Evaluation of hippocampal DLGAP2 overexpression on cognition, synaptic function, and dendritic spine structure in a translationally relevant AD mouse model
Summary
preprint
An in vitro neurogenetics platform for precision disease modeling in the mouse
Published by
Science Advances
Summary
journal-article
RNA Strain-Match: A tool for matching single-nucleus, single-cell, or bulk RNA-sequencing alignment data to its corresponding genotype
Summary
preprint
Detecting the effect of genetic diversity on brain composition in an Alzheimer’s disease mouse model
Summary
preprint
High sucrose consumption decouples intrinsic and synaptic excitability of AgRP neurons without altering body weight
Published by
International Journal of Obesity
Summary
journal-article
High Sucrose consumption decouples intrinsic and synaptic excitability of AgRP neurons without altering body weight
Summary
preprint
Hypothalamic gene network dysfunction is associated with cognitive decline and body weight loss in Alzheimer’s disease mice
Summary
preprint
Life-long Dietary Restrictions have Negligible or Damaging Effects on Late-life Cognitive Performance: A Key Role for Genetics in Outcomes
Summary
preprint
Anin vitroneurogenetics platform for precision disease modeling in the mouse
Summary
preprint
High-fat diet induced loss of GABAergic inhibition decouples intrinsic and synaptic excitability in AgRP neurons
Summary
other
Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice
Published by
Learning & Memory
Summary
journal-article
Genetic background modifies CNS‐mediated sensorimotor decline in the AD‐BXD mouse model of genetic diversity in Alzheimer's disease
Published by
Genes, Brain and Behavior
Summary
journal-article
Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse population
Summary
other
Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine.
Published by
Neuron
Summary
journal-article
Cell-Type-Specific Changes in Intrinsic Excitability in the Subiculum following Learning and Exposure to Novel Environmental Contexts.
Published by
eNeuro
Summary
journal-article
Human dental stem cell derived transgene-free iPSCs generate functional neurons via embryoid body-mediated and direct induction methods.
Published by
Journal of tissue engineering and regenerative medicine
Summary
journal-article
Diet composition, not calorie intake, rapidly alters intrinsic excitability of hypothalamic AgRP/NPY neurons in mice.
Published by
Scientific reports
Summary
journal-article
Leptin Modulates the Intrinsic Excitability of AgRP/NPY Neurons in the Arcuate Nucleus of the Hypothalamus
Published by
Journal of Neuroscience
Summary
journal-article
The C-terminus of neuronal Kv2.1 channels is required for channel localization and targeting but not for NMDA-receptor-mediated regulation of channel function.
Summary
journal-article
Localization-dependent activity of the Kv2.1 delayed-rectifier K+ channel
Published by
Proceedings of the National Academy of Sciences
Summary
journal-article
Localization and mobility of the delayed-rectifer K+ channel Kv2.1 in adult cardiomyocytes
Published by
AJP: Heart and Circulatory Physiology
Summary
journal-article
A cytoskeletal-based perimeter fence selectively corrals a sub-population of cell surface Kv2.1 channels
Published by
Journal of Cell Science
Summary
journal-article
Kv2.1 potassium channels are retained within dynamic cell surface microdomains that are defined by a perimeter fence.
Summary
journal-article
Targeting of voltage-gated potassium channel isoforms to distinct cell surface microdomains.
Summary
journal-article
Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling.
Summary
journal-article
Localization of ion channels to lipid Raft domains within the cardiovascular system.
Summary
journal-article
Targeting of ion channels to membrane microdomains: localization of KV channels to lipid rafts
Published by
Trends in Pharmacological Sciences
Summary
journal-article
Suramin interacts with the calmodulin binding site on the ryanodine receptor, RYR1.
Summary
journal-article
Calmodulin binding to the 3614-3643 region of RyR1 is not essential for excitation-contraction coupling in skeletal myotubes.