Darren Thompson

Work

University of Idaho - Coeur d'Alene
|

Adjunct Professor of Chemistry

US

Peptidaho Research Consortium
|

CEO/President

US

Scripps Research Institute
|

post-doc/research associate

US

University of California, Santa Cruz

US

Gryphon Sciences

US

Education

University of California Santa Cruz
United States of America

PhD

Publications

Native Chemical Ligation of Peptides and Proteins

Published by

Current Protocols in Chemical Biology

Summary

journal-article

Nanoparticle cellular uptake by dendritic wedge peptides: achieving single peptide facilitated delivery

Published by

Nanoscale

Summary

journal-article

Arginine selective reagents for ligation to peptides and proteins

Published by

J. Pept. Sci.

Summary

journal-article

Adapter reagents for protein site specific dye labeling

Published by

Biopolymers

Summary

journal-article

Selecting improved peptidyl motifs for cytosolic delivery of disparate protein and nanoparticle materials

Published by

ACS nano

Summary

journal-article

Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR

Published by

Nature chemical biology

Summary

journal-article

INCORPORATION OF A DISULFIDE MIMIC INTO AN FC AFFINITY PEPTIDE: SYNTHESIS AND BINDING

Published by

BIOPOLYMERS

Summary

conference-paper

Pineal-specific agouti protein regulates teleost background adaptation

Published by

Proceedings of the National Academy of Sciences

Summary

journal-article

Phosphodiesterase inhibitor-dependent inverse agonism of agouti-related protein on melanocortin 4 receptor in sea bass (Dicentrarchus labrax)

Published by

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Summary

journal-article

New ligands for melanocortin receptors

Published by

International Journal of Obesity

Summary

journal-article

A $β$-defensin mutation causes black coat color in domestic dogs

Published by

Science

Summary

journal-article

A POMC variant implicates $β$-melanocyte-stimulating hormone in the control of human energy balance

Published by

Cell metabolism

Summary

journal-article

Chimeras of the agouti-related protein: Insights into agonist and antagonist selectivity of melanocortin receptors

Published by

Peptides

Summary

journal-article

N-terminal modification of RANTES and methods of use

Summary

other

derivatives effectively block the inflammatory effects of RANTES, and are useful for the treatment of asthma, allergic rhinitis, atopic dermatitis, atheroma/atherosclerosis, and rheumatoid arthritis, hiv

Summary

other

Structures of the agouti signaling protein

Published by

Journal of molecular biology

Summary

journal-article

Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors

Published by

Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Inverse agonist activity of agouti and agouti-related protein

Published by

Peptides

Summary

journal-article

Peptoid mimics of agouti related protein

Published by

Bioorganic & Medicinal Chemistry Letters

Summary

journal-article

GLENN L. MILLHAUSER," JOE C. McNULTY," PILGRIM J. JACKSON

Published by

The Melanocortin System

Summary

journal-article

Loops and Links: Structural Insights into the Remarkable Function of the Agouti-Related Protein

Published by

Annals of the New York Academy of Sciences

Summary

journal-article

Dap-SL: a new site-directed nitroxide spin labeling approach for determining structure and motions in synthesized peptides and proteins

Published by

FEBS Letters

Summary

journal-article

Design, Pharmacology, and NMR Structure of a Minimized Cystine Knot with Agouti-Related Protein Activity †

Published by

Biochemistry

Summary

journal-article

A high-resolution NMR structure of AGRP [87-132]: Examining the molecular determinants of metabolism

Published by

BIOPHYSICAL JOURNAL

Summary

conference-paper

Rapid modular total chemical synthesis of chemokines based on genome sequence data

Published by

Peptides Frontiers of Peptide Science

Summary

book-chapter

Rational design and NMR structure of a equipotent minimized AGRP analogue

Published by

Biophysical Journal

Summary

conference-paper

Rational development of an anti-HIV protein active at low picomolar concentrations

Published by

Peptides for the New Millennium

Summary

book-chapter

Solid phase protein synthesis by chemical ligation of unprotected peptide segments in aqueous solution

Published by

Peptides Frontiers of Peptide Science

Summary

book-chapter

CCR2 and CCR5 receptor-binding properties of herpesvirus-8 vMIP-II based on sequence analysis and its solution structure

Published by

European Journal of Biochemistry

Summary

journal-article

Glandular disorders; computer model

Summary

other

Block the inflammatory effects of rantes, and are useful for the treatment of asthma, allergic rhinitis, atopic dermatitis, atheroma/atherosclerosis, rheumatoid arthritis and hiv infections

Summary

other

High-Resolution NMR Structure of the Chemically-Synthesized Melanocortin Receptor Binding Domain AGRP(87−132) of the Agouti-Related Protein † , ‡

Published by

Biochemistry

Summary

journal-article

Comparison of the Structure of vMIP-II with Eotaxin-1, RANTES, and MCP-3 Suggests a Unique Mechanism for CCR3 Activation † , ‡

Published by

Biochemistry

Summary

journal-article

Presentation of chemokine SDF-1$α$ by fibronectin mediates directed migration of T cells

Published by

Blood

Summary

journal-article

NMR structure of a minimized human agouti related protein prepared by total chemical synthesis

Published by

FEBS Letters

Summary

journal-article

Total chemical synthesis and high-resolution crystal structure of the potent anti-HIV protein AOP-RANTES

Published by

Chemistry & Biology

Summary

journal-article

Aminooxypentane-RANTES, an inhibitor of R5 human immunodeficiency virus type 1, increases the interferon gamma to interleukin 10 ratio without impairing cellular proliferation

Published by

AIDS research and human retroviruses

Summary

journal-article

CELL BIOLOGY-IMMUNOLOGY-PATHOLOGY-The chemokine receptor antagonist AOP-RANTES reduces monocyte infiltration in experimental glomerulonephritis

Published by

Kidney International

Summary

journal-article

Characterization of Agouti-related protein binding to melanocortin receptors

Published by

Molecular Endocrinology

Summary

journal-article

Contribution of melanocortin receptor exoloops to Agouti-related protein binding

Published by

Journal of Biological Chemistry

Summary

journal-article

Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells

Published by

The Journal of clinical investigation

Summary

journal-article

Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants

Published by

Journal of virology

Summary

journal-article

The chemokine receptor antagonist AOP-RANTES reduces monocyte infiltration in experimental glomerulonephritis

Published by

Kidney international

Summary

journal-article

6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3$β$ receptor CCR7

Published by

The Journal of cell biology

Summary

journal-article

Accessibility of selenomethionine proteins by total chemical synthesis: structural studies of human herpesvirus-8 MIP-II

Published by

FEBS Letters

Summary

journal-article

Action or AOP-RANTES as a HIV-1 inhibitor without impairing cellular proliferation while increasing IFNgamma/IL-10 ratio in vitro

Published by

EUROPEAN CYTOKINE NETWORK

Summary

conference-paper

BIOLOGICAL ACTIVITIES OF CHEMICALLY SYNTHESIZED VARIANT OF AGOUTI-RELATED PROTEIN (AGRP)

Published by

Journal of Pediatric Gastroenterology and Nutrition

Summary

journal-article

Chemokines and the arrest of lymphocytes rolling under flow conditions

Published by

Science

Summary

journal-article

Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1$α$, a potent ligand for the HIV-1 “fusin” coreceptor

Published by

Proceedings of the National Academy of Sciences

Summary

journal-article

Genetic subtype-independent inhibition of human immunodeficiency virus type 1 replication by CC and CXC chemokines

Published by

Journal of virology

Summary

journal-article

In vivo inhibition of CC and CX3C chemokine--induced leukocyte infiltration and attenuation of glomerulonephritis in Wistar-Kyoto (WKY) rats by vMIP-II

Published by

The Journal of experimental medicine

Summary

journal-article

Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

Published by

Proceedings of the National Academy of Sciences

Summary

journal-article

Chemically synthesized SDF-1$α$ analogue, N33A, is a potent chemotactic agent for CXCR4/Fusin/LESTR-expressing human leukocytes

Published by

Journal of Biological Chemistry

Summary

journal-article

Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5

Published by

The Journal of experimental medicine

Summary

journal-article

The total chemical synthesis of L-and D-superoxide dismutase

Published by

Protein Engineering

Summary

journal-article