Manuel Augusto Llanos

Work

Scripps Research Institute
|

Postdoctoral Research Associate

US

National University of La Plata
|

Teaching Assistant

Argentina

Education

National University of La Plata
Argentina

PhD

National University of La Plata
Argentina

Pharmacist

Publications

Meeko: molecule parameterization and software interoperability for docking and beyond

Summary

preprint

Structure-based rational design of covalent probes

Published by

Communications Chemistry

Summary

journal-article

Discovery of Trypanosoma cruzi Carbonic Anhydrase Inhibitors by a Combination of Ligand- and Structure-Based Virtual Screening

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

An mRNA Display Approach for Covalent Targeting of a <i>Staphylococcus aureus</i> Virulence Factor

Published by

Journal of the American Chemical Society

Summary

journal-article

CosolvKit: a Versatile Tool for Cosolvent MD Preparation and Analysis

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

CosolvKit: a versatile tool for cosolvent MD preparation and analysis

Summary

preprint

CosolvKit: a versatile tool for cosolvent MD preparation and analysis

Summary

preprint

In Silico Screening Identification of Fatty Acids and Fatty Acid Derivatives with Antiseizure Activity: In Vitro and In Vivo Validation

Published by

Pharmaceutics

Summary

journal-article

A Combined Ligand- and Structure-Based Virtual Screening To Identify Novel NaV1.2 Blockers: In Vitro Patch Clamp Validation and In Vivo Anticonvulsant Activity

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro

Published by

Frontiers in Pharmacology

Summary

journal-article

A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity

Published by

Journal of Computer-Aided Molecular Design

Summary

journal-article

LIDeB Tools: a Latin American resource of freely available, open-source cheminformatics apps

Published by

Artificial Intelligence in the Life Sciences

Summary

journal-article

Identification of New Carbonic Anhydrase VII Inhibitors by Structure-Based Virtual Screening

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

Descubrimiento de nuevos anticonvulsivos que actúan mediante interacciones con canales iónicos

Summary

dissertation-thesis

Novel Dimeric hHv1 Model and Structural Bioinformatic Analysis Reveal an ATP-Binding Site Resulting in a Channel Activating Effect

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

iRaPCA and SOMoC: Development and Validation of Web Applications for New Approaches for the Clustering of Small Molecules

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

Structure-Based Virtual Screening Identifies Novobiocin, Montelukast, and Cinnarizine as TRPV1 Modulators with Anticonvulsant Activity <i>In Vivo</i>

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

Structure-Based Virtual Screening Identifies Novobiocin, Montelukast, and Cinnarizine as TRPV1 Modulators with Anticonvulsant Activity <i>In Vivo</i>

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

Structure-Based Virtual Screening Identifies Novobiocin, Montelukast, and Cinnarizine as TRPV1 Modulators with Anticonvulsant Activity <i>In Vivo</i>

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

Structure-Based Virtual Screening Identifies Novobiocin, Montelukast, and Cinnarizine as TRPV1 Modulators with Anticonvulsant Activity <i>In Vivo</i>

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

Homology Modeling and Molecular Dynamics Simulations of Trypanosoma cruzi Phosphodiesterase b1

Published by

Chemistry & Biodiversity

Summary

journal-article

Computational and Synthetic Target-based Approaches to the Discovery of Novel Anticonvulsant Compounds

Published by

Current Medicinal Chemistry

Summary

journal-article

Strengths and Weaknesses of Docking Simulations in the SARS-CoV-2 Era: the Main Protease (Mpro) Case Study

Published by

Journal of Chemical Information and Modeling

Summary

journal-article

Can drug repurposing strategies be the solution to the COVID-19 crisis?

Published by

Expert Opinion on Drug Discovery

Summary

journal-article

Point mutations affecting yeast prion propagation change the structure of its amyloid fibrils

Published by

Journal of Molecular Liquids

Summary

journal-article

Citrus reticulata peel oil as an antiatherogenic agent: Hypolipogenic effect in hepatic cells, lipid storage decrease in foam cells, and prevention of LDL oxidation

Published by

Nutrition, Metabolism and Cardiovascular Diseases

Summary

journal-article

A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors

Published by

Journal of Enzyme Inhibition and Medicinal Chemistry

Summary

journal-article