F. Jeffrey Dilworth

Work

University of Wisconsin-Madison
|

Professor

US

Ottawa Hospital Research Institute
|

Senior Scientist

Canada

Education

Queen's University
Canada

PhD

Publications

SMCHD1 activates the expression of genes required for the expansion of human myoblasts

Published by

Nucleic Acids Research

Summary

journal-article

Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating Jmjd3.

Published by

eLife

Summary

journal-article

Progeria-based vascular model identifies networks associated with cardiovascular aging and disease.

Published by

Aging cell

Summary

journal-article

Epigenetic integration of signaling from the regenerative environment.

Published by

Current topics in developmental biology

Summary

journal-article

SMCHD1 activates the expression of genes required for the expansion of human myoblasts

Summary

preprint

Epigenetic control of myogenic identity of human muscle stem cells in Duchenne Muscular Dystrophy

Summary

preprint

JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment.

Published by

Science (New York, N.Y.)

Summary

journal-article

The Hunt Is On! In Pursuit of the Ideal Stem Cell Population for Cartilage Regeneration.

Published by

Frontiers in bioengineering and biotechnology

Summary

journal-article

Chromatin Reorganization during Myoblast Differentiation Involves the Caspase-Dependent Removal of SATB2.

Published by

Cells

Summary

journal-article

Chromatin and transcription factor profiling in rare stem cell populations using CUT&Tag.

Published by

STAR protocols

Summary

journal-article

The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.

Published by

Nucleic acids research

Summary

journal-article

HIRA stabilizes skeletal muscle lineage identity

Published by

Nature Communications

Summary

journal-article

Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation.

Published by

Developmental cell

Summary

journal-article

Epigenetic regulation of satellite cell fate during skeletal muscle regeneration.

Published by

Skeletal muscle

Summary

journal-article

Derivation and Characterization of Immortalized Human Muscle Satellite Cell Clones from Muscular Dystrophy Patients and Healthy Individuals

Published by

Cells

Summary

journal-article

Derivation and Characterization of Immortalized Human Muscle Satellite Cell Clones from Muscular Dystrophy Patients and Healthy Individuals

Published by

Cells

Summary

journal-article

Intron Retained, Transcript Detained: Intron Retention as a Hallmark of the Quiescent Satellite Cell State.

Published by

Developmental cell

Summary

journal-article

Dysregulated expression of monoacylglycerol lipase is a marker for anti-diabetic drug metformin-targeted therapy to correct impaired neurogenesis and spatial memory in Alzheimer's disease.

Published by

Theranostics

Summary

journal-article

The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance

Published by

Oncogene

Summary

journal-article

Tendon contains more stem cells than bone at the rotator cuff repair site.

Published by

Journal of shoulder and elbow surgery

Summary

journal-article

Polycomb/Trithorax Antagonism: Cellular Memory in Stem Cell Fate and Function.

Published by

Cell stem cell

Summary

journal-article

Diversification of the muscle proteome through alternative splicing

Published by

Skeletal Muscle

Summary

journal-article

Targeting the MTF2-MDM2 Axis Sensitizes Refractory Acute Myeloid Leukemia to Chemotherapy.

Published by

Cancer discovery

Summary

journal-article

Epigenetic Regulation of Adult Myogenesis.

Published by

Current topics in developmental biology

Summary

journal-article

Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice

Published by

Molecular Biology of the Cell

Summary

journal-article

Polycomb repressive complex 1 provides a molecular explanation for repeat copy number dependency in FSHD muscular dystrophy

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Human Molecular Genetics

Summary

journal-article

Reprogramming progeria fibroblasts re-establishes a normal epigenetic landscape

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Aging Cell

Summary

journal-article

Splicing of Ezh1 gets muscle out of stressful situations

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Nature Structural and Molecular Biology

Summary

journal-article

Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation

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Skeletal Muscle

Summary

journal-article

Compacting Chromatin to Ensure Muscle Satellite Cell Quiescence

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Cell Stem Cell

Summary

journal-article

Temporal activation of XRCC1-mediated DNA repair is essential for muscle differentiation

Published by

Cell Discovery

Summary

journal-article

UTX demethylase activity is required for satellite cell-mediated muscle regeneration

Published by

Journal of Clinical Investigation

Summary

journal-article

UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia

Published by

Genes and Development

Summary

journal-article

A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation

Published by

Genes and Development

Summary

journal-article

Noncoding RNAs as epigenetic mediators of skeletal muscle regeneration

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FEBS Journal

Summary

journal-article

Nuclear matrix-associated protein SMAR1 regulates alternative splicing via HDAC6-mediated deacetylation of Sam68

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Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Rbfox proteins regulate tissue-specific alternative splicing of Mef2D required for muscle differentiation

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Journal of Cell Science

Summary

journal-article

Dystrophic muscle environment induces changes in cell plasticity

Published by

Genes and Development

Summary

journal-article

Trichostatin a enhances vascular repair by injected human endothelial progenitors through increasing the expression of TAL1-dependent genes

Published by

Cell Stem Cell

Summary

journal-article

Chaperoning RNA Polymerase II through repressive chromatin

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EMBO Journal

Summary

journal-article

Differential modulation of cell cycle progression distinguishes members of the myogenic regulatory factor family of transcription factors

Published by

FEBS Journal

Summary

journal-article

Six1 Regulates MyoD Expression in Adult Muscle Progenitor Cells

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PLoS ONE

Summary

journal-article

Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation

Published by

Genes and Development

Summary

journal-article

Comparative expression profiling identifies differential roles for Myogenin and p38α MAPK signaling in myogenesis

Published by

Journal of Molecular Cell Biology

Summary

journal-article

GSK3 temporally regulates Neurogenin 2 proneural activity in the neocortex

Published by

Journal of Neuroscience

Summary

journal-article

Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A

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Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Modulation of Developmentally Regulated Gene Expression Programs through Targeting of Polycomb and Trithorax Group Proteins

Published by

Toxicology and Epigenetics

Summary

book

Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex

Published by

EMBO Journal

Summary

journal-article

The Origin and Fate of Muscle Satellite Cells

Published by

Stem Cell Reviews and Reports

Summary

journal-article

Turning on myogenin in muscle: A paradigm for understanding mechanisms of tissue-specific gene expression

Published by

Comparative and Functional Genomics

Summary

journal-article

Constitutive heterochromatin reorganization during somatic cell reprogramming

Published by

EMBO Journal

Summary

journal-article

Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages

Published by

EMBO Journal

Summary

journal-article

Epigenetic regulation of satellite cell activation during muscle regeneration

Published by

Stem Cell Research and Therapy

Summary

journal-article

Redirecting traffic in the nucleus

Published by

Developmental Cell

Summary

journal-article

Teashirt-3, a novel regulator of muscle differentiation, associates with BRG1-associated factor 57 (BAF57) to inhibit myogenin gene expression

Published by

Journal of Biological Chemistry

Summary

journal-article

Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks

Published by

Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Regulating a master regulator: Establishing tissue-specific gene expression in skeletal muscle

Published by

Epigenetics

Summary

journal-article

UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

Published by

EMBO Journal

Summary

journal-article

Dual role for the methyltransferase G9a in the maintenance of β-globin gene transcription in adult erythroid cells

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Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state

Published by

Genes and Development

Summary

journal-article

Analysis of epigenetic modifications of chromatin at specific gene loci by native chromatin immunoprecipitation of nucleosomes isolated using hydroxyapatite chromatography

Published by

Nature Protocols

Summary

journal-article

Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex

Published by

Nature Cell Biology

Summary

journal-article

Activator-Mediated Recruitment of the MLL2 Methyltransferase Complex to the β-Globin Locus

Published by

Molecular Cell

Summary

journal-article

p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation

Published by

Nature Structural and Molecular Biology

Summary

journal-article

The RNA Helicases p68/p72 and the Noncoding RNA SRA Are Coregulators of MyoD and Skeletal Muscle Differentiation

Published by

Developmental Cell

Summary

journal-article

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator

Published by

Molecular Cell

Summary

journal-article

A MyoD -generated feed-forward circuit temporally patterns gene expression dining skeletal muscle differentiation

Published by

Genes and Development

Summary

journal-article

In vitro transcription system delineates the distinct roles of the coactivators pCAF and p300 during MyoD/E47-dependent transactivation

Published by

Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription

Published by

Oncogene

Summary

journal-article

The novel transcription factor e(y)2 interacts with TAFII40 and potentiates transcription activation on chromatin templates

Published by

Molecular and Cellular Biology

Summary

journal-article

UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation

Published by

EMBO Journal

Summary

journal-article

ATP-driven chromatin remodeling activity and histone acetyltransferase act sequentially during transactivation by RAR/RXR in vitro

Published by

Molecular Cell

Summary

journal-article

Contribution of several metabolites of the vitamin D analog 20-epi-22-oxa-24a,26a,27a-tri-homo-1,25-(OH)2 vitamin D3 (KH 1060) to the overall biological activity of KH1060 by a shared mechanism of action

Published by

Biochemical Pharmacology

Summary

journal-article

Ligand-dependent activation of transcription in vitro by retinoic acid receptor α/retinoid X receptor α heterodimers that mimics transactivation by retinoids in vivo

Published by

Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Erratum: Metabolism of the vitamin D analog EB1089 by cultured human cells: Redirection of hydroxylation site to distal carbons of the side-chain (Biochemical Pharmacology (1997) 53 (773-782))

Published by

Biochemical Pharmacology

Summary

journal-article

Metabolism of the vitamin D analog EB1089 by cultured human cells: Redirection of hydroxylation site to distal carbons of the side-chain

Published by

Biochemical Pharmacology

Summary

journal-article

The vitamin D analog, KH1060, is rapidly degraded both in vivo and in vitro via several pathways: Principal metabolites generated retain significant biological activity

Published by

Endocrinology

Summary

journal-article

cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes p450 (CYP26)

Published by

Journal of Biological Chemistry

Summary

journal-article

Construction of a P450c27 fusion enzyme: A useful tool for analysis of vitamin D3 25-hydroxylase activity

Published by

Biochemical Journal

Summary

journal-article

Identification of the retinoic acid-inducible all-trans-retinoic acid 4- hydroxylase

Published by

Journal of Biological Chemistry

Summary

journal-article

Different mechanisms of hydroxylation site selection by liver and kidney cytochrome P450 species (CYP27 and CYP24) involved in vitamin D metabolism

Published by

Journal of Biological Chemistry

Summary

journal-article

Increased biological activity of 20-EPI-1,25-dihydroxyvitamin D<inf>3</inf> is due to reduced catabolism and altered protein binding

Published by

Biochemical Pharmacology

Summary

journal-article