Arianna Baggiolini

About

Dr. Arianna Baggiolini is a Group Leader at the Institute of Oncology Research (www.ior.usi.ch) of BIOS+ (www.biosplus.ch) in Switzerland. Arianna is a stem cell and cancer biologist. She is interested in defining how developmental programs are reactivated during the acquisition of a malignant state and how they regulate tumor formation and progression. Her lab (www.baggiolinilab.com) combines in vivo models and human pluripotent stem cell (hPSC)-based technologies to address how malignancy is regulated cell-intrinsically and depending on the microenvironment. Arianna has received a number of awards including the Tri-Institutional Breakout Price, the SNSF Starting grant, the Christopher J. Marshall Award from the Society for Melanoma Research (SMR) and was elected Leading Edge Fellow 2021. In 2024, Arianna was awarded the prestigious Hofschneider professorship.

Work

Institute of Oncology Research
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Group Leader and Assistant Professor at the Università della Svizzera italiana (USI)

Switzerland

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Sloan Kettering Institute
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Research Fellow

US

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University of Zurich
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Postdoc

Switzerland

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Education

University of Zurich
Switzerland

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PhD in Neuroscience (ETHZ and UZH)

ETH
Switzerland

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Master of Science ETH in Biology

ETH
Switzerland

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Bachelor of Science ETH in Biology

Publications

Oncogenic competence: balancing mutations, cellular state, and microenvironment

Published by

Trends in Cancer

Summary

journal-article

Author Correction: Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons

Published by

Nature Biotechnology

Summary

journal-article

Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons

Published by

Nature Biotechnology

Summary

journal-article

Protocol for generating human cortical organoids enriched in outer radial glia by guided differentiation

Published by

STAR Protocols

Summary

journal-article

Harmony in chaos: understanding cancer through the lenses of developmental biology

Published by

Molecular Oncology

Summary

journal-article

An epigenetic barrier sets the timing of human neuronal maturation

Published by

Nature

Summary

journal-article

DNA damage remodels the MITF interactome to increase melanoma genomic instability

Published by

Genes & Development

Summary

journal-article

Lipid droplets are a metabolic vulnerability in melanoma

Published by

Nature Communications

Summary

journal-article

DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition

Summary

preprint

hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease

Published by

Cell Stem Cell

Summary

journal-article

Generation of human cerebral organoids with a structured outer subventricular zone

Summary

preprint

Epigenetic reprogramming of melanoma cell state through fatty acid β-oxidation and Toll-like receptor 4 signaling

Summary

preprint

An epigenetic barrier sets the timing of human neuronal maturation

Summary

preprint

Combined small molecule treatment accelerates timing of maturation in human pluripotent stem cell-derived neurons

Summary

preprint

Combined small molecule treatment accelerates timing of maturation in human pluripotent stem cell-derived neurons

Summary

preprint

Lipid droplets are a metabolic vulnerability in melanoma

Summary

preprint

Anatomic position determines oncogenic specificity in melanoma

Published by

Nature

Summary

journal-article

Developmental chromatin programs determine oncogenic competence in melanoma

Published by

Science

Summary

journal-article

Developmental chromatin programs determine oncogenic competence in melanoma

Published by

Science

Summary

journal-article

Developmental chromatin programs determine oncogenic competence in melanoma

Published by

Science

Summary

journal-article

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4

Published by

Nature Communications

Summary

journal-article

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4

Published by

Nature Communications

Summary

journal-article

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4

Published by

Nature Communications

Summary

journal-article

Anatomic position determines oncogenic specificity in melanoma

Summary

preprint

Developmental chromatin programs determine oncogenic competence in melanoma

Summary

preprint

Developmental chromatin programs determine oncogenic competence in melanoma

Summary

preprint

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation

Published by

Cell Stem Cell

Summary

journal-article

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.

Published by

Cell stem cell

Summary

journal-article

Premigratory and migratory neural crest cells are multipotent in vivo.

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journal-article

Mature oligodendrocytes actively increase in vivo cytoskeletal plasticity following CNS damage.

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HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia.

Summary

journal-article

Ezh2 is required for neural crest-derived cartilage and bone formation.

Summary

journal-article

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells.

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journal-article