Artur Wnorowski

Work

Medical University of Lublin
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Assistant Professor

Poland

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APA Laboratory
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CEO

Poland

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Education

Medical University of Lublin
Poland

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PhD

Warsaw University of Life Sciences
Poland

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MSc

Publications

Exploring the impact of MDMA and oxytocin ligands on anxiety and social responses: A comprehensive behavioural and molecular study in the zebrafish model

Published by

Journal of Psychopharmacology

Summary

journal-article

Structure prediction analysis of human core TIM23 complex reveals conservation of the protein translocation mechanism

Published by

FEBS Open Bio

Summary

journal-article

Low-Basicity 5-HT6 Receptor Ligands from the Group of Cyclic Arylguanidine Derivatives and Their Antiproliferative Activity Evaluation

Published by

International Journal of Molecular Sciences

Summary

journal-article

Low-Basicity 5-HT<sub>6</sub> Receptor Ligands from the Group of Cyclic Arylguanidine Derivatives and Their Antiproliferative Activity Evaluation

Published by

International Journal of Molecular Sciences

Summary

journal-article

Menopausal Status Contributes to Overall Survival in Endometrial Cancer Patients

Published by

Cancers

Summary

journal-article

Use of dimethyl sulfoxide in prevention and treatment of SARS-CoV-2 and pharmaceutical composition for use in prevention and treatment of upper respiratory tract infection caused by SARS-CoV 2 virus

Summary

patent

Menopausal Status Contributes to Overall Survival in Endometrial Cancer Patients

Published by

Cancers

Summary

journal-article

Zirconium-Based Metal–Organic Frameworks as Acriflavine Cargos in the Battle against Coronaviruses─A Theoretical and Experimental Approach

Published by

ACS Applied Materials &amp; Interfaces

Summary

journal-article

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist

Published by

Scientific Reports

Summary

journal-article

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist

Published by

Scientific Reports

Summary

journal-article

Evidence against involvement of kynurenate branch of kynurenine pathway in pathophysiology of Fuchs’ dystrophy and keratoconus

Published by

Experimental Eye Research

Summary

journal-article

Evidence against involvement of kynurenate branch of kynurenine pathway in pathophysiology of Fuchs’ dystrophy and keratoconus

Published by

Experimental Eye Research

Summary

journal-article

Pharmacological assessment of zebrafish-based cardiotoxicity models

Published by

Biomedicine & Pharmacotherapy

Summary

journal-article

Evaluation of β-adrenergic ligands for development of pharmacological heart failure and transparency models in zebrafish

Published by

Toxicology and Applied Pharmacology

Summary

journal-article

Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation

Published by

Molecules

Summary

journal-article

Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca<sup>2+</sup> Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation

Published by

Molecules

Summary

journal-article

Carlina oxide inhibits the interaction of SARS-CoV-2 S glycoprotein with angiotensin-converting enzyme 2

Published by

Industrial Crops and Products

Summary

journal-article

Eco-friendly methods of synthesis and preliminary biological evaluation of sulfonamide derivatives of cyclic arylguanidines

Published by

Ultrasonics Sonochemistry

Summary

journal-article

Application of carlina oxide for prevention of SARS-CoV-2 virus infection and treatment of COVID-19 disease

Summary

patent

Method of depigmenting a fish research model, especially of the Danio rerio species with the use of isoetarin, and the use of isoetarin for depigmentation of a fish research model, especially of the Danio rerio species

Summary

patent

Application of the SMALP technology to the isolation of GPCRs from low-yielding cell lines

Summary

preprint

Alterations in Kynurenine and NAD<sup>+</sup> Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets

Published by

International Journal of Molecular Sciences

Summary

journal-article

Alterations in Kynurenine and NAD+ Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets

Published by

International Journal of Molecular Sciences

Summary

journal-article

Alterations in kynurenine and NAD<sup>+</sup> salvage pathways during the successful treatment of inflammatory bowel disease suggest HCAR3 and NNMT as potential drug targets

Published by

International Journal of Molecular Sciences

Summary

journal-article

Gene Expression Data Mining Reveals the Involvement of GPR55 and Its Endogenous Ligands in Immune Response, Cancer, and Differentiation

Published by

International Journal of Molecular Sciences

Summary

journal-article

Gene Expression Data Mining Reveals the Involvement of GPR55 and Its Endogenous Ligands in Immune Response, Cancer, and Differentiation

Published by

International Journal of Molecular Sciences

Summary

journal-article

Gene expression data mining reveals the involvement of GPR55 and its endogenous ligands in immune response, cancer, and differentiation

Published by

International Journal of Molecular Sciences

Summary

journal-article

Method of depigmenting a fish research model, especially of the Danio rerio species with the use of isoetarin, and the use of isoetarin for depigmentation of a fish research model, especially of the Danio rerio species

Summary

patent

Synthesis of New Hantzsch Adducts Showing Ca 2+ Channel Blockade capacity, Cholinesterase Inhibition and Antioxidant Power

Published by

Future Medicinal Chemistry

Summary

journal-article

Kynurenine emerges from the shadows – Current knowledge on its fate and function

Published by

Pharmacology & Therapeutics

Summary

journal-article

Kynurenine emerges from the shadows - current knowledge on its fate and function

Published by

Pharmacology & Therapeutics

Summary

journal-article

Application of the SMALP technology to the isolation of GPCRs from low-yielding cell lines

Published by

Biochimica et Biophysica Acta-Biomembranes

Summary

journal-article

Application of the SMALP technology to the isolation of GPCRs from low-yielding cell lines

Published by

Biochimica et Biophysica Acta-Biomembranes

Summary

journal-article

Synthesis of new Hantzsch adducts showing Ca<sup>2+</sup> channel blockade capacity, cholinesterase inhibition and antioxidant power

Published by

Future Medicinal Chemistry

Summary

journal-article

Type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors induce antidepressant-like activity in mice by a mechanism involving receptor potentiation but not neurotransmitter reuptake inhibition. Correlation with mTOR intracellular pathway activation

Published by

European Neuropsychopharmacology

Summary

journal-article

Design, synthesis and biological evaluation of new antioxidant and neuroprotective multitarget directed ligands able to block calcium channels

Published by

Molecules

Summary

journal-article

Diazepam and SL-327 synergistically attenuate anxiety-like behaviours in mice – Possible hippocampal MAPKs specificity

Published by

Neuropharmacology

Summary

journal-article

Diazepam and SL-327 synergistically attenuate anxiety-like behaviours in mice - Possible hippocampal MAPKs specificity

Published by

Neuropharmacology

Summary

journal-article

Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives

Published by

International Journal of Molecular Sciences

Summary

journal-article

Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives

Published by

International Journal of Molecular Sciences

Summary

journal-article

Synthesis of Hantzsch adducts as cholinesterases and calcium flux inhibitors, antioxidants and neuroprotectives

Published by

International Journal of Molecular Sciences

Summary

journal-article

AhR and IDO1 in pathogenesis of Covid-19 and the “Systemic AhR Activation Syndrome:” a translational review and therapeutic perspectives

Published by

Restorative Neurology and Neuroscience

Summary

journal-article

AhR and IDO1 in pathogenesis of Covid-19 and the “Systemic AhR Activation Syndrome”: Translational review and therapeutic perspectives

Published by

Restorative Neurology and Neuroscience

Summary

journal-article

Kynurenic acid and cancer: facts and controversies

Published by

Cellular and Molecular Life Sciences

Summary

journal-article

Toxicity of Carlina Oxide—A Natural Polyacetylene from the Carlina acaulis Roots—In Vitro and in Vivo Study

Published by

Toxins

Summary

journal-article

Toxicity of Carlina Oxide—A Natural Polyacetylene from the <i>Carlina acaulis</i> Roots—In Vitro and In Vivo Study

Published by

Toxins

Summary

journal-article

Kynurenic acid and cancer: facts and controversies

Published by

Cellular and Molecular Life Sciences

Summary

journal-article

Toxicity of carlina oxide - a natural polyacetylene from the Carlina acaulis roots - in vitro and in vivo study

Published by

Toxins

Summary

journal-article

Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels

Published by

Molecules

Summary

journal-article

Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels

Published by

Molecules

Summary

journal-article

Angiotensin II type 1 receptor blockers decrease kynurenic acid production in rat kidney in vitro

Published by

Naunyn-Schmiedebergs Archives of Pharmacology

Summary

journal-article

Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer’s disease therapy

Published by

Bioorganic Chemistry

Summary

journal-article

Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer’s disease therapy

Published by

Bioorganic Chemistry

Summary

journal-article

Novel functionalized β-nitrostyrenes: Promising candidates for new antibacterial drugs

Published by

Saudi Pharmaceutical Journal

Summary

journal-article

Novel functionalized β-nitrostyrenes: Promising candidates for new antibacterial drugs

Published by

Saudi Pharmaceutical Journal

Summary

journal-article

The presence and distribution of G protein-coupled receptor 35 (GPR35) in the human cornea – Evidences from in silico gene expression analysis and immunodetection

Published by

Experimental Eye Research

Summary

journal-article

The presence and distribution of G protein-coupled receptor 35 (GPR35) in the human cornea - evidences from <i>in silico</i> gene expression analysis and immunodetection

Published by

Experimental Eye Research

Summary

journal-article

Influence of cyclooxygenase-2 inhibitors on kynurenic acid production in rat brain in vitro

Published by

Neurotoxicity Research

Summary

journal-article

Effect of Kynurenic Acid on Pupae Viability of Drosophila melanogaster cinnabar and cardinal Eye Color Mutants with Altered Tryptophan-Kynurenine Metabolism

Published by

Neurotoxicity Research

Summary

journal-article

Effect of kynurenic acid on pupae viability of drosophila melanogaster cinnabar and cardinal eye color mutants with altered tryptophan-kynurenine metabolism

Published by

Neurotoxicity Research

Summary

journal-article

Identification of new mechanism of action of angiotensin II type 1 receptor blockers, inhibitors of cyclooxygenase-2 and fibrates - a novel modulators of glutamatergic neurotransmission?

Published by

Folia Neuropathologica

Summary

journal-article

Influence of Cyclooxygenase-2 Inhibitors on Kynurenic Acid Production in Rat Brain in Vitro

Published by

Neurotoxicity Research

Summary

journal-article

Chronic inflammatory microenvironment in epidermodysplasia verruciformis skin lesions: role of the synergism between HPV8 E2 and C/EBPβ to induce pro-inflammatory S100A8/A9 proteins

Published by

Frontiers in Microbiology

Summary

journal-article

Chronic inflammatory microenvironment in epidermodysplasia verruciformis skin lesions: Role of the synergism between HPV8 E2 and C/EBPβ to induce pro-inflammatory S100A8/A9 proteins

Published by

Frontiers in Microbiology

Summary

journal-article

Kynurenic Acid Protects against Thioacetamide-Induced Liver Injury in Rats

Published by

Analytical cellular pathology (Amsterdam)

Summary

journal-article

Kynurenic Acid Protects against Thioacetamide-Induced Liver Injury in Rats

Published by

Analytical Cellular Pathology

Summary

journal-article

Kynurenic acid protects against thioacetamide-induced liver injury in rats

Published by

Analytical Cellular Pathology

Summary

journal-article

Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease

Published by

European Journal of Medicinal Chemistry

Summary

journal-article

Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease

Published by

European Journal of Medicinal Chemistry

Summary

journal-article

The influence of candesartan on kynurenic acid production in rat kidney in vitro

Published by

Nephrology Dialysis Transplantation

Summary

journal-article

Acute MDMA and nicotine co-administration: Behavioral effects and oxidative stress processes in mice

Published by

Frontiers in Behavioral Neuroscience

Summary

journal-article

Acute MDMA and nicotine co-administration: behavioral effects and oxidative stress processes in mice

Published by

Frontiers in Behavioral Neuroscience

Summary

journal-article

Ligand-induced action of the W286<sup>6.48</sup> rotamer toggle switch in β<sub>2</sub>-adrenergic receptor

Published by

Physical Chemistry Chemical Physics

Summary

journal-article

Angiotensin II type 1 receptor blockers decrease kynurenic acid production in rat kidney in vitro

Published by

Naunyn-Schmiedeberg's Archives of Pharmacology

Summary

journal-article

Chronic Inflammatory Microenvironment in Epidermodysplasia Verruciformis Skin Lesions: Role of the Synergism Between HPV8 E2 and C/EBPβ to Induce Pro-Inflammatory S100A8/A9 Proteins

Published by

Frontiers in Microbiology

Summary

journal-article

The presence of kynurenine aminotransferases in the human cornea: evidence from bioinformatics analysis of gene expression and immunohistochemical staining

Published by

Molecular Vision

Summary

journal-article

To block it, or not to block it?

Published by

Journal of Cancer Research and Clinical Oncology

Summary

journal-article

To block it, or not to block it?

Published by

Journal of Cancer Research and Clinical Oncology

Summary

journal-article

To block it, or not to block it?

Published by

Journal of Cancer Research and Clinical Oncology

Summary

journal-article

GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts

Published by

International Journal of Cancer

Summary

journal-article

Ligand-induced action of the W2866.48 rotamer toggle switch in the β2-adrenergic receptor.

Published by

Physical chemistry chemical physics : PCCP

Summary

journal-article

Ligand-induced action of the W286<sup>6.48</sup>rotamer toggle switch in the β<inf>2</inf>-adrenergic receptor

Published by

Physical Chemistry Chemical Physics

Summary

journal-article

Concurrent activation of β 2 -adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells

Published by

Cellular Signalling

Summary

journal-article

Concurrent activation of β<inf>2</inf>-adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells

Published by

Cellular Signalling

Summary

journal-article

Concurrent activation of β<sub>2</sub>-adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells

Published by

Cellular Signalling

Summary

journal-article

(<i>R,R′</i>)-4′-metoksy-1-naftylfenoterol jako potencjalny wielocelowy lek przeciwnowotworowy

Published by

Postępy Polskiej Medycyny i Farmacji

Summary

journal-article

Angiotensin II Type 1 Receptor Blockers Inhibit KAT II Activity in the Brain—Its Possible Clinical Applications

Published by

Neurotoxicity Research

Summary

journal-article

Angiotensin II type 1 receptor blockers inhibit KAT II activity in the brain - its possible clinical applications

Published by

Neurotoxicity Research

Summary

journal-article

GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts

Published by

International Journal of Cancer

Summary

journal-article

In vitro antiproliferative activity of extracts of Carlina acaulis subsp. caulescens and Carlina acanthifolia subsp. utzka

Published by

Frontiers in Pharmacology

Summary

journal-article

In vitro antiproliferative activity of extracts of <i>Carlina acaulis</i> subsp. <i>caulescens</i> and <i>Carlina acanthifolia</i> subsp. <i>utzka</i>

Published by

Frontiers in Pharmacology

Summary

journal-article

Kynurenic Acid and Neuroprotective Activity of the Ketogenic Diet in the Eye

Published by

Current medicinal chemistry

Summary

journal-article

Kynurenic acid and neuroprotective activity of the ketogenic diet in the eye

Published by

Current Medicinal Chemistry

Summary

journal-article

Metabolic activity of tree saps of different origin towards cultured human cells in the light of grade correspondence analysis and multiple regression modeling

Published by

Acta Societatis Botanicorum Poloniae

Summary

journal-article

Metabolic activity of tree saps of different origin towards cultured human cells in the light of grade correspondence analysis and multiple regression modeling

Published by

Acta Societatis Botanicorum Poloniae

Summary

journal-article

The presence of kynurenine aminotransferases in the human cornea: Evidence from bioinformatics analysis of gene expression and immunohistochemical staining

Published by

Molecular Vision

Summary

journal-article

Novel synthesis scheme and in vitro antimicrobial evaluation of a panel of (E)-2-aryl-1-cyano-1-nitroethenes.

Summary

journal-article

Novel synthesis scheme and in vitro antimicrobial evaluation of a panel of (E)-2-aryl-1-cyano-1-nitroethenes

Published by

Journal of Enzyme Inhibition and Medicinal Chemistry

Summary

journal-article

Novel synthesis scheme and in vitro antimicrobial evaluation of a panel of (E)-2-aryl-1-cyano-1-nitroethenes

Published by

Journal of Enzyme Inhibition and Medicinal Chemistry

Summary

journal-article

Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet.

Summary

journal-article

Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet

Published by

Aging

Summary

journal-article

Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet

Published by

Aging-US

Summary

journal-article

The positive allosteric modulator of α7 nicotinic acetylcholine receptors, 3-furan-2-yl-N-p-tolyl-acrylamide, enhances memory processes and stimulates ERK1/2 phosphorylation in mice.

Summary

journal-article

The positive allosteric modulator of α7 nicotinic acetylcholine receptors, 3-furan-2-yl-N-p-tolyl-acrylamide, enhances memory processes and stimulates ERK1/2 phosphorylation in mice

Published by

Behavioural Brain Research

Summary

journal-article

The positive allosteric modulator of α7 nicotinic acetylcholine receptors, 3-furan-2-yl-<i>N-p</i>-tolyl-acrylamide, enhances memory processes and stimulates ERK1/2 phosphorylation in mice

Published by

Behavioural Brain Research

Summary

journal-article

The Stimulatory Effect of Strontium Ions on Phytoestrogens Content in Glycine max (L.) Merr

Published by

Molecules

Summary

journal-article

The Stimulatory effect of strontium ions on phytoestrogens content in glycine max (L.) Merr

Published by

Molecules

Summary

journal-article

The stimulatory effect of strontium ions on phytoestrogens content in <i>Glycine max</i> (L.) Merr

Published by

Molecules

Summary

journal-article

The Stimulatory Effect of Strontium Ions on Phytoestrogens Content in <i>Glycine max</i> (L.) Merr

Published by

Molecules

Summary

journal-article

Activation of β2-adrenergic receptor by (R,R')-4'-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells.

Summary

journal-article

Activation of β2-adrenergic receptor by (R,R')-4'-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells

Published by

Cellular Signalling

Summary

journal-article

Activation of <i>β</i>2-adrenergic receptor by (<i>R,R’</i>)-4’-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells

Published by

Cellular Signalling

Summary

journal-article

(R,R′)-4′-methoxy-1-naphthylfenoterol targets GPR55-mediated ligand internalization and impairs cancer cell motility

Summary

journal-article

(R,R')-4'-methoxy-1-naphthylfenoterol targets GPR55-mediated ligand internalization and impairs cancer cell motility

Published by

Biochemical Pharmacology

Summary

journal-article

Biological mosaics - oligomerization of G protein-coupled receptors

Published by

Biochemistry & Pharmacology

Summary

journal-article

Homo- and hetero-oligomerization of β2-adrenergic receptor in receptor trafficking, signaling pathways and receptor pharmacology

Published by

Cellular Signalling

Summary

journal-article

Homo- and hetero-oligomerization of β<inf>2</inf>-adrenergic receptor in receptor trafficking, signaling pathways and receptor pharmacology

Published by

Cellular Signalling

Summary

journal-article

Antitumor activity of (R,R’)-4-methoxy-1-naphthylfenoterol in a rat C6 glioma xenograft model in the mouse

Published by

Pharmacology Research and Perspectives

Summary

journal-article

Antitumor activity of (R,R’)-4-methoxy-1-naphthylfenoterol in a rat C6 glioma xenograft model in the mouse

Published by

Pharmacology Research & Perspectives

Summary

journal-article

Antitumor activity of (<i>R,R’</i>)-4-methoxy-1-naphthylfenoterol in a rat C6 glioma xenograft model in the mouse

Published by

Pharmacology Research & Perspectives

Summary

journal-article

Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7

Summary

journal-article

Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7

Published by

Journal of Virology

Summary

journal-article

Effects of human papillomavirus early proteins on transcriptional activity of the S100a8 gene

Published by

Warsaw University of Life Sciences

Summary

dissertation-thesis

Novel keratin 14 hotspot mutation in Dowling-Meara type of epidermolysis bullosa simplex: Strategy to avoid KRT14 pseudogene amplification by a simple approach

Summary

journal-article

Novel keratin 14 hotspot mutation in Dowling-Meara type of epidermolysis bullosa simplex: Strategy to avoid KRT14 pseudogene amplification by a simple approach

Published by

Journal of Dermatological Science

Summary

journal-article

Artur Wnorowski