Chong Li Ming

About

A theoretical physicist-turned biomedical engineer. One of two of my current research interests involves personalized patient therapeutics with small-data and mechanism-agnostic phenotypic medicine platforms. I am currently leading the computational team in a phase 2/3 trial on CURATE.AI-guided therapy for multiple myeloma, a type of hematological malignancy (NCT03759093), in collaboration with Prof. Chng Wee Joo and Dr. Sanjay de Mel at the National University Cancer Institute, Singapore (NCIS). Additionally, under the PRECISE CURATE.AI pilot clinical trial (NCT04522284), I am leading the computational team for a prospective CURATE.AI-guided targeted therapy cohort for Waldenström macroglobulinemia, another type of hematological malignancy. Additionally, I am investigating unconventional solutions for medical problems at the intersection point of Physics, Engineering, and Medicine. As a part of the research effort to personalize radiotherapy, I have proposed a perspective piece in the British Journal of Cancer (IF: 8.1) on a potential new workflow for personalization of radiotherapy with CURATE, and it was accepted based on clinicians’ review. Currently, I am exploring the potential of CURATE-guided radiotherapy through in-depth physical and biological studies on novel response markers, as well as in silico modelling work, in collaboration with the NUS Mechanobiology Institute, the National Cancer Centre Singapore (NCCS), and NCIS.

Work

National University of Singapore
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Research Fellow

Singapore

Education

National University of Singapore
Singapore

Doctor of Philosophy

National University of Singapore
Singapore

Master of Science (by research)

National University of Singapore
Singapore

Bachelor of Science (Honours)

Publications

Flash optimization of drug combinations for Acinetobacter baumannii with IDentif.AI-AMR

Published by

npj Antimicrobials and Resistance

Summary

journal-article

Personalized dose selection for the first Waldenström macroglobulinemia patient on the PRECISE CURATE.AI trial

Published by

npj Digital Medicine

Summary

journal-article

Radiation therapy with phenotypic medicine: towards N-of-1 personalization

Published by

British Journal of Cancer

Summary

journal-article

N-of-1 medicine

Published by

Singapore Medical Journal

Summary

journal-article

Nanoparticles for Enhanced Radiotherapy and Imaging Applications

Published by

Nanomaterials for Cancer Detection Using Imaging Techniques and Their Clinical Applications

Summary

other

Recent advances in radiation therapy and photodynamic therapy

Published by

Applied Physics Reviews

Summary

journal-article