Atul Deshmukh

Work

Københavns Universitet

Denmark

University of Copenhagen
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Associate Professor, Group Leader

Denmark

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University of Copenhagen
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Associate Professor

Denmark

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University of Copenhagen
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Senior post doc

Denmark

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Max-Planck-Institut für Biochemie
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Post doctoral fellow

Germany

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Universidade Estadual de Campinas
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Visiting scientist

Brazil

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RD college of pharmacy
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Lecturer/teacher pharmacology and pharmaceutical sciences

India

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Education

Karolinska Institutet
Sweden

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PhD in Medical Sciences

Hogskolan i Skovde
Sweden

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Masters in Molecular Biology and Biotechnology

Publications

Integrated single‐cell functional‐proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof‐of‐principle study

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The Journal of Physiology

Summary

journal-article

Integrated single-cell functional-proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy

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Journal of Physiology

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journal-article

Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise

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Science Advances

Summary

journal-article

Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise

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Science Advances

Summary

journal-article

Dysregulated skeletal muscle myosin super-relaxation and energetics in male participants with type 2 diabetes mellitus

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Diabetologia

Summary

journal-article

Global proteomics reveals distinct muscle adaptations to menstrual cycle phase-based sprint interval training in endurance-trained females

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Molecular & Cellular Proteomics

Summary

journal-article

Fiber Type–Specific Adaptations to Exercise Training in Human Skeletal Muscle

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Scandinavian Journal of Medicine and Science in Sports

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Human skeletal muscle fiber heterogeneity beyond myosin heavy chains

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Nature Communications

Summary

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Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake

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Cell Reports Medicine

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Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration

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Cell Reports

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Muscle Cathepsin B treatment improves behavioral and neurogenic deficits in a mouse model of Alzheimer's Disease

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bioRxiv

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NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging

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Cell Metabolism

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journal-article

Salivary proteomics and metaproteomics identifies distinct molecular and taxonomic signatures of type-2 diabetes

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Microbiome

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journal-article

Skeletal muscle Rac1 mediates exercise training adaptations towards muscle glycogen resynthesis and protein synthesis

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Redox Biology

Summary

journal-article

Menstrual Cycle Phase-Based Interval Training Yields Distinct Muscle Changes in Female Athletes

Summary

preprint

Integrated single cell functional-proteomic profiling of human skeletal muscle reveals a shift in cellular specificity in nemaline myopathy

Summary

preprint

Beta2‐Adrenergic Stimulation Induces Resistance Training‐Like Adaptations in Human Skeletal Muscle: Potential Role of KLHL41

Published by

Scandinavian Journal of Medicine & Science in Sports

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journal-article

Beta2-Adrenergic Stimulation Induces Resistance Training-Like Adaptations in Human Skeletal Muscle

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Scandinavian Journal of Medicine & Science in Sports

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journal-article

Muscle fiber proteomics reveals sex- and fiber type-specific adaptations to resistance training

Summary

preprint

Harnessing the power of proteomics in precision diabetes medicine

Published by

Diabetologia

Summary

journal-article

Mass spectrometry‐based proteomics approaches to interrogate skeletal muscle adaptations to exercise

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Scandinavian Journal of Medicine & Science in Sports

Summary

journal-article

Mass spectrometry-based proteomics approaches to interrogate skeletal muscle adaptations to exercise

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Scandinavian Journal of Medicine and Science in Sports

Summary

journal-article

Exercise-induced crosstalk between immune cells and adipocytes in humans

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Cell Reports Medicine

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GLP-1-directed NMDA receptor antagonism for obesity treatment

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Nature

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Lanifibranor Reduces Inflammation and Improves Dyslipidemia in Lysosomal Acid Lipase-Deficient Mice

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Gastro Hep Advances

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Plasma proteome profiling reveals metabolic and immunologic differences between Anorexia Nervosa subtypes

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Metabolism: Clinical and Experimental

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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment

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Science Advances

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High-throughput proteomics uncovers exercise training and type 2 diabetes–induced changes in human white adipose tissue

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Science Advances

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High-throughput proteomics uncovers exercise training and type 2 diabetes-induced changes in human white adipose tissue

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Science Advances

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journal-article

CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

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Molecular Metabolism

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journal-article

Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients – A randomized crossover trial

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Metabolism

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Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients - A randomized crossover trial

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Metabolism

Summary

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High-intensity interval training remodels the proteome and acetylome of human skeletal muscle

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eLife

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High-intensity interval training remodels the proteome and acetylome of human skeletal muscle

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eLife

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Exercise suppresses tumor growth independent of high fat food intake and associated immune dysfunction

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Scientific Reports

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Exercise suppresses tumor growth independent of high fat food intake and associated immune dysfunction

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Scientific Reports

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Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation

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Molecular & Cellular Proteomics

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Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation

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Molecular and Cellular Proteomics

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Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics

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STAR Protocols

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Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics

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STAR Protocols

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The proteomic profile of the human myotendinous junction

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iScience

Summary

journal-article

The proteomic profile of the human myotendinous junction

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iScience

Summary

journal-article

Illumination of the endogenous insulin-regulated TBC1D4 interactome in human skeletal muscle

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Diabetes

Summary

journal-article

Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

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Cell Reports Medicine

Summary

journal-article

Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

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Cell Reports

Summary

journal-article

Insulin and 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Differentially Regulate the Skeletal Muscle Cell Secretome

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Proteomes

Summary

journal-article

Insulin and 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Differentially Regulate the Skeletal Muscle Cell Secretome

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Proteomes

Summary

journal-article

Insulin and 5-aminoimidazole-4-carboxamide ribonucleotide (Aicar) differentially regulate the skeletal muscle cell secretome

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Proteomes

Summary

journal-article

Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes and normal tissues

Summary

other

Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

Published by

Cell Reports

Summary

journal-article

Author Correction: Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

Published by

Nature Communications

Summary

journal-article

High-Intensity Interval Training Remodels the Proteome and Acetylome of Human Skeletal Muscle

Summary

preprint

Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

Published by

Nature Communications

Summary

journal-article

Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

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Nature Communications

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Discovery of thymosin β4 as a human exerkine and growth factor

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American Journal of Physiology: Cell Physiology

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journal-article

Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473

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Nature Metabolism

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Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473.

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Nature metabolism

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Atorvastatin for prevention of disease progression and hospitalisation in liver cirrhosis

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BMJ Open

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A Multi-Omics Approach to Liver Diseases

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O M I C S: A Journal of Integrative Biology

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journal-article

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

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Cell Metabolism

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journal-article

Protein Aggregation Capture on Microparticles Enables Multipurpose Proteomics Sample Preparation.

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Molecular & cellular proteomics : MCP

Summary

journal-article

Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation

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Molecular and Cellular Proteomics

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Mechanisms preserving insulin action during high dietary fat intake

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Cell Metabolism

Summary

journal-article

Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition

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Proteomics

Summary

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Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition

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Proteomics

Summary

journal-article

Progressive resistance training in head and neck cancer patients undergoing concomitant chemoradiotherapy

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Laryngoscope Investigative Otolaryngology

Summary

journal-article

Insulin-stimulated glucose uptake in healthy and insulin-resistant skeletal muscle.

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Hormone molecular biology and clinical investigation

Summary

journal-article

Diacylglycerol kinase-δ regulates AMPK signaling, lipid metabolism, and skeletal muscle energetics

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American Journal of Physiology: Endocrinology and Metabolism

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journal-article

Proteomics of Skeletal Muscle: Focus on Insulin Resistance and Exercise Biology.

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Proteomes

Summary

journal-article

Proteomics of Skeletal Muscle: Focus on Insulin Resistance and Exercise Biology

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Proteomes

Summary

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Secretome Analysis of Lipid-Induced Insulin Resistance in Skeletal Muscle Cells by a Combined Experimental and Bioinformatics Workflow.

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Insulin-stimulated glucose uptake in healthy and insulin-resistant skeletal muscle.

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Diacylglycerol Kinase δ Regulates AMPK Signaling, Lipid Metabolism and Skeletal Muscle Energetics.

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journal-article

Secretome Analysis of Lipid-Induced Insulin Resistance in Skeletal Muscle Cells by a Combined Experimental and Bioinformatics Workflow

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Journal of Proteome Research

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Deep proteomics of mouse skeletal muscle enables quantitation of protein isoforms, metabolic pathways and transcription factors

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Molecular and Cellular Proteomics

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Absolute quantitative profiling of the key metabolic pathways in slow and fast skeletal muscle.

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Journal of proteome research

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Absolute quantitative profiling of the key metabolic pathways in slow and fast skeletal muscle

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Journal of Proteome Research

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Single muscle fiber proteomics reveals unexpected mitochondrial specialization.

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EMBO reports

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Single muscle fiber proteomics reveals unexpected mitochondrial specialization

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E M B O Reports

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journal-article

Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice.

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Diabetes

Summary

journal-article

Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice

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Diabetes

Summary

journal-article

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

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American Journal of Physiology: Endocrinology and Metabolism

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journal-article

Direct effects of FGF21 on glucose uptake in human skeletal muscle

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Diabetes - Metabolism: Research and Reviews (Print Edition)

Summary

journal-article

Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle

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Diabetologia

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journal-article

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

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Cell Metabolism

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journal-article

Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle

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American Journal of Physiology: Endocrinology and Metabolism

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journal-article

Post-transcriptional gene silencing of ribosomal protein S6 kinase 1 restores insulin action in leucine-treated skeletal muscle.

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Cellular and molecular life sciences : CMLS

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journal-article

Post-transcriptional gene silencing of ribosomal protein S6 kinase 1 restores insulin action in leucine-treated skeletal muscle

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Cellular and molecular life sciences : CMLS

Summary

journal-article

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity.

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Nature genetics

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Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

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Nature Genetics

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Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling.

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Molecular endocrinology (Baltimore, Md.)

Summary

journal-article

Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling

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Molecular Endocrinology

Summary

journal-article

Exercise-induced phospho-proteins in skeletal muscle

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International Journal of Obesity

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journal-article

Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle.

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Diabetes

Summary

journal-article

Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle

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Diabetes

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journal-article

AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.

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Diabetes

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journal-article

AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.

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Diabetes

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Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle.

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Diabetes

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Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle

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Diabetes

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