Davide Rossi

About

Prof. Rossi serves as an Associate Professor at the Faculty of Biomedicine, Università della Svizzera italiana. He is also the Head of the Laboratory of Experimental Hematology at the Institute of Oncology Research, Deputy Head at the Clinic of Hematology of the Oncology Institute of Southern Switzerland, and oversees the Lymphoid Tumors Program there. Prof. Rossi has earned national and international recognition as a scientist, particularly in the fields of lymphoma and chronic lymphocytic leukemia, as evidenced by his extensive publication record. He has received grants from prestigious organizations such as the European Research Council, the Swiss National Science Foundation, the Swiss Cancer League, the Leukemia & Lymphoma Society, and various other national and international bodies. He serves as a member of the Scientific Committee of the Leukemia Project Group within the Swiss Group for Clinical Cancer Research (SAKK). Additionally, he acts as the Principal Investigator for institutional and national clinical trials focused on chronic lymphocytic leukemia and lymphoma. Prof. Rossi has contributed to the 5th Edition of the WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. He is frequently invited to speak at international meetings and serves as a member of the International Workshop on Chronic Lymphocytic Leukemia. Additionally, he is involved in the Organizing and Program Committees of major events such as the International Conference on Malignant Lymphoma, the Congress of the European Hematology Association, and the European Society of Medical Oncology Congress. Prof. Rossi actively engages in a broad network of national and international collaborations, as evidenced by numerous collaboration-driven publications. In recognition of his research contributions in the field of lymphomas, he has received prestigious awards such as the "Sivia Fiocco" prize from the Italian National Academy of Science, the "Ellermann" prize from the Swiss Society of Hematology, and the Robert Wenner Award from the Swiss Cancer League. Prof. Rossi focuses on the molecular pathogenesis of mature B-cell tumors, making significant contributions to the field. His key achievements include: (i) discovering several driver mutations in chronic lymphocytic leukemia and establishing their role as prognostic biomarkers; (ii) elucidating the molecular underpinnings of high-risk chronic lymphocytic leukemia, including refractory and transformed forms of the disease; (iii) developing prognostic scores for chronic lymphocytic leukemia; (iv) identifying driver genes and genetic subtypes of marginal zone lymphoma that aid in disease classification; and (v) advancing the clinical application of circulating tumor DNA in classic Hodgkin lymphoma. Many of his discoveries have been integrated into the 5th Edition of the WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. Overall, Prof. Rossi is author of 365 peer reviewed publications (citations: 34272; h-index: 91).

Work

Università della Svizzera italiana
|

Associate Professor of Medicine

Switzerland

Oncology Institute of Southern Switzerland
|

Deputy Head

Switzerland

Institute of Oncology Research
|

Group Leader

Switzerland

Azienda Ospedaliero Universitaria Maggiore della Carita
|

Head of the clinical program for lymphoproliferative neoplasms

Italy

University of Eastern Piedmont Amadeo Avogadro
|

Assistant Professor of Hematology

Italy

Azienda Ospedaliero Universitaria Maggiore della Carita
|

Senior Physician

Italy

Azienda Ospedaliero Universitaria Maggiore della Carita
|

Attending Clinician

Italy

Education

University of Eastern Piedmont Amadeo Avogadro
Italy

MD

Publications

Ibrutinib as first line therapy in chronic lymphocytic leukemia patients over 80 years old: A retrospective real-life multicenter Italian cohort.

Published by

Hematological oncology

Summary

journal-article

Activity of venetoclax in patients with relapsed or refractory chronic lymphocytic leukaemia: analysis of the VENICE-1 multicentre, open-label, single-arm, phase 3b trial.

Published by

The Lancet. Oncology

Summary

journal-article

Proliferative History Is a Novel Driver of Clinical Outcome in Splenic Marginal Zone Lymphoma

Summary

preprint

ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms.

Published by

Molecular cancer therapeutics

Summary

journal-article

Low incidence of tumor lysis syndrome in elderly patients with chronic lymphocytic leukemia treated with venetoclax under real-world conditions: results from the prospective observational VeRVe study.

Published by

Annals of hematology

Summary

journal-article

IELSG38: phase II trial of front-line chlorambucil plus subcutaneous rituximab induction and maintenance in mucosa-associated lymphoid tissue lymphoma.

Published by

Haematologica

Summary

journal-article

P1225: CYLD, A NOVEL REGULATOR OF SPLENIC MARGINAL ZONE LYMPHOMA PATHOGENESIS

Published by

HemaSphere

Summary

journal-article

P594: THE CXCR4-LOW/CD5-HIGH PROLIFERATIVE FRACTION IS ENRICHED IN BTK MUTATIONS AND ANTICIPATES RELAPSE IN IBRUTINIB-TREATED CLL

Published by

HemaSphere

Summary

journal-article

PB1938: REAL WORLD EFFECTIVENESS AND SAFETY OF VENETOCLAX IN COMBINATION WITH OBINUTUZUMAB IN TREATMENT NAIVE CLL PATIENTS – DATA FROM THE OBSERVATIONAL STUDY VERVE

Published by

HemaSphere

Summary

journal-article

S143: NATURAL CLONAL EVOLUTION OF CHRONIC LYMPHOCYTIC LEUKEMIA WITH BIMODAL CD49D EXPRESSION REVEALS CD49D PLASTICITY

Published by

HemaSphere

Summary

journal-article

S147: EFFICACY AND SAFETY RESULTS OF MOLTO, A MULTICENTER, OPEN LABEL, PHASE II CLINICAL TRIAL EVALUATING VENETOCLAX, ATEZOLIZUMAB AND OBINUTUZUMAB COMBINATION IN RICHTER SYNDROME

Published by

HemaSphere

Summary

journal-article

SOHO State of the Art Updates and Next Questions | Treatment of Richter's Transformation.

Published by

Clinical lymphoma, myeloma & leukemia

Summary

journal-article

Targeting CD19-positive lymphomas with the antibody-drug conjugate (ADC) loncastuximab tesirine: preclinical evidence as single agent and as combinatorial approach

Summary

preprint

The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy.

Published by

Haematologica

Summary

journal-article

XPO1 mutations identify early-stage CLL characterized by shorter time to first treatment and enhanced BCR signalling.

Published by

British journal of haematology

Summary

journal-article

Prevalence of amyloid in ligamentum flavum of patients with lumbar spinal stenosis.

Published by

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

Summary

journal-article

Special issue on circulating tumor DNA: Introductory editorial.

Published by

Seminars in hematology

Summary

journal-article

Marginal zone lymphomas.

Published by

Hematological oncology

Summary

journal-article

First-Line Venetoclax Combinations in Chronic Lymphocytic Leukemia.

Published by

The New England journal of medicine

Summary

journal-article

<i>TP53</i> Mutations and Clinical Outcome in Chronic Lymphocytic Leukemia: Is a Threshold Still Needed?

Published by

HemaSphere

Summary

journal-article

The time to first treatment is an independent predictor of overall survival in chronic lymphocytic leukemia.

Published by

American journal of hematology

Summary

journal-article

Acquired haemophilia A in southern Switzerland from 2013 to 2019: a case series.

Published by

Swiss medical weekly

Summary

journal-article

Correction: Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Published by

Leukemia

Summary

journal-article

ERBB4-mediated signaling is a mediator of resistance to BTK and PI3K inhibitors in B cell lymphoid neoplasms

Summary

preprint

P597: XPO1 MUTATIONS IDENTIFY EARLY STAGE CLL CHARACTERIZED BY SHORTER TIME TO FIRST TREATMENT AND ENHANCED BCR SIGNALING

Published by

HemaSphere

Summary

journal-article

Distinct Hodgkin lymphoma subtypes defined by noninvasive genomic profiling.

Published by

Nature

Summary

journal-article

PI3Kδ activation, IL6 over-expression, and CD37 loss cause resistance to the targeting of CD37-positive lymphomas with the antibody-drug conjugate naratuximab emtansine

Summary

preprint

Baseline circulating tumour DNA and interim PET predict response in relapsed/refractory classical Hodgkin lymphoma.

Published by

British journal of haematology

Summary

journal-article

Correction: "The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms" Leukemia. 2022 Jul;36(7):1720-1748.

Published by

Leukemia

Summary

journal-article

ETS1 phosphorylation at threonine 38 is associated with the cell of origin of diffuse large B cell lymphoma and sustains the growth of tumour cells.

Published by

British journal of haematology

Summary

journal-article

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Published by

Leukemia

Summary

journal-article

Genetics and epigenetics of CLL.

Published by

Leukemia & lymphoma

Summary

journal-article

HTGQC and shinyHTGQC: an R package and shinyR application for quality controls of HTG EDGE-seq protocols.

Published by

GigaByte (Hong Kong, China)

Summary

journal-article

In vitro anti-lymphoma activity of the first-in-class pan-NOTCH transcription inhibitor CB-103.

Published by

British journal of haematology

Summary

journal-article

Efficacy of front-line ibrutinib versus fludarabine, cyclophosphamide, and rituximab in patients with chronic lymphocytic leukemia: A retrospective multicenter "Real-World" study.

Published by

American journal of hematology

Summary

journal-article

Genomic profiling for clinical decision making in lymphoid neoplasms.

Published by

Blood

Summary

journal-article

Mechanisms of resistance to venetoclax.

Published by

Blood

Summary

journal-article

Mechanisms of resistance to venetoclax

Published by

Blood

Summary

journal-article

Resistance to PI3Kδ inhibitors in marginal zone lymphoma can be reverted by targeting the IL-6/PDGFRA axis.

Published by

Haematologica

Summary

journal-article

Long-term benefit of IGHV mutated patients in a real-life multicenter cohort of FCR-treated chronic lymphocytic leukemia.

Published by

Hematological oncology

Summary

journal-article

Detection of early seeding of Richter transformation in chronic lymphocytic leukemia.

Published by

Nature medicine

Summary

journal-article

Bacterial infection-driven lymphomagenesis.

Published by

Current opinion in oncology

Summary

journal-article

SAKK 35/15: a phase 1 trial of obinutuzumab in combination with venetoclax in patients with previously untreated follicular lymphoma.

Published by

Blood advances

Summary

journal-article

Anatomical heterogeneity of residual disease in chronic lymphocytic leukemia treated with ibrutinib.

Published by

Hematological oncology

Summary

journal-article

Ibrutinib dose intensity in high-risk chronic lymphocytic leukemia.

Published by

Hematological oncology

Summary

journal-article

Controversies in the Interpretation of Liquid Biopsy Data in Lymphoma.

Published by

HemaSphere

Summary

journal-article

Marginal-Zone Lymphomas. Reply.

Published by

The New England journal of medicine

Summary

journal-article

Chemotherapy after PD-1 inhibitors in relapsed/refractory Hodgkin lymphoma: Outcomes and clonal evolution dynamics.

Published by

British journal of haematology

Summary

journal-article

Biology and Treatment of Richter Transformation.

Published by

Frontiers in oncology

Summary

journal-article

Hodgkin Lymphoma: Recent Progress in Overall Management

Summary

book

Genetic and phenotypic attributes of splenic marginal zone lymphoma.

Published by

Blood

Summary

journal-article

Marginal zone lymphoma: present status and future perspectives.

Published by

Haematologica

Summary

journal-article

Richter Syndrome.

Published by

Current oncology reports

Summary

journal-article

A new triplet for chronic lymphocytic leukaemia: zanubrutinib-venetoclax-obinutuzumab.

Published by

The Lancet. Haematology

Summary

journal-article

Circulating tumor DNA for comprehensive noninvasive monitoring of lymphoma treated with ibrutinib plus nivolumab.

Published by

Blood advances

Summary

journal-article

Circulating Tumor DNA in Lymphoma: Principles and Future Directions.

Published by

Blood cancer discovery

Summary

journal-article

IRF4 L116R mutation promotes proliferation of chronic lymphocytic leukemia B cells inducing MYC.

Published by

Hematological oncology

Summary

journal-article

Lymphocyte Doubling Time As A Key Prognostic Factor To Predict Time To First Treatment In Early-Stage Chronic Lymphocytic Leukemia.

Published by

Frontiers in oncology

Summary

journal-article

<i>TP53</i> Mutations with Low Variant Allele Frequency Predict Short Survival in Chronic Lymphocytic Leukemia.

Published by

Clinical cancer research : an official journal of the American Association for Cancer Research

Summary

journal-article

Enhanced detection of minimal residual disease by targeted sequencing of phased variants in circulating tumor DNA.

Published by

Nature biotechnology

Summary

journal-article

Multiregional sequencing and circulating tumour DNA analysis provide complementary approaches for comprehensive disease profiling of small lymphocytic lymphoma.

Published by

British journal of haematology

Summary

journal-article

Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma.

Published by

Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations.

Published by

Leukemia

Summary

journal-article

Co-occurrence and mutual exclusivity: what cross-cancer mutation patterns can tell us.

Published by

Trends in cancer

Summary

journal-article

Effectiveness of ibrutinib as first-line therapy for chronic lymphocytic leukemia patients and indirect comparison with rituximab-bendamustine: Results of study on 486 cases outside clinical trials.

Published by

American journal of hematology

Summary

journal-article

Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

TP53 disruption as a risk factor in the era of targeted therapies: A multicenter retrospective study of 525 chronic lymphocytic leukemia cases.

Published by

American journal of hematology

Summary

journal-article

Short Diagnosis-to-Treatment Interval Is Associated With Higher Circulating Tumor DNA Levels in Diffuse Large B-Cell Lymphoma.

Published by

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Summary

journal-article

Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study.

Published by

Haematologica

Summary

journal-article

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL.

Published by

Blood

Summary

journal-article

Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1.

Published by

Blood

Summary

journal-article

Assessment of the 4-factor score: Retrospective analysis of 586 CLL patients receiving ibrutinib. A campus CLL study.

Published by

American journal of hematology

Summary

journal-article

Long-Term Evaluation of Antiphospholipid Antibodies in Patients with COVID-19

Summary

preprint

Lymphocyte doubling time in chronic lymphocytic leukemia modern era: a real-life study in 848 unselected patients.

Published by

Leukemia

Summary

journal-article

Comparison of ibrutinib and idelalisib plus rituximab in real-life relapsed/resistant chronic lymphocytic leukemia cases.

Published by

European journal of haematology

Summary

journal-article

CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression.

Published by

Blood

Summary

journal-article

Genomic Instability and Clonal Evolution in Chronic Lymphocytic Leukemia: Clinical Relevance.

Published by

Journal of the National Comprehensive Cancer Network : JNCCN

Summary

journal-article

Survival risk score for real-life relapsed/refractory chronic lymphocytic leukemia patients receiving ibrutinib. A campus CLL study.

Published by

Leukemia

Summary

journal-article

Copanlisib synergizes with conventional and targeted agents including venetoclax in B- and T-cell lymphoma models.

Published by

Blood advances

Summary

journal-article

Frequency and clinical relevance of coding and noncoding NOTCH1 mutations in early stage Binet A chronic lymphocytic leukemia patients.

Published by

Hematological oncology

Summary

journal-article

Redefining the prognostic likelihood of chronic lymphocytic leukaemia patients with borderline percentage of immunoglobulin variable heavy chain region mutations.

Published by

British journal of haematology

Summary

journal-article

Biological and clinical implications of <i>BIRC3</i> mutations in chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

Bleeding prevalence in COVID-19 patients receiving intensive antithrombotic prophylaxis.

Published by

Journal of thrombosis and thrombolysis

Summary

journal-article

The development of liquid biopsy for research and clinical practice in lymphomas: Report of the 15‐ICML workshop on ctDNA

Published by

Hematological Oncology

Summary

journal-article

Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models.

Published by

Haematologica

Summary

journal-article

SOHO State of the Art Updates and Next Questions: Clonal Evolution in Chronic Lymphocytic Leukemia.

Published by

Clinical lymphoma, myeloma & leukemia

Summary

journal-article

Prospective long-term follow-up after first-line subcutaneous cladribine in hairy cell leukemia: a SAKK trial.

Published by

Blood advances

Summary

journal-article

How We Manage Patients With Chronic Lymphocytic Leukemia During the SARS-CoV-2 Pandemic.

Published by

HemaSphere

Summary

journal-article

Marginal Zone Lymphomas.

Published by

Cancer journal (Sudbury, Mass.)

Summary

journal-article

Reply to Aron P. Kater <i>et al</i>.

Published by

Haematologica

Summary

journal-article

International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

Epigenetic Trajectories of the Premalignant-to-Malignant Transition of Chronic Lymphocytic Leukemia.

Published by

Blood cancer discovery

Summary

journal-article

Genome-wide promoter methylation of hairy cell leukemia.

Published by

Blood advances

Summary

journal-article

Global variation in anastomosis and end colostomy formation following left-sided colorectal resection.

Published by

BJS open

Summary

journal-article

Reply to J. Wang et al.

Published by

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Summary

journal-article

The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models.

Published by

Haematologica

Summary

journal-article

Different time-dependent changes of risk for evolution in chronic lymphocytic leukemia with mutated or unmutated antigen B cell receptors.

Published by

Leukemia

Summary

journal-article

Integrated epigenomic and transcriptomic analysis reveals TP63 as a novel player in clinically aggressive chronic lymphocytic leukemia.

Published by

International journal of cancer

Summary

journal-article

Liquid biopsy in tissue-born lymphomas.

Published by

Swiss medical weekly

Summary

journal-article

Methods for Measuring ctDNA in Lymphomas.

Published by

Methods in molecular biology (Clifton, N.J.)

Summary

journal-article

Overview of non-coding mutations in chronic lymphocytic leukemia.

Published by

Molecular oncology

Summary

journal-article

The Bruton tyrosine kinase inhibitor zanubrutinib (BGB-3111) demonstrated synergies with other anti-lymphoma targeted agents.

Published by

Haematologica

Summary

journal-article

Quest of biomarkers for venetoclax-treated CLL.

Published by

Blood

Summary

journal-article

The development of liquid biopsy for research and clinical practice in lymphomas: Report of the 15-ICML workshop on ctDNA.

Published by

Hematological oncology

Summary

journal-article

Daratumumab for relapsed or refractory AL amyloidosis with high plasma cell burden.

Published by

Hematological oncology

Summary

journal-article

A laboratory-based scoring system predicts early treatment in Rai 0 chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

<i>KMT2D</i> mutations and <i>TP53</i> disruptions are poor prognostic biomarkers in mantle cell lymphoma receiving high-dose therapy: a FIL study.

Published by

Haematologica

Summary

journal-article

Late relapse in patients with diffuse large B-cell lymphoma: impact of rituximab on their incidence and outcome.

Published by

British journal of haematology

Summary

journal-article

Oprozomib in patients with newly diagnosed multiple myeloma.

Published by

Blood cancer journal

Summary

journal-article

Dynamic Risk Profiling Using Serial Tumor Biomarkers for Personalized Outcome Prediction.

Published by

Cell

Summary

journal-article

HIF-1α is over-expressed in leukemic cells from <i>TP53</i>-disrupted patients and is a promising therapeutic target in chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

The future of cell-free DNA testing to guide therapeutic decisions in B-cell lymphomas.

Published by

Current opinion in hematology

Summary

journal-article

Venetoclax plus daratumumab induce hematological CR and organ response in an AL amyloidosis patient with t(11;14).

Published by

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

Summary

journal-article

Differential genomic and transcriptomic events associated with high-grade transformation of Chronic Lymphocytic Leukemia

Summary

preprint

Novel insights into the genetics and epigenetics of MALT lymphoma unveiled by next generation sequencing analyses.

Published by

Haematologica

Summary

journal-article

Liquid biopsy in lymphoma.

Published by

Haematologica

Summary

journal-article

<i>FBXW7</i> is a biologically validated cancer driver gene for CLL.

Published by

Blood

Summary

journal-article

Genetic mutations in chronic lymphocytic leukemia: impact on clinical treatment.

Published by

Expert review of hematology

Summary

journal-article

Biology and treatment of Richter syndrome.

Published by

Blood

Summary

journal-article

Foreword.

Published by

European journal of internal medicine

Summary

journal-article

Melphalan dose in myeloma patients ≥65 years of age undergoing high-dose therapy and autologous stem cell transplantation: a multicentric observational registry study.

Published by

Bone marrow transplantation

Summary

journal-article

The involvement of microRNA in the pathogenesis of Richter syndrome.

Published by

Haematologica

Summary

journal-article

Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

Circulating Tumor DNA Measurements As Early Outcome Predictors in Diffuse Large B-Cell Lymphoma.

Published by

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Summary

journal-article

Toward a Risk-Tailored Therapeutic Policy in Mantle Cell Lymphoma.

Published by

Current oncology reports

Summary

journal-article

Immunoglobulin heavy chain variable region gene and prediction of time to first treatment in patients with chronic lymphocytic leukemia: Mutational load or mutational status? Analysis of 1003 cases.

Published by

American journal of hematology

Summary

journal-article

Predictive value of the CLL-IPI in CLL patients receiving chemo-immunotherapy as first-line treatment.

Published by

European journal of haematology

Summary

journal-article

Age-related clonal hematopoiesis and monoclonal B-cell lymphocytosis/chronic lymphocytic leukemia: a new association?

Published by

Haematologica

Summary

journal-article

Biallelic BIRC3 inactivation in chronic lymphocytic leukaemia patients with 11q deletion identifies a subgroup with very aggressive disease.

Published by

British journal of haematology

Summary

journal-article

Recent advances in understanding the biology of marginal zone lymphoma.

Published by

F1000Research

Summary

journal-article

Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukaemia.

Published by

The Journal of pathology

Summary

journal-article

Validation of a biological score to predict response in chronic lymphocytic leukemia patients treated front-line with bendamustine and rituximab.

Published by

Leukemia

Summary

journal-article

Circulating tumor DNA as a liquid biopsy in plasma cell dyscrasias.

Published by

Haematologica

Summary

journal-article

Circulating tumor DNA reveals genetics, clonal evolution, and residual disease in classical Hodgkin lymphoma.

Published by

Blood

Summary

journal-article

Clinical, pathological, and biological characterization of Richter syndrome developing after ibrutinib treatment for relapsed chronic lymphocytic leukemia.

Published by

Hematological oncology

Summary

journal-article

Lenalidomide maintenance in high risk chronic lymphocytic leukaemia: practice changing study or hypothesis generating approach?

Published by

The Lancet. Haematology

Summary

journal-article

Macitentan, a double antagonist of endothelin receptors, efficiently impairs migration and microenvironmental survival signals in chronic lymphocytic leukemia.

Published by

Oncotarget

Summary

journal-article

Mutational status of <i>IGHV</i> is the most reliable prognostic marker in trisomy 12 chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

NOTCH1 mutational status in chronic lymphocytic leukaemia: clinical relevance of subclonal mutations and mutation types.

Published by

British journal of haematology

Summary

journal-article

Increased SHISA3 expression characterizes chronic lymphocytic leukemia patients sensitive to lenalidomide.

Published by

Leukemia & lymphoma

Summary

journal-article

Drug-perturbation-based stratification of blood cancer.

Published by

The Journal of clinical investigation

Summary

journal-article

Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes.

Published by

Clinical cancer research : an official journal of the American Association for Cancer Research

Summary

journal-article

Mutations in the 3' untranslated region of <i>NOTCH1</i> are associated with low CD20 expression levels chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

Progressive telomere shortening is part of the natural history of chronic lymphocytic leukaemia and impacts clinical outcome: evidences from long term follow-up.

Published by

British journal of haematology

Summary

journal-article

Common nonmutational <i>NOTCH1</i> activation in chronic lymphocytic leukemia.

Published by

Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Recommended Guidelines for Validation, Quality Control, and Reporting of <i>TP53</i> Variants in Clinical Practice.

Published by

Cancer research

Summary

journal-article

Diffuse large B-cell lymphoma genotyping on the liquid biopsy.

Published by

Blood

Summary

journal-article

Comparison between the CLL-IPI and the Barcelona-Brno prognostic model: Analysis of 1299 newly diagnosed cases.

Published by

American journal of hematology

Summary

journal-article

Treatment of Richter's Syndrome.

Published by

Current treatment options in oncology

Summary

journal-article

The mutational landscape of chronic lymphocytic leukemia and its impact on prognosis and treatment.

Published by

Hematology. American Society of Hematology. Education Program

Summary

journal-article

PQR309 Is a Novel Dual PI3K/mTOR Inhibitor with Preclinical Antitumor Activity in Lymphomas as a Single Agent and in Combination Therapy.

Published by

Clinical cancer research : an official journal of the American Association for Cancer Research

Summary

journal-article

Richter syndrome: pathogenesis and management.

Published by

Seminars in oncology

Summary

journal-article

High prevalence of splenic marginal zone lymphoma among patients with acquired C1 inhibitor deficiency.

Published by

British journal of haematology

Summary

journal-article

Clinical impact of small subclones harboring NOTCH1, SF3B1 or BIRC3 mutations in chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

Integration of B-cell receptor-induced ERK1/2 phosphorylation and mutations of <i>SF3B1</i> gene refines prognosis in treatment-naïve chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

Adenosine signaling mediates hypoxic responses in the chronic lymphocytic leukemia microenvironment.

Published by

Blood advances

Summary

journal-article

Molecular pathogenesis of splenic and nodal marginal zone lymphoma.

Published by

Best practice & research. Clinical haematology

Summary

journal-article

Predictive and prognostic biomarkers in the era of new targeted therapies for chronic lymphocytic leukemia.

Published by

Leukemia & lymphoma

Summary

journal-article

NF-κB deregulation in splenic marginal zone lymphoma.

Published by

Seminars in cancer biology

Summary

journal-article

Validation of the CLL-IPI and comparison with the MDACC prognostic index in newly diagnosed patients.

Published by

Blood

Summary

journal-article

Decreased function of Fas and variations of the perforin gene in adult patients with primary immune thrombocytopenia.

Published by

British journal of haematology

Summary

journal-article

The genetics of nodal marginal zone lymphoma.

Published by

Blood

Summary

journal-article

Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors.

Published by

Haematologica

Summary

journal-article

Venetoclax: a new weapon to treat high-risk CLL.

Published by

The Lancet. Oncology

Summary

journal-article

Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature.

Published by

Oncotarget

Summary

journal-article

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

Published by

Haematologica

Summary

journal-article

Richter's syndrome: Novel and promising therapeutic alternatives.

Published by

Best practice & research. Clinical haematology

Summary

journal-article

Splenic marginal zone lymphoma: from genetics to management.

Published by

Blood

Summary

journal-article

The clinical implications of gene mutations in chronic lymphocytic leukaemia.

Published by

British journal of cancer

Summary

journal-article

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations.

Published by

Blood

Summary

journal-article

Clinical significance of bax/bcl-2 ratio in chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

The genotype of MLH1 identifies a subgroup of follicular lymphoma patients who do not benefit from doxorubicin: FIL-FOLL study.

Published by

Haematologica

Summary

journal-article

Inter- and intra-patient clonal and subclonal heterogeneity of chronic lymphocytic leukaemia: evidences from circulating and lymph nodal compartments.

Published by

British journal of haematology

Summary

journal-article

SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response.

Published by

The Journal of clinical investigation

Summary

journal-article

Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia.

Published by

The New England journal of medicine

Summary

journal-article

A phase II multi-center trial of pentostatin plus cyclophosphamide with ofatumumab in older previously untreated chronic lymphocytic leukemia patients.

Published by

Haematologica

Summary

journal-article

Low-dose alemtuzumab in refractory/relapsed chronic lymphocytic leukemia: Genetic profile and long-term outcome from a single center experience.

Published by

American journal of hematology

Summary

journal-article

Molecular prediction of durable remission after first-line fludarabine-cyclophosphamide-rituximab in chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

Prognostic relevance of MYD88 mutations in CLL: the jury is still out.

Published by

Blood

Summary

journal-article

The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells.

Published by

Oncotarget

Summary

journal-article

Epstein-Barr virus DNA load in chronic lymphocytic leukemia is an independent predictor of clinical course and survival.

Published by

Oncotarget

Summary

journal-article

XIII. Molecular pathogenesis of transformed lymphomas.

Published by

Hematological oncology

Summary

journal-article

Association between gene and miRNA expression profiles and stereotyped subset #4 B-cell receptor in chronic lymphocytic leukemia.

Published by

Leukemia & lymphoma

Summary

journal-article

Molecular deregulation of signaling in lymphoid tumors.

Published by

European journal of haematology

Summary

journal-article

Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.

Published by

Cancer cell

Summary

journal-article

Excessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset #8.

Published by

Blood

Summary

journal-article

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features.

Published by

Blood

Summary

journal-article

SAMHD1: a new gene for CLL.

Published by

Blood

Summary

journal-article

Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness.

Published by

Blood

Summary

journal-article

Ibrutinib-naïve chronic lymphocytic leukemia lacks Bruton tyrosine kinase mutations associated with treatment resistance.

Published by

Blood

Summary

journal-article

NOTCH1, SF3B1, BIRC3 and TP53 mutations in patients with chronic lymphocytic leukemia undergoing first-line treatment: correlation with biological parameters and response to treatment.

Published by

Leukemia & lymphoma

Summary

journal-article

Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia.

Published by

eLife

Summary

journal-article

Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

Role of MYD88 in lymphoplasmacytic lymphoma diagnosis and pathogenesis.

Published by

Hematology. American Society of Hematology. Education Program

Summary

journal-article

The NOTCH pathway is recurrently mutated in diffuse large B-cell lymphoma associated with hepatitis C virus infection.

Published by

Haematologica

Summary

journal-article

MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis.

Published by

Haematologica

Summary

journal-article

Molecular lesions of signalling pathway genes in clonal B-cell lymphocytosis with marginal zone features.

Published by

British journal of haematology

Summary

journal-article

Italian external and multicentric validation of the MD Anderson Cancer Center nomogram and prognostic index for chronic lymphocytic leukaemia patients: analysis of 1502 cases.

Published by

British journal of haematology

Summary

journal-article

Bendamustine and subcutaneous alemtuzumab combination is an effective treatment in relapsed/refractory chronic lymphocytic leukemia patients.

Published by

Haematologica

Summary

journal-article

Endothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptor.

Published by

PloS one

Summary

journal-article

NOTCH1 mutations identify a chronic lymphocytic leukemia patient subset with worse prognosis in the setting of a rituximab-based induction and consolidation treatment.

Published by

Annals of hematology

Summary

journal-article

Carfilzomib, cyclophosphamide, and dexamethasone in patients with newly diagnosed multiple myeloma: a multicenter, phase 2 study.

Published by

Blood

Summary

journal-article

High-throughput sequencing for the identification of NOTCH1 mutations in early stage chronic lymphocytic leukaemia: biological and clinical implications.

Published by

British journal of haematology

Summary

journal-article

Lymphocytosis and ibrutinib treatment of CLL.

Published by

Blood

Summary

journal-article

BCL2 mutation spectrum in B-cell non-Hodgkin lymphomas and patterns associated with evolution of follicular lymphoma.

Published by

Hematological oncology

Summary

journal-article

Bortezomib, melphalan, prednisone (VMP) versus melphalan, prednisone, thalidomide (MPT) in elderly newly diagnosed multiple myeloma patients: A retrospective case-matched study.

Published by

American journal of hematology

Summary

journal-article

CD49d is the strongest flow cytometry-based predictor of overall survival in chronic lymphocytic leukemia.

Published by

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Summary

journal-article

Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

High XBP1 expression is a marker of better outcome in multiple myeloma patients treated with bortezomib.

Published by

Haematologica

Summary

journal-article

Merkel cell carcinoma arising in inguinal lymph node in a patient with von Willebrand disease after multiple blood transfusions.

Published by

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

Summary

journal-article

Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition.

Published by

Leukemia

Summary

journal-article

Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: updated follow-up and improved survival.

Published by

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Summary

journal-article

Genetics of follicular lymphoma transformation.

Published by

Cell reports

Summary

journal-article

MYC network mutations in high-risk chronic lymphocytic leukaemia.

Published by

Hematological oncology

Summary

journal-article

Notch signaling in peripheral T-cell lymphoma: revelations from immunohistochemistry.

Published by

Leukemia & lymphoma

Summary

journal-article

Stereotyped subset #1 chronic lymphocytic leukemia: a direct link between B-cell receptor structure, function, and patients' prognosis.

Published by

American journal of hematology

Summary

journal-article

Genome-wide DNA profiling identifies clonal heterogeneity in marginal zone lymphomas.

Published by

British journal of haematology

Summary

journal-article

HLA-G is a component of the chronic lymphocytic leukemia escape repertoire to generate immune suppression: impact of the HLA-G 14 base pair (rs66554220) polymorphism.

Published by

Haematologica

Summary

journal-article

Detection of TP53 dysfunction in chronic lymphocytic leukemia by an in vitro functional assay based on TP53 activation by the non-genotoxic drug Nutlin-3: a proposal for clinical application.

Published by

Journal of hematology & oncology

Summary

journal-article

Endothelium-mediated survival of leukemic cells and angiogenesis-related factors are affected by lenalidomide treatment in chronic lymphocytic leukemia.

Published by

Experimental hematology

Summary

journal-article

Outcome prediction of diffuse large B-cell lymphomas associated with hepatitis C virus infection: a study on behalf of the Fondazione Italiana Linfomi.

Published by

Haematologica

Summary

journal-article

CD49d is overexpressed by trisomy 12 chronic lymphocytic leukemia cells: evidence for a methylation-dependent regulation mechanism.

Published by

Blood

Summary

journal-article

Clinical monoclonal B lymphocytosis versus Rai 0 chronic lymphocytic leukemia: A comparison of cellular, cytogenetic, molecular, and clinical features.

Published by

Clinical cancer research : an official journal of the American Association for Cancer Research

Summary

journal-article

Molecular bases of chronic lymphocytic leukemia in light of new treatments.

Published by

Immunology letters

Summary

journal-article

Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome.

Published by

Blood

Summary

journal-article

Pomalidomide, cyclophosphamide, and prednisone for relapsed/refractory multiple myeloma: a multicenter phase 1/2 open-label study.

Published by

Blood

Summary

journal-article

Promoter methylation patterns in Richter syndrome affect stem-cell maintenance and cell cycle regulation and differ from de novo diffuse large B-cell lymphoma.

Published by

British journal of haematology

Summary

journal-article

Inherited susceptibility to chronic lymphocytic leukemia: the good candidates.

Published by

Leukemia & lymphoma

Summary

journal-article

IX. Chronic lymphocytic leukaemia: new genetic markers as prognostic factors.

Published by

Hematological oncology

Summary

journal-article

Association between molecular lesions and specific B-cell receptor subsets in chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

Clinical implications of the molecular genetics of chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

Genetic aberrations of signaling pathways in lymphomagenesis: revelations from next generation sequencing studies.

Published by

Seminars in cancer biology

Summary

journal-article

rs2072135, a low-penetrance variant for chronic lymphocytic leukaemia?

Published by

British journal of haematology

Summary

journal-article

Clues to pathogenesis of Waldenström macroglobulinemia and immunoglobulin M monoclonal gammopathy of undetermined significance provided by analysis of immunoglobulin heavy chain gene rearrangement and clustering of B-cell receptors.

Published by

Leukemia & lymphoma

Summary

journal-article

ARHGDIA, a mutant TP53-associated Rho GDP dissociation inhibitor, is over-expressed in gene expression profiles of TP53 disrupted chronic lymphocytic leukaemia cells.

Published by

British journal of haematology

Summary

journal-article

Age and organ damage correlate with poor survival in myeloma patients: meta-analysis of 1435 individual patient data from 4 randomized trials.

Published by

Haematologica

Summary

journal-article

MYC addiction in chronic lymphocytic leukemia.

Published by

Leukemia & lymphoma

Summary

journal-article

Richter syndrome.

Published by

Advances in experimental medicine and biology

Summary

journal-article

The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

Cardiovascular events and intensity of treatment in polycythemia vera.

Published by

The New England journal of medicine

Summary

journal-article

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

Molecular genetics of high-risk chronic lymphocytic leukemia.

Published by

Expert review of hematology

Summary

journal-article

Clinical significance of c.7544-7545 delCT NOTCH1 mutation in chronic lymphocytic leukaemia.

Published by

British journal of haematology

Summary

journal-article

MGA, a suppressor of MYC, is recurrently inactivated in high risk chronic lymphocytic leukemia.

Published by

Leukemia & lymphoma

Summary

journal-article

The spectrum of genetic defects in chronic lymphocytic leukemia.

Published by

Mediterranean journal of hematology and infectious diseases

Summary

journal-article

Clinical heterogeneity of de novo 11q deletion chronic lymphocytic leukaemia: prognostic relevance of extent of 11q deleted nuclei inside leukemic clone.

Published by

Hematological oncology

Summary

journal-article

Richter syndrome and fludarabine: a controversial relationship.

Published by

Leukemia & lymphoma

Summary

journal-article

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.

Published by

The Journal of experimental medicine

Summary

journal-article

Different impact of NOTCH1 and SF3B1 mutations on the risk of chronic lymphocytic leukemia transformation to Richter syndrome.

Published by

British journal of haematology

Summary

journal-article

Nuclear factor-κB dysregulation in splenic marginal zone lymphoma: new therapeutic opportunities.

Published by

Haematologica

Summary

journal-article

Extra-osseous Ewing sarcoma of the thyroid gland mimicking lymphoma recurrence: a case report.

Published by

Pathology, research and practice

Summary

journal-article

Analysis of SF3B1 mutations in monoclonal B-cell lymphocytosis.

Published by

Hematological oncology

Summary

journal-article

Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

ATM and chronic lymphocytic leukemia: mutations, and not only deletions, matter.

Published by

Haematologica

Summary

journal-article

IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia.

Published by

Journal of translational medicine

Summary

journal-article

The IGHV1-69/IGHJ3 recombinations of unmutated CLL are distinct from those of normal B cells.

Published by

Blood

Summary

journal-article

Absence of NOTCH1 gene mutations in MALT lymphomas.

Published by

British journal of haematology

Summary

journal-article

Multiple myeloma shows no intra-disease clustering of immunoglobulin heavy chain genes.

Published by

Haematologica

Summary

journal-article

NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL.

Published by

Haematologica

Summary

journal-article

Integrated DNA copy number and methylation profiling of lymphoid neoplasms using a single array.

Published by

British journal of haematology

Summary

journal-article

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

Analysis of NOTCH1 mutations in monoclonal B-cell lymphocytosis.

Published by

Haematologica

Summary

journal-article

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death.

Published by

Blood

Summary

journal-article

Hepatitis B virus and lymphomagenesis: novel insights into an occult relationship.

Published by

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Summary

journal-article

Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness.

Published by

Blood

Summary

journal-article

Safety and efficacy of bortezomib-melphalan-prednisone-thalidomide followed by bortezomib-thalidomide maintenance (VMPT-VT) versus bortezomib-melphalan-prednisone (VMP) in untreated multiple myeloma patients with renal impairment.

Published by

Blood

Summary

journal-article

The coexistence of chronic lymphocytic leukemia and myeloproliperative neoplasms: a retrospective multicentric GIMEMA experience.

Published by

American journal of hematology

Summary

journal-article

Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma.

Published by

Blood

Summary

journal-article

Extramedullary intracranial localization of multiple myeloma and treatment with novel agents: a retrospective survey of 50 patients.

Published by

Cancer

Summary

journal-article

Molecular history of Richter syndrome: origin from a cell already present at the time of chronic lymphocytic leukemia diagnosis.

Published by

International journal of cancer

Summary

journal-article

Analysis of the coding genome of diffuse large B-cell lymphoma.

Published by

Nature genetics

Summary

journal-article

Genome-wide DNA profiling better defines the prognosis of chronic lymphocytic leukaemia.

Published by

British journal of haematology

Summary

journal-article

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.

Published by

The Journal of experimental medicine

Summary

journal-article

Association between single nucleotide polymorphism-genotype and outcome of patients with chronic lymphocytic leukemia in a randomized chemotherapy trial.

Published by

Haematologica

Summary

journal-article

Del(13q14.3) length matters: an integrated analysis of genomic, fluorescence in situ hybridization and clinical data in 169 chronic lymphocytic leukaemia patients with 13q deletion alone or a normal karyotype.

Published by

Hematological oncology

Summary

journal-article

Saliva is a reliable and practical source of germline DNA for genome-wide studies in chronic lymphocytic leukemia.

Published by

Leukemia research

Summary

journal-article

13q14 deletion size and number of deleted cells both influence prognosis in chronic lymphocytic leukemia.

Published by

Genes, chromosomes & cancer

Summary

journal-article

Common genetic variation at 15q25.2 impacts on chronic lymphocytic leukaemia risk.

Published by

British journal of haematology

Summary

journal-article

Lenalidomide can induce long-term responses in patients with multiple myeloma relapsing after multiple chemotherapy lines, in particular after allogeneic transplant.

Published by

Leukemia & lymphoma

Summary

journal-article

Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network.

Published by

Cancer research

Summary

journal-article

In vitro efficacy of tyrosine kinase inhibitors: SYK and BCR-ABL inhibitors in lymphomas.

Published by

Hematological oncology

Summary

journal-article

Inactivating mutations of acetyltransferase genes in B-cell lymphoma.

Published by

Nature

Summary

journal-article

Predictive markers and driving factors behind Richter syndrome development.

Published by

Expert review of anticancer therapy

Summary

journal-article

B-cell receptor, clinical course and prognosis in chronic lymphocytic leukaemia: the growing saga of the IGHV3 subgroup gene usage.

Published by

British journal of haematology

Summary

journal-article

Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trial.

Published by

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Summary

journal-article

Complete response correlates with long-term progression-free and overall survival in elderly myeloma treated with novel agents: analysis of 1175 patients.

Published by

Blood

Summary

journal-article

The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation.

Published by

Blood

Summary

journal-article

Tracking the biological risk of coronary artery disease in HIV-infected individuals: the case of circulating endothelial progenitor cells.

Published by

AIDS (London, England)

Summary

journal-article

A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome.

Published by

British journal of haematology

Summary

journal-article

Biological and clinical significance of stereotyped B-cell receptors in chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

The host genetic background of DNA repair mechanisms is an independent predictor of survival in diffuse large B-cell lymphoma.

Published by

Blood

Summary

journal-article

Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: a randomized controlled trial.

Published by

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Summary

journal-article

Free light-chains and renal disorders: when small is worse.

Published by

Lancet (London, England)

Summary

journal-article

BCL3 translocation in CLL with typical phenotype: assessment of frequency, association with cytogenetic subgroups, and prognostic significance.

Published by

British journal of haematology

Summary

journal-article

Inherited genetic susceptibility to monoclonal B-cell lymphocytosis.

Published by

Blood

Summary

journal-article

Efficacy and safety of once-weekly bortezomib in multiple myeloma patients.

Published by

Blood

Summary

journal-article

Low CD49d expression and long telomere identify a chronic lymphocytic leukemia subset with highly favourable outcome.

Published by

American journal of hematology

Summary

journal-article

Analysis of the REL, BCL11A, and MYCN proto-oncogenes belonging to the 2p amplicon in chronic lymphocytic leukemia.

Published by

American journal of hematology

Summary

journal-article

Multicentre validation of a prognostic index for overall survival in chronic lymphocytic leukaemia.

Published by

Hematological oncology

Summary

journal-article

Genomic profiling of Richter's syndrome: recurrent lesions and differences with de novo diffuse large B-cell lymphomas.

Published by

Hematological oncology

Summary

journal-article

Beta-2-microglobulin is an independent predictor of progression in asymptomatic multiple myeloma.

Published by

Cancer

Summary

journal-article

Renal outcome and monoclonal immunoglobulin deposition disease in 289 old patients with blood cell dyscrasias: a single center experience.

Published by

Critical reviews in oncology/hematology

Summary

journal-article

Stereotyped patterns of B-cell receptor in splenic marginal zone lymphoma.

Published by

Haematologica

Summary

journal-article

Angiopoietin-2 plasma dosage predicts time to first treatment and overall survival in chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells.

Published by

Journal of translational medicine

Summary

journal-article

Single nucleotide polymorphism-arrays provide new insights in the pathogenesis of post-transplant diffuse large B-cell lymphoma.

Published by

British journal of haematology

Summary

journal-article

Impact of the host genetic background on prognosis of chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

Derivative (1)t(1;16)(p11;p11.1) in myelodysplastic syndrome: a case report and review of the literature.

Published by

Cancer genetics and cytogenetics

Summary

journal-article

Expression of mutated IGHV3-23 genes in chronic lymphocytic leukemia identifies a disease subset with peculiar clinical and biological features.

Published by

Clinical cancer research : an official journal of the American Association for Cancer Research

Summary

journal-article

Melphalan, prednisone, thalidomide and defibrotide in relapsed/refractory multiple myeloma: results of a multicenter phase I/II trial.

Published by

Haematologica

Summary

journal-article

Genome wide DNA-profiling of HIV-related B-cell lymphomas.

Published by

British journal of haematology

Summary

journal-article

Monitoring of cytomegalovirus reactivation during induction and nontransplant consolidation of acute leukemia.

Published by

American journal of hematology

Summary

journal-article

Molecular characterization of post-transplant lymphoproliferative disorders of donor origin occurring in liver transplant recipients.

Published by

The Journal of pathology

Summary

journal-article

Proposal and validation of prognostic scoring systems for IgG and IgA monoclonal gammopathies of undetermined significance.

Published by

Clinical cancer research : an official journal of the American Association for Cancer Research

Summary

journal-article

Stereotyped B-cell receptor is an independent risk factor of chronic lymphocytic leukemia transformation to Richter syndrome.

Published by

Clinical cancer research : an official journal of the American Association for Cancer Research

Summary

journal-article

The prognosis of clinical monoclonal B cell lymphocytosis differs from prognosis of Rai 0 chronic lymphocytic leukaemia and is recapitulated by biological risk factors.

Published by

British journal of haematology

Summary

journal-article

CD38/CD31, the CCL3 and CCL4 chemokines, and CD49d/vascular cell adhesion molecule-1 are interchained by sequential events sustaining chronic lymphocytic leukemia cell survival.

Published by

Cancer research

Summary

journal-article

Occult hepatitis B virus infection of peripheral blood mononuclear cells among treatment-naive patients with chronic lymphocytic leukemia.

Published by

Leukemia & lymphoma

Summary

journal-article

Richter syndrome: molecular insights and clinical perspectives.

Published by

Hematological oncology

Summary

journal-article

The NF-{kappa}B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas.

Published by

Blood

Summary

journal-article

The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of Del17p13: implications for overall survival and chemorefractoriness.

Published by

Clinical cancer research : an official journal of the American Association for Cancer Research

Summary

journal-article

IGHD3-3 fails to behave as unfavourable prognostic marker in chronic lymphocytic leukaemia.

Published by

British journal of haematology

Summary

journal-article

Thyroid lymphoma: beyond antigen stimulation.

Published by

Leukemia research

Summary

journal-article

Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study.

Published by

British journal of haematology

Summary

journal-article

14q32 Translocations and risk of Richter transformation in chronic lymphocytic leukaemia.

Published by

British journal of haematology

Summary

journal-article

Genome-wide DNA analysis identifies recurrent imbalances predicting outcome in chronic lymphocytic leukaemia with 17p deletion.

Published by

British journal of haematology

Summary

journal-article

CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia.

Published by

Haematologica

Summary

journal-article

Molecular analysis of immunoglobulin variable genes in human immunodeficiency virus-related non-Hodgkin's lymphoma reveals implications for disease pathogenesis and histogenesis.

Published by

Haematologica

Summary

journal-article

Biological and clinical risk factors of chronic lymphocytic leukaemia transformation to Richter syndrome.

Published by

British journal of haematology

Summary

journal-article

CD38 gene polymorphism and chronic lymphocytic leukemia: a role in transformation to Richter syndrome?

Published by

Blood

Summary

journal-article

Early stage chronic lymphocytic leukaemia carrying unmutated IGHV genes is at risk of recurrent infections during watch and wait.

Published by

British journal of haematology

Summary

journal-article

High density genome-wide DNA profiling reveals a remarkably stable profile in hairy cell leukaemia.

Published by

British journal of haematology

Summary

journal-article

Selective influences in the expressed immunoglobulin heavy and light chain gene repertoire in hairy cell leukemia.

Published by

Haematologica

Summary

journal-article

Epigenetic inactivation of suppressors of cytokine signalling in Philadelphia-negative chronic myeloproliferative disorders.

Published by

British journal of haematology

Summary

journal-article

Prognostic assessment of BCL2-938C>A polymorphism in chronic lymphocytic leukemia.

Published by

Blood

Summary

journal-article

Transient monoclonal expansion of CD8+/CD57+ T-cell large granular lymphocytes after primary cytomegalovirus infection.

Published by

American journal of hematology

Summary

journal-article

Bone marrow necrosis complicating post-transplant lymphoproliferative disorder: resolution with rituximab.

Published by

Leukemia research

Summary

journal-article

JAK2V617F in idiopathic venous thromboembolism occurring in the absence of inherited or acquired thrombophilia.

Published by

British journal of haematology

Summary

journal-article

Prevalence and clinical characteristics of immune thrombocytopenic purpura in a cohort of monoclonal gammopathy of uncertain significance.

Published by

British journal of haematology

Summary

journal-article

Analysis of immunoglobulin heavy and light chain variable genes in post-transplant lymphoproliferative disorders.

Published by

Hematological oncology

Summary

journal-article

Simultaneous diagnosis of CD3+ T-cell large granular lymphocyte leukaemia and true thymic hyperplasia.

Published by

Leukemia research

Summary

journal-article

Aberrant somatic hypermutation in transformation of follicular lymphoma and chronic lymphocytic leukemia to diffuse large B-cell lymphoma.

Published by

Haematologica

Summary

journal-article

B-cell posttransplant lymphoproliferative disorders in heart and/or lungs recipients: clinical and molecular-histogenetic study of 17 cases from a single institution.

Published by

Transplantation

Summary

journal-article

Hairy cell leukaemia complicated by anti-MAG paraproteinemic demyelinating neuropathy: resolution of neurological syndrome after cladribrine treatment.

Published by

Leukemia research

Summary

journal-article

JAK2 V617F mutation in leukaemic transformation of philadelphia-negative chronic myeloproliferative disorders.

Published by

British journal of haematology

Summary

journal-article

Comparative genome-wide profiling of post-transplant lymphoproliferative disorders and diffuse large B-cell lymphomas.

Published by

British journal of haematology

Summary

journal-article

Usefulness of JAK2V617F mutation in distinguishing idiopathic erythrocytosis from polycythemia vera.

Published by

Leukemia research

Summary

journal-article

Downregulation of the major histocompatibility complex class I molecules by human herpesvirus type 8 and impaired natural killer cell activity in primary effusion lymphoma development.

Published by

British journal of haematology

Summary

journal-article

Post-transplant lymphoproliferative disorders: molecular basis of disease histogenesis and pathogenesis.

Published by

Hematological oncology

Summary

journal-article

Aberrant somatic hypermutation in post-transplant lymphoproliferative disorders.

Published by

British journal of haematology

Summary

journal-article

POEMS and calciphylaxis: a novel association?

Published by

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna

Summary

journal-article

Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas.

Published by

British journal of haematology

Summary

journal-article

Incidence of novel N-glycosylation sites in the B-cell receptor of lymphomas associated with immunodeficiency.

Published by

British journal of haematology

Summary

journal-article

Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia.

Published by

Haematologica

Summary

journal-article

CCL19 and CXCL12 trigger in vitro chemotaxis of human mantle cell lymphoma B cells.

Published by

Clinical cancer research : an official journal of the American Association for Cancer Research

Summary

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Frequent aberrant promoter hypermethylation of O6-methylguanine-DNA methyltransferase and death-associated protein kinase genes in immunodeficiency-related lymphomas.

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British journal of haematology

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Molecular histogenesis of posttransplantation lymphoproliferative disorders.

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Blood

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Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma.

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Blood

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Messengers of cell death: apoptotic signaling in health and disease.

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Haematologica

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Simian virus 40 infection in lymphoproliferative disorders.

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Lancet (London, England)

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Molecular histogenesis of plasmablastic lymphoma of the oral cavity.

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British journal of haematology

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Primary cutaneous large B-cell lymphoma of the leg: histogenetic analysis of a controversial clinicopathologic entity.

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Human pathology

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Molecular heterogeneity of diffuse large B-cell lymphoma: implications for disease management and prognosis.

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Hematology (Amsterdam, Netherlands)

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Alternative translocation breakpoint cluster region 5' to BCL-6 in B-cell non-Hodgkin's lymphoma.

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Cancer research

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Anaplastic large cell lymphoma and acquired angioedema: a novel association?

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Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna

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Human herpesvirus type 8-associated primary lymphomatous effusion in an elderly HIV-negative patient: clinical and molecular characterization.

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Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna

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Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma.

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Journal of the National Cancer Institute

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