Bacillus subtilis

mBio

Jan 2021

journal-article

Bifunctional malic/malolactic enzyme provides a novel mechanism for nadph-balancing in bacillus subtilis

mBio

Jan 2021

journal-article

Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ

Cell

Jan 2021

journal-article

Long-term evolution and short-term adaptation of microbiota strains and sub-strains in mice

Cell Host and Microbe

Jan 2021

journal-article

Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

bioRxiv

Jan 2021

other

Distinct N and C cross-feeding networks in a synthetic mouse gut consortium

Jan 2021

preprint

Distinct N and C cross-feeding networks in a synthetic mouse gut consortium

bioRxiv

Jan 2021

other

Distinct N and C cross-feeding networks in a synthetic mouse gut consortium

Jan 2021

preprint

Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress

The ISME Journal

Jan 2021

journal-article

Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress

ISME Journal

Jan 2021

journal-article

Co‐catabolism of arginine and succinate drives symbiotic nitrogen fixation

Molecular Systems Biology

Jan 2020

journal-article

Co-catabolism of arginine and succinate drives symbiotic nitrogen fixation

Molecular Systems Biology

Jan 2020

journal-article

Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study

American Journal of Kidney Diseases

Jan 2020

journal-article

Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study

American Journal of Kidney Diseases

Jan 2020

journal-article

Reserve Flux Capacity in the Pentose Phosphate Pathway by NADPH Binding Is Conserved across Kingdoms

iScience

Jan 2019

journal-article

Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice

Nature Microbiology

Jan 2019

journal-article

Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice

Nature Microbiology

Jan 2019

journal-article

Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB

Proceedings of the National Academy of Sciences

Jan 2019

journal-article

Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB

Proceedings of the National Academy of Sciences

Jan 2019

journal-article

Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB

Proceedings of the National Academy of Sciences of the United States of America

Jan 2019

journal-article

Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection

Nature Communications

Jan 2019

journal-article

Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection

Nature Communications

Jan 2019

journal-article

Reserve Flux Capacity in the Pentose Phosphate Pathway by NADPH Binding Is Conserved across Kingdoms

iScience

Jan 2019

journal-article

2 H/ 1 H variation in microbial lipids is controlled by NADPH metabolism

Proceedings of the National Academy of Sciences

Jan 2019

journal-article

²H/¹H variation in microbial lipids is controlled by NADPH metabolism

Proceedings of the National Academy of Sciences of the United States of America

Jan 2019

journal-article

(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch

Molecular Cell

Jan 2019

journal-article

(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch

Molecular Cell

Jan 2019

journal-article

Purity by design: Reducing impurities in bioproduction by stimulus-controlled global translational downregulation of non-product proteins

Metabolic Engineering

Jan 2019

journal-article

Purity by design: Reducing impurities in bioproduction by stimulus-controlled global translational downregulation of non-product proteins

Metabolic Engineering

Jan 2019

journal-article

Metabolic Remodeling during Liver Regeneration

Developmental Cell

Jan 2018

journal-article

Metabolic Remodeling during Liver Regeneration

Developmental Cell

Jan 2018

journal-article

Synthesis and degradation of FtsZ quantitatively predict the first cell division in starved bacteria

Molecular Systems Biology

Jan 2018

journal-article

Synthesis and degradation of FtsZ quantitatively predict the first cell division in starved bacteria

Molecular Systems Biology

Jan 2018

journal-article

Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response

Immunity

Jan 2018

journal-article

A Map of Protein-Metabolite Interactions Reveals Principles of Chemical Communication

Cell

Jan 2018

journal-article

Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response

Immunity

Jan 2018

journal-article

The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation

Nature Communications

Jan 2018

journal-article

The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation

Nature Communications

Jan 2018

journal-article

Reserve Flux Capacity in the Pentose Phosphate Pathway Enables Escherichia coli's Rapid Response to Oxidative Stress

Cell Systems

Jan 2018

journal-article

Reserve Flux Capacity in the Pentose Phosphate Pathway Enables Escherichia coli's Rapid Response to Oxidative Stress

Cell Systems

Jan 2018

journal-article

A Map of Protein-Metabolite Interactions Reveals Principles of Chemical Communication

Cell

Jan 2018

journal-article

Maternal microbiota and antibodies as advocates of neonatal health

Gut Microbes

Jan 2017

journal-article

Antibodies set boundaries limiting microbial metabolite penetration and the resultant mammalian host response

bioRxiv

Jan 2017

other

Maternal microbiota and antibodies as advocates of neonatal health.

Jan 2017

journal-article

Maternal microbiota and antibodies as advocates of neonatal health

Gut Microbes

Jan 2017

journal-article

Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli

Nature Methods

Jan 2017

journal-article

Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli

Nature Methods

Jan 2017

journal-article

Genomewide landscape of gene–metabolome associations in Escherichia coli

Molecular Systems Biology

Jan 2017

journal-article

Genomewide landscape of gene–metabolome associations in Escherichia coli

Molecular Systems Biology

Jan 2017

journal-article

Glycolysis without pyruvate kinase in Clostridium thermocellum.

Jan 2017

journal-article

Glycolysis without pyruvate kinase in Clostridium thermocellum

Metabolic Engineering

Jan 2017

journal-article

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

Jan 2016

journal-article

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

Cell

Jan 2016

journal-article

The maternal microbiota drives early postnatal innate immune development.

Jan 2016

journal-article

The maternal microbiota drives early postnatal innate immune development

Science

Jan 2016

journal-article

Real-time metabolome profiling of the metabolic switch between starvation and growth.

Jan 2015

journal-article

Real-time metabolome profiling of the metabolic switch between starvation and growth

Nature Methods

Jan 2015

journal-article

Pseudomonas putida KT2440 Strain Metabolizes Glucose through a Cycle Formed by Enzymes of the Entner-Doudoroff, Embden-Meyerhof-Parnas, and Pentose Phosphate Pathways.

Jan 2015

journal-article

Pseudomonas putida KT2440 strain metabolizes glucose through a cycle formed by enzymes of the Entner-Doudoroff, embden-meyerhof-parnas, and pentose phosphate pathways

Journal of Biological Chemistry

Jan 2015

journal-article

The outer mucus layer hosts a distinct intestinal microbial niche.

Jan 2015

journal-article

The outer mucus layer hosts a distinct intestinal microbial niche

Nature Communications

Jan 2015

journal-article

High-throughput discovery metabolomics

Current Opinion in Biotechnology

Jan 2015

journal-article

High-throughput discovery metabolomics

Current Opinion in Biotechnology

Jan 2015

journal-article

Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21

Proceedings of the National Academy of Sciences of the United States of America

Jan 2014

journal-article

Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21

Proceedings of the National Academy of Sciences of the United States of America

Jan 2014

journal-article

Identification of transcriptional and metabolic programs related to mammalian cell size

Curr Biol

Jan 2014

journal-article

Identification of transcriptional and metabolic programs related to mammalian cell size

Current Biology

Jan 2014

journal-article

Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli.

Jan 2014

journal-article

Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli

Molecular Systems Biology

Jan 2014

journal-article

Cra regulates the cross-talk between the two branches of the phosphoenolpyruvate: phosphotransferase system of Pseudomonas putida

Environmental Microbiology

Jan 2013

journal-article

Cra regulates the cross-talk between the two branches of the phosphoenolpyruvate: Phosphotransferase system of Pseudomonas putida

Environmental Microbiology

Jan 2013

journal-article

Acetate scavenging activity in Escherichia coli: interplay of acetyl-CoA synthetase and the PEP-glyoxylate cycle in chemostat cultures

Applied Microbiology and Biotechnology

Jan 2012

journal-article

Acetate scavenging activity in Escherichia coli: Interplay of acetyl-CoA synthetase and the PEP-glyoxylate cycle in chemostat cultures

Applied Microbiology and Biotechnology

Jan 2012

journal-article

Global probabilistic annotation of metabolic networks enables enzyme discovery

Nat Chem Biol

Jan 2012

journal-article

Global probabilistic annotation of metabolic networks enables enzyme discovery

Nature Chemical Biology

Jan 2012

journal-article

High-Throughput, Accurate Mass Metabolome Profiling of Cellular Extracts by Flow Injection - Time-of-Flight Mass Spectrometry

Analytical Chemistry

Jan 2011

journal-article

High-throughput, accurate mass metabolome profiling of cellular extracts by flow injection-time-of-flight mass spectrometry

Analytical Chemistry

Jan 2011

journal-article

Metabolism of Pentose Sugars in the Hyperthermophilic Archaea Sulfolobus solfataricus and Sulfolobus acidocaldarius

Journal of Biological Chemistry

Jan 2010

journal-article

Metabolism of pentose sugars in the hyperthermophilic archaea Sulfolobus solfataricus and Sulfolobus acidocaldarius

Journal of Biological Chemistry

Jan 2010

journal-article

The Nonphosphorylative Entner-Doudoroff Pathway in the Thermoacidophilic Euryarchaeon Picrophilus torridus Involves a Novel 2-Keto-3-Deoxygluconate-Specific Aldolase

Journal of Bacteriology

Jan 2010

journal-article

The nonphosphorylative entner-doudoroff pathway in the thermoacidophilic euryarchaeon Picrophilus torridus involves a novel 2-Keto-3-deoxygluconate- specific aldolase

Journal of Bacteriology

Jan 2010

journal-article

D-Xylose Degradation Pathway in the Halophilic Archaeon Haloferax volcanii

Journal of Biological Chemistry

Jan 2009

journal-article

D-xylose degradation pathway in the halophilic archaeon Haloferax volcanii

Journal of Biological Chemistry

Jan 2009

journal-article

Different Biochemical Mechanisms Ensure Network-Wide Balancing of Reducing Equivalents in Microbial Metabolism

Journal of Bacteriology

Jan 2009

journal-article

Different biochemical mechanisms ensure network-wide balancing of reducing equivalents in microbial metabolism

Journal of Bacteriology

Jan 2009

journal-article

Computational prediction and experimental verification of the gene encoding the NAD(+)/NADP(+)-dependent succinate semialdehyde dehydrogenase in Escherichia coli

Journal of Bacteriology

Jan 2007

journal-article

Computational prediction and experimental verification of the gene encoding the NAD⁺/NADP⁺-dependent succinate semialdehyde dehydrogenase in Escherichia coli

Journal of Bacteriology

Jan 2007

journal-article

Convergent peripheral pathways catalyze initial glucose catabolism in Pseudomonas putida: Genomic and flux analysis

Journal of Bacteriology

Jan 2007

journal-article

Convergent peripheral pathways catalyze initial glucose catabolism in Pseudomonas putida: Genomic and flux analysis

Journal of Bacteriology

Jan 2007

journal-article

Determination of metabolic flux ratios from C-13-experiments and gas chromatography-mass spectrometry data - Protocol and principles

Methods in Molecular Biology

Jan 2007

book-chapter

Determination of metabolic flux ratios from 13C-experiments and gas chromatography-mass spectrometry data: protocol and principles.

Methods in molecular biology (Clifton, N.J.)

Jan 2007

journal-article

Experimental identification and quantification of glucose metabolism in seven bacterial species

Journal of Bacteriology

Jan 2005

journal-article

Experimental identification and quantification of glucose metabolism in seven bacterial species

Journal of Bacteriology

Jan 2005

journal-article

Multiple and interconnected pathways for L-lysine catabolism in Pseudomonas putida KT2440

Journal of Bacteriology

Jan 2005

journal-article

Multiple and interconnected pathways for l-lysine catabolism in Pseudomonas putida KT2440

Journal of Bacteriology

Jan 2005

journal-article

Tobias Fuhrer

Education

ETH Zurich

Publications

High-Throughput Metabolomics and Diabetic Kidney Disease Progression: Evidence from the Chronic Renal Insufficiency (CRIC) Study

Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

Distinct N and C Cross-Feeding Networks in a Synthetic Mouse Gut Consortium

Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism

Bifunctional Malic/Malolactic Enzyme Provides a Novel Mechanism for NADPH-Balancing in Bacillus subtilis

Bifunctional malic/malolactic enzyme provides a novel mechanism for nadph-balancing in bacillus subtilis

Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ

Long-term evolution and short-term adaptation of microbiota strains and sub-strains in mice

Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

Distinct N and C cross-feeding networks in a synthetic mouse gut consortium

Distinct N and C cross-feeding networks in a synthetic mouse gut consortium

Distinct N and C cross-feeding networks in a synthetic mouse gut consortium

Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress

Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress

Co‐catabolism of arginine and succinate drives symbiotic nitrogen fixation

Co-catabolism of arginine and succinate drives symbiotic nitrogen fixation

Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study

Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study

Reserve Flux Capacity in the Pentose Phosphate Pathway by NADPH Binding Is Conserved across Kingdoms

Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice

Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice

Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB

Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB

Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB

Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection

Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection

Reserve Flux Capacity in the Pentose Phosphate Pathway by NADPH Binding Is Conserved across Kingdoms

2 H/ 1 H variation in microbial lipids is controlled by NADPH metabolism

2H/1H variation in microbial lipids is controlled by NADPH metabolism

(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch

(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch

Purity by design: Reducing impurities in bioproduction by stimulus-controlled global translational downregulation of non-product proteins

Purity by design: Reducing impurities in bioproduction by stimulus-controlled global translational downregulation of non-product proteins

Metabolic Remodeling during Liver Regeneration

Metabolic Remodeling during Liver Regeneration

Synthesis and degradation of FtsZ quantitatively predict the first cell division in starved bacteria

Synthesis and degradation of FtsZ quantitatively predict the first cell division in starved bacteria

Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response

A Map of Protein-Metabolite Interactions Reveals Principles of Chemical Communication

Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response

The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation

The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation

Reserve Flux Capacity in the Pentose Phosphate Pathway Enables Escherichia coli's Rapid Response to Oxidative Stress

Reserve Flux Capacity in the Pentose Phosphate Pathway Enables Escherichia coli's Rapid Response to Oxidative Stress

A Map of Protein-Metabolite Interactions Reveals Principles of Chemical Communication

Maternal microbiota and antibodies as advocates of neonatal health

Antibodies set boundaries limiting microbial metabolite penetration and the resultant mammalian host response

Maternal microbiota and antibodies as advocates of neonatal health.

Maternal microbiota and antibodies as advocates of neonatal health

Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli

Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli

Genomewide landscape of gene–metabolome associations in Escherichia coli

Genomewide landscape of gene–metabolome associations in Escherichia coli

Glycolysis without pyruvate kinase in Clostridium thermocellum.

Glycolysis without pyruvate kinase in Clostridium thermocellum

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

The maternal microbiota drives early postnatal innate immune development.

The maternal microbiota drives early postnatal innate immune development

Real-time metabolome profiling of the metabolic switch between starvation and growth.

Real-time metabolome profiling of the metabolic switch between starvation and growth

Pseudomonas putida KT2440 Strain Metabolizes Glucose through a Cycle Formed by Enzymes of the Entner-Doudoroff, Embden-Meyerhof-Parnas, and Pentose Phosphate Pathways.

Pseudomonas putida KT2440 strain metabolizes glucose through a cycle formed by enzymes of the Entner-Doudoroff, embden-meyerhof-parnas, and pentose phosphate pathways

The outer mucus layer hosts a distinct intestinal microbial niche.

The outer mucus layer hosts a distinct intestinal microbial niche

High-throughput discovery metabolomics

High-throughput discovery metabolomics

Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21

Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21

Identification of transcriptional and metabolic programs related to mammalian cell size

Identification of transcriptional and metabolic programs related to mammalian cell size

Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli.

Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli

Cra regulates the cross-talk between the two branches of the phosphoenolpyruvate: phosphotransferase system of Pseudomonas putida

²H/¹H variation in microbial lipids is controlled by NADPH metabolism

Computational prediction and experimental verification of the gene encoding the NAD⁺/NADP⁺-dependent succinate semialdehyde dehydrogenase in Escherichia coli