Naoya Yahagi

Detection Method for Gene Doping in a Mouse Model Expressing Human Erythropoietin from Adeno-Associated Virus Vector-9

working-paper

Community-based HbA1c testing programme for early detection of undiagnosed diabetes in community pharmacy

International Journal of Pharmacy Practice

Jan 2025

journal-article

Evaluation of the Effectiveness of Feedback in a Remote Monitoring Home-Based Training System for Workers: A Medium-Scale Randomized Parallel-Group Controlled Trial

Healthcare

Jan 2025

journal-article

Evaluation of the Effectiveness of Feedback in a Remote Monitoring Home-Based Training System for Workers: A Medium-Scale Randomized Parallel-Group Controlled Trial

Healthcare

Jan 2025

journal-article

Detection Method for Gene Doping in a Mouse Model Expressing Human Erythropoietin from Adeno-Associated Virus Vector-9

Genes

Jan 2024

journal-article

Detection Method for Gene Doping in a Mouse Model Expressing Human Erythropoietin from Adeno-Associated Virus Vector-9

Genes

Jan 2024

journal-article

Detection Method for Gene Doping in a Mouse Model Expressing Human Erythropoietin from Adeno-Associated Virus Vector-9

Jan 2024

preprint

Effects of Branched-Chain Amino Acids on Skeletal Muscle, Glycemic Control, and Neuropsychological Performance in Elderly Persons with Type 2 Diabetes Mellitus: An Exploratory Randomized Controlled Trial

Nutrients

Jan 2022

journal-article

FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin

iScience

Jan 2021

journal-article

Genome-wide screening of upstream transcription factors using an expression library [version 2; peer review: 2 approved]

Jan 2021

journal-article

Genome-wide screening of upstream transcription factors using an expression library

F1000Research

Jan 2021

journal-article

Genome-wide screening of upstream transcription factors using an expression library

F1000Research

Jan 2021

journal-article

Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1

Biochemical and Biophysical Research Communications

Jan 2019

journal-article

Influence of Intermittent Cold Stimulations on CREB and Its Targeting Genes in Muscle: Investigations into Molecular Mechanisms of Local Cryotherapy

Jan 2019

preprint

Detection of transgenes in gene delivery model mice by adenoviral vector using ddPCR

Genes

Jan 2019

journal-article

Glucocorticoid receptor suppresses gene expression of Rev-erbα (Nr1d1) through interaction with the CLOCK complex

FEBS Letters

Jan 2019

journal-article

Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism

Scientific Reports

Jan 2019

journal-article

A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes

FEBS Letters

Jan 2018

journal-article

Cost-effectiveness of a new opportunistic screening strategy for walk-in fingertip HbA1c testing at community pharmacies in Japan

Diabetes Care

Jan 2018

journal-article

Malondialdehyde-modified LDL-related variables are associated with diabetic kidney disease in type 2 diabetes

Diabetes Research and Clinical Practice

Jan 2018

journal-article

Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance

Endocrinology

Jan 2018

journal-article

A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.

Jan 2017

journal-article

A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes

FEBS Letters

Jan 2017

journal-article

Hepatic Control of Energy Metabolism via the Autonomic Nervous System.

Jan 2017

journal-article

Hepatic control of energy metabolism via the autonomic nervous system

Journal of Atherosclerosis and Thrombosis

Jan 2017

journal-article

The selective PPARα modulator K-877 efficiently activates the PPARα pathway and improves lipid metabolism in mice.

Jan 2017

journal-article

Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice

Journal of Diabetes Investigation

Jan 2017

journal-article

Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry

Biochemical and Biophysical Research Communications

Jan 2017

journal-article

Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry

Biochemical and Biophysical Research Communications

Jan 2017

journal-article

Elovl6 deficiency improves glycemic control in diabetic db/db mice by expanding beta;-cell mass and increasing insulin secretory capacity

Diabetes

Jan 2017

journal-article

New findings on transcriptional regulation of de novo lipogenesis

Seikagaku

Jan 2017

journal-article

Role of hormone-sensitive lipase in leptin-promoted fat loss and glucose lowering

Journal of Atherosclerosis and Thrombosis

Jan 2017

journal-article

KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting

Cell Reports

Jan 2016

journal-article

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.

Jan 2016

journal-article

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα

Scientific Reports

Jan 2016

journal-article

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.

Jan 2016

journal-article

KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.

Jan 2016

journal-article

Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice.

Jan 2016

journal-article

Different effects of eicosapentaenoic and docosahexaenoic acids on atherogenic high- fat diet-induced non-alcoholic fatty liver disease in mice

PLoS ONE

Jan 2016

journal-article

Dyslipidemia and atherosclerosis

Japanese Journal of Clinical Chemistry

Jan 2016

journal-article

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system.

Jan 2016

journal-article

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system

Scientific Reports

Jan 2016

journal-article

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression

Molecular Metabolism

Jan 2016

journal-article

Identification of human ELOVL5 enhancer regions controlled by SREBP.

Jan 2015

journal-article

Identification of human ELOVL5 enhancer regions controlled by SREBP

Biochemical and Biophysical Research Communications

Jan 2015

journal-article

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy.

Jan 2015

journal-article

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy

Biochemical and Biophysical Research Communications

Jan 2015

journal-article

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model.

Jan 2015

journal-article

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr^-/- mouse model

Scientific Reports

Jan 2015

journal-article

Circulating malondialdehyde-modified LDL-related variables and coronary artery stenosis in asymptomatic patients with type 2 diabetes.

Jan 2015

journal-article

Circulating malondialdehyde-modified LDL-related variables and coronary artery stenosis in asymptomatic patients with type 2 diabetes

Journal of Diabetes Research

Jan 2015

journal-article

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.

Jan 2014

journal-article

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes

Endocrinology

Jan 2014

journal-article

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion.

Jan 2014

journal-article

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion

Biochemical and Biophysical Research Communications

Jan 2014

journal-article

Comparison of the Framingham risk score, UK Prospective Diabetes Study (UKPDS) Risk Engine, Japanese Atherosclerosis Longitudinal Study-Existing Cohorts Combine (JALS-ECC) and maximum carotid intima-media thickness for predicting coronary artery stenosis in patients with asymptomatic type 2 diabetes.

Jan 2014

journal-article

Comparison of the Framingham risk score, UK prospective diabetes Study (UKPDS) risk engine, Japanese atherosclerosis longitudinal study-Existing cohorts combine (JALS-ECC) and maximum carotid intima-media thickness for predicting coronary artery stenosis in patients with asymptomatic type 2 diabetes

Journal of Atherosclerosis and Thrombosis

Jan 2014

journal-article

MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo.

Jan 2014

journal-article

MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo

Scientific Reports

Jan 2014

journal-article

Apolipoprotein C-II deficiency with no rare variant in the APOC2 gene.

Jan 2013

journal-article

Apolipoprotein C-II deficiency with no rare variant in the APOC2 gene

Journal of Atherosclerosis and Thrombosis

Jan 2013

journal-article

Erratum: Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization

Nature Communications

Jan 2013

journal-article

Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization

Nature Communications

Jan 2013

journal-article

Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization

Nature Communications

Jan 2013

journal-article

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

Nature Communications

Jan 2013

journal-article

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

Nature Communications

Jan 2013

journal-article

TFE3 Controls Lipid Metabolism in Adipose Tissue of Male Mice by Suppressing Lipolysis and Thermogenesis

Endocrinology

Jan 2013

journal-article

TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis

Endocrinology

Jan 2013

journal-article

TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin

Biochemical and Biophysical Research Communications

Jan 2013

journal-article

Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T3-L1 cells

Biochemical and Biophysical Research Communications

Jan 2012

journal-article

Elovl6 promotes nonalcoholic steatohepatitis

Hepatology

Jan 2012

journal-article

Longitudinal trajectories of HbA 1c and fasting plasma glucose levels during the development of type 2 diabetes: The Toranomon Hospital Health Management Center Study 7 (TOPICS 7)

Diabetes Care

Jan 2012

journal-article

TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice

American Journal of Physiology - Endocrinology and Metabolism

Jan 2012

journal-article

Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c)

Journal of Biological Chemistry

Jan 2011

journal-article

Abrogation of neutral cholesterol ester hydrolytic activity causes adrenal enlargement

Biochemical and Biophysical Research Communications

Jan 2011

journal-article

Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like Factor 5 (KLF5)/Peroxisome Proliferator-activated Receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice

Journal of Biological Chemistry

Jan 2011

journal-article

Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Jan 2011

journal-article

Sterol regulatory element-binding protein-1 determines plasma remnant lipoproteins and accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Jan 2011

journal-article

The powerful combination of in vivo cis-element analysis using IVIS (in vivo Ad-luc) and trans-acting factor screen using the transcription factor expression library (TFEL) to explore the transcriptional cascades regulating nutrient metabolism

Therapeutic Research

Jan 2011

journal-article

Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit

Journal of Biological Chemistry

Jan 2010

journal-article

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin

Journal of Lipid Research

Jan 2010

journal-article

Ablation of Neutral Cholesterol Ester Hydrolase 1 Accelerates Atherosclerosis

Cell Metabolism

Jan 2009

journal-article

Administration of angiotensin II, but not catecholamines, induces accumulation of lipids in the rat heart

European Journal of Pharmacology

Jan 2009

journal-article

Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep^ob/ob mice

Biochemical and Biophysical Research Communications

Jan 2009

journal-article

Nuclear SREBP-1a causes loss of pancreatic β-cells and impaired insulin secretion

Biochemical and Biophysical Research Communications

Jan 2009

journal-article

The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice

Biochemical and Biophysical Research Communications

Jan 2009

journal-article

Cholesterol accumulation and diabetes in pancreatic β-cell-specific SREBP-2 transgenic mice: A new model for lipotoxicity

Journal of Lipid Research

Jan 2008

journal-article

Cyclin-dependent kinase inhibitor, p21^WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance

Journal of Biological Chemistry

Jan 2008

journal-article

Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis

Journal of Lipid Research

Jan 2008

journal-article

Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages

Journal of Biological Chemistry

Jan 2008

journal-article

Mouse Elovl-6 promoter is an SREBP target

Biochemical and Biophysical Research Communications

Jan 2008

journal-article

Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets

Diabetes

Jan 2008

journal-article

A transcription factor of lipid synthesis, sterol regulatory element-binding protein (SREBP)-1a causes G1 cell-cycle arrest after accumulation of cyclin-dependent kinase (cdk) inhibitors

FEBS Journal

Jan 2007

journal-article

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance

Nature Medicine

Jan 2007

journal-article

In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression

Biochemical and Biophysical Research Communications

Jan 2007

journal-article

Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver

Journal of Biological Chemistry

Jan 2007

journal-article

SREBP-1-independent regulation of lipogenic gene expression in adipocytes

Journal of Lipid Research

Jan 2007

journal-article

Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice

Cell Metabolism

Jan 2006

journal-article

Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: A potential role in adipocyte lipolysis

Diabetes

Jan 2006

journal-article

Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver

Journal of Lipid Research

Jan 2006

journal-article

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

Nature Medicine

Jan 2006

journal-article

High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.

Jan 2005

journal-article

High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding

Journal of Biological Chemistry

Jan 2005

journal-article

Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

European Journal of Cancer

Jan 2005

journal-article

High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding

Journal of Biological Chemistry

Jan 2005

journal-article

Lipid synthetic transcription factor SREBP-1a activates p21 ^WAF1/CIP1, a universal cyclin-dependent kinase inhibitor

Molecular and Cellular Biology

Jan 2005

journal-article

Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47

Journal of Biological Chemistry

Jan 2005

journal-article

Transgenic mice overexpressing nuclear SREBP-1c in pancreatic β-cells

Diabetes

Jan 2005

journal-article

Absence of Hormone-sensitive Lipase Inhibits Obesity and Adipogenesis in Lep^ob/ob Mice

Journal of Biological Chemistry

Jan 2004

journal-article

Do Polyunsaturated Fatty Acids Ameliorate Hepatic Steatosis in Obese Mice by SREPB-1 Suppression or by Correcting Essential Fatty Acid Defficiency [5]

Hepatology

Jan 2004

journal-article

Insulin-Independent Induction of Sterol Regulatory Element-Binding Protein-1c Expression in the Livers of Streptozotocin-Treated Mice

Diabetes

Jan 2004

journal-article

Microarray Analyses of SREBP-1 Target Genes

Unraveling Lipid Metabolism With Microarrays

Jan 2004

other

Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREPB-1 suppression or by correcting essential fatty acid deficiency - Reply

Hepatology

Jan 2004

journal-article

SREBP-1 Interacts with Hepatocyte Nuclear Factor-4α and Interferes with PGC-1 Recruitment to Suppress Hepatic Gluconeogenic Genes

Journal of Biological Chemistry

Jan 2004

journal-article

SREBPs suppress IRS-2-mediated insulin signalling in the liver

Nature Cell Biology

Jan 2004

journal-article

Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide

Journal of Biological Chemistry

Jan 2004

journal-article

p53 Involvement in the pathogenesis of fatty liver disease

Journal of Biological Chemistry

Jan 2004

journal-article

Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression.

Jan 2003

journal-article

Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARS suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling

Molecular Endocrinology

Jan 2003

journal-article

Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling

Molecular Endocrinology

Jan 2003

journal-article

Early Embryonic Lethality Caused by Targeted Disruption of the 3-Hydroxy-3-methylglutaryl-CoA Reductase Gene

Journal of Biological Chemistry

Jan 2003

journal-article

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products

Journal of Biological Chemistry

Jan 2003

journal-article

Hepatic Akt Activation Induces Marked Hypoglycemia, Hepatomegaly, and Hypertriglyceridemia with Sterol Regulatory Element Binding Protein Involvement

Diabetes

Jan 2003

journal-article

p53 activation in adipocytes of obese mice

Journal of Biological Chemistry

Jan 2003

journal-article

Lipolysis in the absence of hormone-sensitive lipase: evidence for a common mechanism regulating distinct lipases.

Jan 2002

journal-article

Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes.

Jan 2002

journal-article

Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.

Jan 2002

journal-article

Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha.

Jan 2002

journal-article

A kindred of familial acromegaly without evidence for linkage to MEN-1 locus

Endocrine Journal

Jan 2002

journal-article

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep^ob/Lep^ob mice

Journal of Biological Chemistry

Jan 2002

journal-article

Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status

American Journal of Physiology-Endocrinology and Metabolism

Jan 2002

journal-article

Do sex steroids regulate glutamine synthesis with age?

American Journal of Physiology - Endocrinology and Metabolism

Jan 2002

journal-article

Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase

Journal of Biological Chemistry

Jan 2002

journal-article

Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

Journal of Biological Chemistry

Jan 2002

journal-article

Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL.

Jan 2001

journal-article

[Gene therapy for hyperlipoproteinemia].

Jan 2001

journal-article

Asialoglycoprotein receptor deficiency in mice lacking the major receptor subunit. Its obligate requirement for the stable expression of oligomeric receptor

Journal of Biological Chemistry

Jan 2001

journal-article

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

Molecular and Cellular Biology

Jan 2001

journal-article

Severe Hypercholesterolemia, Hypertriglyceridemia, and Atherosclerosis in Mice Lacking Both Leptin and the Low Density Lipoprotein Receptor

Journal of Biological Chemistry

Jan 2001

journal-article

The LDL receptor is the major pathway for β-VLDL uptake by mouse peritoneal macrophages

Atherosclerosis

Jan 2001

journal-article

Thiazolidinedione- and tumor necrosis factor alpha-induced downregulation of peroxisome proliferator-activated receptor gamma mRNA in differentiated 3T3-L1 adipocytes

Metabolism: Clinical and Experimental

Jan 2001

journal-article

Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene.

Jan 2000

journal-article

Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.

Jan 2000

journal-article

Novel mutations in the microsomal triglyceride transfer protein gene causing abetalipoproteinemia.

Jan 2000

journal-article

Absence of ACAT-1 attenuates atherosclerosis but 'causes dry eye and cutaneous xanthomatosis mice with congenital hyperlipidemia

Journal of Biological Chemistry

Jan 2000

journal-article

Diversity of voltage-gated sodium channels in the ascidian larval nervous system

Biochemical and Biophysical Research Communications

Jan 2000

journal-article

Diversity of voltage-gated sodium channels in the ascidian larval nervous system

Biochemical and Biophysical Research Communications

Jan 2000

journal-article

Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity

Proceedings of the National Academy of Sciences of the United States of America

Jan 2000

journal-article

Overexpressed lipoprotein lipase protects against atherosclerosis in apolipoprotein E knockout mice.

Jan 1999

journal-article

A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids

Journal of Biological Chemistry

Jan 1999

journal-article

Overexpressed lipoprotein lipase protects against atherosclerosis in apolipoprotein E knockout mice

Journal of Lipid Research

Jan 1999

journal-article

Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

Journal of Biological Chemistry

Jan 1999

journal-article

Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1.

Jan 1998

journal-article

[A case of fatal pneumonia caused by Legionella pneumophila serogroup 6 developed after drowning in a public bath].

Jan 1997

journal-article

Apoptotic cell death in atherosclerotic plaques of hyperlipidemic knockout mice

Atherosclerosis

Jan 1997

journal-article

Naoya Yahagi

Work

Jichi Medical University

University of Tsukuba

University of Tsukuba

Education

University of Tokyo

University of Tokyo

Publications

Detection Method for Gene Doping in a Mouse Model Expressing Human Erythropoietin from Adeno-Associated Virus Vector-9

Community-based HbA1c testing programme for early detection of undiagnosed diabetes in community pharmacy

Evaluation of the Effectiveness of Feedback in a Remote Monitoring Home-Based Training System for Workers: A Medium-Scale Randomized Parallel-Group Controlled Trial

Evaluation of the Effectiveness of Feedback in a Remote Monitoring Home-Based Training System for Workers: A Medium-Scale Randomized Parallel-Group Controlled Trial

Detection Method for Gene Doping in a Mouse Model Expressing Human Erythropoietin from Adeno-Associated Virus Vector-9

Detection Method for Gene Doping in a Mouse Model Expressing Human Erythropoietin from Adeno-Associated Virus Vector-9

Detection Method for Gene Doping in a Mouse Model Expressing Human Erythropoietin from Adeno-Associated Virus Vector-9

Effects of Branched-Chain Amino Acids on Skeletal Muscle, Glycemic Control, and Neuropsychological Performance in Elderly Persons with Type 2 Diabetes Mellitus: An Exploratory Randomized Controlled Trial

FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin

Genome-wide screening of upstream transcription factors using an expression library [version 2; peer review: 2 approved]

Genome-wide screening of upstream transcription factors using an expression library

Genome-wide screening of upstream transcription factors using an expression library

Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1

Influence of Intermittent Cold Stimulations on CREB and Its Targeting Genes in Muscle: Investigations into Molecular Mechanisms of Local Cryotherapy

Detection of transgenes in gene delivery model mice by adenoviral vector using ddPCR

Glucocorticoid receptor suppresses gene expression of Rev-erbα (Nr1d1) through interaction with the CLOCK complex

Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism

A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes

Cost-effectiveness of a new opportunistic screening strategy for walk-in fingertip HbA1c testing at community pharmacies in Japan

Malondialdehyde-modified LDL-related variables are associated with diabetic kidney disease in type 2 diabetes

Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance

A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.

A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes

Hepatic Control of Energy Metabolism via the Autonomic Nervous System.

Hepatic control of energy metabolism via the autonomic nervous system

The selective PPARα modulator K-877 efficiently activates the PPARα pathway and improves lipid metabolism in mice.

Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice

Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry

Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry

Elovl6 deficiency improves glycemic control in diabetic db/db mice by expanding beta;-cell mass and increasing insulin secretory capacity

New findings on transcriptional regulation of de novo lipogenesis

Role of hormone-sensitive lipase in leptin-promoted fat loss and glucose lowering

KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.

KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.

Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice.

Different effects of eicosapentaenoic and docosahexaenoic acids on atherogenic high- fat diet-induced non-alcoholic fatty liver disease in mice

Dyslipidemia and atherosclerosis

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system.

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression

Identification of human ELOVL5 enhancer regions controlled by SREBP.

Identification of human ELOVL5 enhancer regions controlled by SREBP

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy.

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model.

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr-/- mouse model

Circulating malondialdehyde-modified LDL-related variables and coronary artery stenosis in asymptomatic patients with type 2 diabetes.

Circulating malondialdehyde-modified LDL-related variables and coronary artery stenosis in asymptomatic patients with type 2 diabetes

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion.

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion

MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo.

MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo

Apolipoprotein C-II deficiency with no rare variant in the APOC2 gene.

Apolipoprotein C-II deficiency with no rare variant in the APOC2 gene

Erratum: Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization

Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization

Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

TFE3 Controls Lipid Metabolism in Adipose Tissue of Male Mice by Suppressing Lipolysis and Thermogenesis

TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis

TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin

Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T3-L1 cells

Elovl6 promotes nonalcoholic steatohepatitis

Longitudinal trajectories of HbA 1c and fasting plasma glucose levels during the development of type 2 diabetes: The Toranomon Hospital Health Management Center Study 7 (TOPICS 7)

TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr^-/- mouse model

Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep^ob/ob mice

Cyclin-dependent kinase inhibitor, p21^WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance

Lipid synthetic transcription factor SREBP-1a activates p21 ^WAF1/CIP1, a universal cyclin-dependent kinase inhibitor

Absence of Hormone-sensitive Lipase Inhibits Obesity and Adipogenesis in Lep^ob/ob Mice

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep^ob/Lep^ob mice